Cross-Platform Array Screening Identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as Genes Frequently Silenced by Methylation in Melanoma

por Bonazzi, Vanessa F., Nancarrow, Derek J., Stark, Mitchell S., Moser, Ralf J., Boyle, Glen M., Aoude, Lauren G., Schmidt, Christopher, Hayward, Nicholas K.
Publicado 2011

A BAP1 Mutation in a Danish Family Predisposes to Uveal Melanoma and Other Cancers

por Aoude, Lauren G., Wadt, Karin, Bojesen, Anders, Crüger, Dorthe, Borg, Åke, Trent, Jeffrey M., Brown, Kevin M., Gerdes, Anne-Marie, Jönsson, Göran, Hayward, Nicholas K.
Publicado 2013

The oesophageal adenocarcinoma tumour immune microenvironment dictates outcomes with different modalities of neoadjuvant therapy – results from the AGITG DOCTOR trial and the cance...

por Lonie, James M., Brosda, Sandra, Bonazzi, Vanessa F., Aoude, Lauren G., Patel, Kalpana, Brown, Ian, Sharma, Sowmya, Lampe, Guy, Addala, Venkateswar, Koufariotis, Lambros T., Wood, Scott, Waddell, Nicola, Dolcetti, Riccardo, Barbour, Andrew P.
Publicado 2023

Assessment of PALB2 as a Candidate Melanoma Susceptibility Gene

por Aoude, Lauren G., Xu, Mai, Zhao, Zhen Zhen, Kovacs, Michael, Palmer, Jane M., Johansson, Peter, Symmons, Judith, Trent, Jeffrey M., Martin, Nicholas G., Montgomery, Grant W., Brown, Kevin M., Hayward, Nicholas K.
Publicado 2014

Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients

por Aoude, Lauren G., Bonazzi, Vanessa F., Brosda, Sandra, Patel, Kalpana, Koufariotis, Lambros T., Oey, Harald, Nones, Katia, Wood, Scott, Pearson, John V., Lonie, James M., Arneil, Melissa, Atkinson, Victoria, Smithers, B. Mark, Waddell, Nicola, Barbour, Andrew P.
Publicado 2020

Germline TERT promoter mutations are rare in familial melanoma

por Harland, Mark, Petljak, Mia, Robles-Espinoza, Carla Daniela, Ding, Zhihao, Gruis, Nelleke A., van Doorn, Remco, Pooley, Karen A., Dunning, Alison M., Aoude, Lauren G., Wadt, Karin A. W., Gerdes, Anne-Marie, Brown, Kevin M., Hayward, Nicholas K., Newton-Bishop, Julia A., Adams, David J., Bishop, D. Timothy
Publicado 2015

Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4

por Johansson, Peter, Aoude, Lauren G., Wadt, Karin, Glasson, William J., Warrier, Sunil K., Hewitt, Alex W., Kiilgaard, Jens Folke, Heegaard, Steffen, Isaacs, Tim, Franchina, Maria, Ingvar, Christian, Vermeulen, Tersia, Whitehead, Kevin J., Schmidt, Christopher W., Palmer, Jane M., Symmons, Judith, Gerdes, Anne-Marie, Jönsson, Göran, Hayward, Nicholas K.
Publicado 2015

Molecular Characterization of Melanoma Cases in Denmark Suspected of Genetic Predisposition

por Wadt, Karin A. W., Aoude, Lauren G., Krogh, Lotte, Sunde, Lone, Bojesen, Anders, Grønskov, Karen, Wartacz, Nine, Ek, Jakob, Tolstrup-Andersen, Morten, Klarskov-Andersen, Mette, Borg, Åke, Heegaard, Steffen, Kiilgaard, Jens F., Hansen, Thomas V. O., Klein, Kerenaftali, Jönsson, Göran, Drzewiecki, Krzysztof T., Dunø, Morten, Hayward, Nicholas K., Gerdes, Anne-Marie
Publicado 2015

Complex structural rearrangements are present in high-grade dysplastic Barrett’s oesophagus samples

por Newell, Felicity, Patel, Kalpana, Gartside, Michael, Krause, Lutz, Brosda, Sandra, Aoude, Lauren G., Loffler, Kelly A., Bonazzi, Vanessa F., Patch, Ann-Marie, Kazakoff, Stephen H., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Lampe, Guy, Lord, Reginald V., Whiteman, David C., Pearson, John V., Nones, Katia, Waddell, Nicola, Barbour, Andrew P.
Publicado 2019

Multiplex melanoma families are enriched for polygenic risk

por Law, Matthew H, Aoude, Lauren G, Duffy, David L, Long, Georgina V, Johansson, Peter A, Pritchard, Antonia L, Khosrotehrani, Kiarash, Mann, Graham J, Montgomery, Grant W, Iles, Mark M, Cust, Anne E, Palmer, Jane M, Shannon, Kerwin F, Spillane, Andrew J, Stretch, Jonathan R, Thompson, John F, Saw, Robyn P M, Scolyer, Richard A, Martin, Nicholas G, Hayward, Nicholas K, MacGregor, Stuart
Publicado 2020

Frequent somatic MAP3K5 and MAP3K9 mutations in metastatic melanoma identified by exome sequencing

por Stark, Mitchell S, Woods, Susan L, Gartside, Michael G, Bonazzi, Vanessa F, Dutton-Regester, Ken, Aoude, Lauren G, Chow, Donald, Sereduk, Chris, Niemi, Natalie M, Tang, Nanyun, Ellis, Jonathan J, Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M, Pollak, Thomas, Youngkin, David, Brooks, Bradford R, Lanagan, Catherine, Schmidt, Christopher W, Kobe, Bostjan, MacKeigan, Jeffrey P, Yin, Hongwei, Brown, Kevin M, Gibbs, Richard, Trent, Jeffrey, Hayward, Nicholas K
Publicado 2011

POT1 loss-of-function variants predispose to familial melanoma

por Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J., Aoude, Lauren G., Quesada, Víctor, Ding, Zhihao, Pooley, Karen A., Pritchard, Antonia L., Tiffen, Jessamy C., Petljak, Mia, Palmer, Jane M., Symmons, Judith, Johansson, Peter, Stark, Mitchell S., Gartside, Michael G., Snowden, Helen, Montgomery, Grant W., Martin, Nicholas G., Liu, Jimmy Z., Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M., Dunning, Alison M., Keane, Thomas M., López-Otín, Carlos, Gruis, Nelleke A., Hayward, Nicholas K., Bishop, D. Timothy, Newton-Bishop, Julia A., Adams, David J.
Publicado 2014

Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy

por M. Naeini, Marjan, Newell, Felicity, Aoude, Lauren G., Bonazzi, Vanessa F., Patel, Kalpana, Lampe, Guy, Koufariotis, Lambros T., Lakis, Vanessa, Addala, Venkateswar, Kondrashova, Olga, Johnston, Rebecca L., Sharma, Sowmya, Brosda, Sandra, Holmes, Oliver, Leonard, Conrad, Wood, Scott, Xu, Qinying, Thomas, Janine, Walpole, Euan, Tao Mai, G., Ackland, Stephen P., Martin, Jarad, Burge, Matthew, Finch, Robert, Karapetis, Christos S., Shannon, Jenny, Nott, Louise, Bohmer, Robert, Wilson, Kate, Barnes, Elizabeth, Zalcberg, John R., Mark Smithers, B., Simes, John, Price, Timothy, Gebski, Val, Nones, Katia, Watson, David I., Pearson, John V., Barbour, Andrew P., Waddell, Nicola
Publicado 2023

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

por Yokoyama, Satoru, Woods, Susan L., Boyle, Glen M., Aoude, Lauren G., MacGregor, Stuart, Zismann, Victoria, Gartside, Michael, Cust, Anne E., Haq, Rizwan, Harland, Mark, Taylor, John C., Duffy, David L., Holohan, Kelly, Dutton-Regester, Ken, Palmer, Jane M., Bonazzi, Vanessa, Stark, Mitchell S., Symmons, Judith, Law, Matthew H., Schmidt, Christopher, Lanagan, Cathy, O’Connor, Linda, Holland, Elizabeth A., Schmid, Helen, Maskiell, Judith A., Jetann, Jodie, Ferguson, Megan, Jenkins, Mark A., Kefford, Richard F., Giles, Graham G., Armstrong, Bruce K., Aitken, Joanne F., Hopper, John L., Whiteman, David C., Pharoah, Paul D., Easton, Douglas F., Dunning, Alison M., Newton-Bishop, Julia A., Montgomery, Grant W., Martin, Nicholas G., Mann, Graham J., Bishop, D. Timothy, Tsao, Hensin, Trent, Jeffrey M., Fisher, David E., Hayward, Nicholas K., Brown, Kevin M.
Publicado 2011