Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α

por Langemann, Doerte, Trochimiuk, Magdalena, Appl, Birgit, Hundsdoerfer, Patrick, Reinshagen, Konrad, Eschenburg, Georg
Publicado 2017

Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L

por Najem, Safiullah, Langemann, Doerte, Appl, Birgit, Trochimiuk, Magdalena, Hundsdoerfer, Patrick, Reinshagen, Konrad, Eschenburg, Georg
Publicado 2016

Development of an improved murine model of necrotizing enterocolitis shows the importance of neutrophils in NEC pathogenesis

por Klinke, Michaela, Vincent, Deirdre, Trochimiuk, Magdalena, Appl, Birgit, Tiemann, Bastian, Reinshagen, Konrad, Pagerols Raluy, Laia, Boettcher, Michael
Publicado 2020

NEC is likely a NETs dependent process and markers of NETosis are predictive of NEC in mice and humans

por Vincent, Deirdre, Klinke, Michaela, Eschenburg, Georg, Trochimiuk, Magdalena, Appl, Birgit, Tiemann, Bastian, Bergholz, Robert, Reinshagen, Konrad, Boettcher, Michael
Publicado 2018

Time- and dose-dependent inhibition of neutrophil extracellular trap formation by blocking of the interleukin-1 receptor

por Wadehn, Hannah, Raluy, Laia Pagerols, Kolman, Jan, Duecker, Charlotte, Trochimiuk, Magdalena, Appl, Birgit, Boettcher, Michael, Reinshagen, Konrad, Trah, Julian
Publicado 2021

The Inhibitory Effect of Curosurf(®) and Alveofact(®) on the Formation of Neutrophil Extracellular Traps

por Schulz, Annabell, Pagerols Raluy, Laia, Kolman, Jan Philipp, Königs, Ingo, Trochimiuk, Magdalena, Appl, Birgit, Reinshagen, Konrad, Boettcher, Michael, Trah, Julian
Publicado 2021

Biliatresone induces cholangiopathy in C57BL/6J neonates

por Schmidt, Hans Christian, Hagens, Johanna, Schuppert, Pauline, Appl, Birgit, Raluy, Laia Pagerols, Trochimiuk, Magdalena, Philippi, Clara, Li, Zhongwen, Reinshagen, Konrad, Tomuschat, Christian
Publicado 2023

Markers of neutrophil activation and extracellular traps formation are predictive of appendicitis in mice and humans: a pilot study

por Boettcher, Michael, Esser, Melina, Trah, Julian, Klohs, Stefan, Mokhaberi, Nariman, Wenskus, Julia, Trochimiuk, Madgalena, Appl, Birgit, Reinshagen, Konrad, Raluy, Laia Pagerols, Klinke, Michaela
Publicado 2020

Therapeutic Targeting of Neutrophil Extracellular Traps Improves Primary and Secondary Intention Wound Healing in Mice

por Heuer, Annika, Stiel, Carolin, Elrod, Julia, Königs, Ingo, Vincent, Deirdre, Schlegel, Patrick, Trochimiuk, Magdalena, Appl, Birgit, Reinshagen, Konrad, Raluy, Laia Pagerols, Boettcher, Michael
Publicado 2021

Lithocholic bile acid induces apoptosis in human nephroblastoma cells: a non-selective treatment option

por Trah, Julian, Arand, Jonas, Oh, Jun, Pagerols-Raluy, Laia, Trochimiuk, Magdalena, Appl, Birgit, Heidelbach, Hannah, Vincent, Deirdre, Saleem, Moin A., Reinshagen, Konrad, Mühlig, Anne K., Boettcher, Michael
Publicado 2020

NET Release of Long-Term Surviving Neutrophils

por Kolman, Jan Philipp, Pagerols Raluy, Laia, Müller, Ingo, Nikolaev, Viacheslav O., Trochimiuk, Magdalena, Appl, Birgit, Wadehn, Hannah, Dücker, Charlotte Maria, Stoll, Fabian David, Boettcher, Michael, Reinshagen, Konrad, Trah, Julian
Publicado 2022

Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions

por Elrod, Julia, Heuer, Annika, Knopf, Jasmin, Schoen, Janina, Schönfeld, Lavinia, Trochimiuk, Magdalena, Stiel, Carolin, Appl, Birgit, Raluy, Laia Pagerols, Saygi, Ceren, Zlatar, Leticija, Hosari, Sami, Royzman, Dmytro, Winkler, Thomas H., Lochnit, Günter, Leppkes, Moritz, Grützmann, Robert, Schett, Georg, Tomuschat, Christian, Reinshagen, Konrad, Herrmann, Martin, Fuchs, Tobias A., Boettcher, Michael
Publicado 2023