Investigations in West Syndrome: Which, When and Why

por Appleton, Richard E.
Publicado 2015

The role of lumbar puncture in children with suspected central nervous system infection

por Kneen, Rachel, Solomon, Tom, Appleton, Richard
Publicado 2002

Optimal Management of Status Epilepticus in Children in the Emergency Setting: A Review of Recent Advances

por Messahel, Shrouk, Bracken, Louise, Appleton, Richard
Publicado 2022

Doing challenging research studies in a patient-centred way: a qualitative study to inform a randomised controlled trial in the paediatric emergency care setting

por Woolfall, Kerry, Young, Bridget, Frith, Lucy, Appleton, Richard, Iyer, Anand, Messahel, Shrouk, Hickey, Helen, Gamble, Carrol
Publicado 2014

Resource implications of preparing individual participant data from a clinical trial to share with external researchers

por Tudur Smith, Catrin, Nevitt, Sarah, Appelbe, Duncan, Appleton, Richard, Dixon, Pete, Harrison, Janet, Marson, Anthony, Williamson, Paula, Tremain, Elizabeth
Publicado 2017

Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome

por Devinsky, Orrin, Patel, Anup D., Thiele, Elizabeth A., Wong, Matthew H., Appleton, Richard, Harden, Cynthia L., Greenwood, Sam, Morrison, Gilmour, Sommerville, Kenneth
Publicado 2018

Children’s views on research without prior consent in emergency situations: a UK qualitative study

por Roper, Louise, Sherratt, Frances C, Young, Bridget, McNamara, Paul, Dawson, Angus, Appleton, Richard, Crawley, Esther, Frith, Lucy, Gamble, Carrol, Woolfall, Kerry
Publicado 2018

Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: a mixed-method evaluation of site training – a Paediatric Emergency Research in the United King...

por Woolfall, Kerry, Roper, Louise, Humphreys, Amy, Lyttle, Mark D., Messahel, Shrouk, Lee, Elizabeth, Noblet, Joanne, Iyer, Anand, Gamble, Carrol, Hickey, Helen, Rainford, Naomi, Appleton, Richard
Publicado 2019

Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials

por Roper, Louise, Lyttle, Mark D, Gamble, Carrol, Humphreys, Amy, Messahel, Shrouk, Lee, Elizabeth D, Noblet, Joanne, Hickey, Helen, Rainford, Naomi, Iyer, Anand, Appleton, Richard, Woolfall, Kerry
Publicado 2021

Planning for success: overcoming challenges to recruitment and conduct of an open-label emergency department–led paediatric trial

por Roper, Louise, Lyttle, Mark D, Gamble, Carrol, Humphreys, Amy, Messahel, Shrouk, Lee, Elizabeth D, Noblet, Joanne, Hickey, Helen, Rainford, Naomi, Iyer, Anand, Appleton, Richard, Woolfall, Kerry
Publicado 2021

Clinical Drug Development in Epilepsy Revisited: A Proposal for a New Paradigm Streamlined Using Extrapolation

por Wadsworth, Ian, Jaki, Thomas, Sills, Graeme J., Appleton, Richard, Cross, J. Helen, Marson, Anthony G., Martland, Tim, McLellan, Ailsa, Smith, Philip E. M., Pellock, John M., Hampson, Lisa V.
Publicado 2016

Genetic regulation of gene expression in the epileptic human hippocampus

por Mirza, Nasir, Appleton, Richard, Burn, Sasha, du Plessis, Daniel, Duncan, Roderick, Farah, Jibril Osman, Feenstra, Bjarke, Hviid, Anders, Josan, Vivek, Mohanraj, Rajiv, Shukralla, Arif, Sills, Graeme J., Marson, Anthony G., Pirmohamed, Munir
Publicado 2017

Emergency treatment with levetiracetam or phenytoin in status epilepticus in children—the EcLiPSE study: study protocol for a randomised controlled trial

por Lyttle, Mark D., Gamble, Carrol, Messahel, Shrouk, Hickey, Helen, Iyer, Anand, Woolfall, Kerry, Humphreys, Amy, Bacon, Naomi E. A., Roper, Louise, Babl, Franz E., Dalziel, Stuart R., Ryan, Mary, Appleton, Richard E.
Publicado 2017

Rituximab monitoring and redosing in pediatric neuromyelitis optica spectrum disorder

por Nosadini, Margherita, Alper, Gulay, Riney, Catherine J., Benson, Leslie A., Mohammad, Shekeeb S., Ramanathan, Sudarshini, Nolan, Melinda, Appleton, Richard, Leventer, Richard J., Deiva, Kumaran, Brilot, Fabienne, Gorman, Mark P., Waldman, Amy T., Banwell, Brenda, Dale, Russell C.
Publicado 2016

Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial

por Lyttle, Mark D, Rainford, Naomi E A, Gamble, Carrol, Messahel, Shrouk, Humphreys, Amy, Hickey, Helen, Woolfall, Kerry, Roper, Louise, Noblet, Joanne, Lee, Elizabeth D, Potter, Sarah, Tate, Paul, Iyer, Anand, Evans, Vicki, Appleton, Richard E
Publicado 2019

Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epileps...

por Balabanova, Silviya, Taylor, Claire, Sills, Graeme, Burnside, Girvan, Plumpton, Catrin, Smith, Phil E M, Appleton, Richard, Leach, John Paul, Johnson, Michael, Baker, Gus, Pirmohamed, Munir, Hughes, Dyfrig A, Williamson, Paula R, Tudur-Smith, Catrin, Marson, Anthony Guy
Publicado 2020

The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, mult...

por Marson, Anthony, Burnside, Girvan, Appleton, Richard, Smith, Dave, Leach, John Paul, Sills, Graeme, Tudur-Smith, Catrin, Plumpton, Catrin, Hughes, Dyfrig A, Williamson, Paula, Baker, Gus A, Balabanova, Silviya, Taylor, Claire, Brown, Richard, Hindley, Dan, Howell, Stephen, Maguire, Melissa, Mohanraj, Rajiv, Smith, Philip E
Publicado 2021

The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inf...

por Marson, Anthony, Burnside, Girvan, Appleton, Richard, Smith, Dave, Leach, John Paul, Sills, Graeme, Tudur-Smith, Catrin, Plumpton, Catrin, Hughes, Dyfrig A, Williamson, Paula, Baker, Gus A, Balabanova, Silviya, Taylor, Claire, Brown, Richard, Hindley, Dan, Howell, Stephen, Maguire, Melissa, Mohanraj, Rajiv, Smith, Philip E
Publicado 2021

Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology

por Catarino, Claudia B., Liu, Joan Y.W., Liagkouras, Ioannis, Gibbons, Vaneesha S., Labrum, Robyn W., Ellis, Rachael, Woodward, Cathy, Davis, Mary B., Smith, Shelagh J., Cross, J. Helen, Appleton, Richard E., Yendle, Simone C., McMahon, Jacinta M., Bellows, Susannah T., Jacques, Thomas S., Zuberi, Sameer M., Koepp, Matthias J., Martinian, Lillian, Scheffer, Ingrid E., Thom, Maria, Sisodiya, Sanjay M.
Publicado 2011

Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care

por Annear, Nicholas M. P., Appleton, Richard E., Bassi, Zahabiyah, Bhatt, Rupesh, Bolton, Patrick F., Crawford, Pamela, Crowe, Alex, Tossi, Maureen, Elmslie, Frances, Finlay, Eric, Gale, Daniel P., Henderson, Alex, Jones, Elizabeth A., Johnson, Simon R., Joss, Shelagh, Kerecuk, Larissa, Lipkin, Graham, Morrison, Patrick J., O'Callaghan, Finbar J., Cadwgan, Jill, Ong, Albert C. M., Sampson, Julian R., Shepherd, Charles, Kingswood, J. Chris
Publicado 2019