Natural Inhibitors of Amyloid Aggregation

por Tortora, Paolo, Aprile, Francesco A.
Publicado 2023

Methods of probing the interactions between small molecules and disordered proteins

por Heller, Gabriella T., Aprile, Francesco A., Vendruscolo, Michele
Publicado 2017

Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures

por Ikenoue, Tatsuya, Aprile, Francesco A., Sormanni, Pietro, Vendruscolo, Michele
Publicado 2021

A Facile Method to Produce N-Terminally Truncated α-Synuclein

por Thrush, Rebecca J., Vadukul, Devkee M., Aprile, Francesco A.
Publicado 2022

A Chemical Mutagenesis Approach to Insert Post-translational Modifications in Aggregation-Prone Proteins

por Ge, Ying, Masoura, Athina, Yang, Jingzhou, Aprile, Francesco A.
Publicado 2022

Structure of a low-population intermediate state in the release of an enzyme product

por De Simone, Alfonso, Aprile, Francesco A, Dhulesia, Anne, Dobson, Christopher M, Vendruscolo, Michele
Publicado 2015

The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation

por Aprile, Francesco A., Källstig, Emma, Limorenko, Galina, Vendruscolo, Michele, Ron, David, Hansen, Christian
Publicado 2017

Author Correction: The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation

por Aprile, Francesco A., Källstig, Emma, Limorenko, Galina, Vendruscolo, Michele, Ron, David, Hansen, Christian
Publicado 2018

Site-Specific (68)Ga Radiolabeling of Trastuzumab Fab via Methionine for ImmunoPET Imaging

por Yue, Thomas T. C., Ge, Ying, Aprile, Francesco A., Ma, Michelle T., Pham, Truc T., Long, Nicholas J.
Publicado 2023

Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles

por Perni, Michele, Aprile, Francesco A., Casford, Sam, Mannini, Benedetta, Sormanni, Pietro, Dobson, Christopher M., Vendruscolo, Michele
Publicado 2017

α-Synuclein Aggregation Is Triggered by Oligomeric Amyloid-β 42 via Heterogeneous Primary Nucleation

por Vadukul, Devkee M., Papp, Marcell, Thrush, Rebecca J., Wang, Jielei, Jin, Yiyun, Arosio, Paolo, Aprile, Francesco A.
Publicado 2023

Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates

por Wright, Maya A., Aprile, Francesco A., Arosio, Paolo, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Publicado 2015

Systematic Activity Maturation of a Single-Domain Antibody with Non-canonical Amino Acids through Chemical Mutagenesis

por Lindstedt, Philip R., Aprile, Francesco A., Sormanni, Pietro, Rakoto, Robertinah, Dobson, Christopher M., Bernardes, Gonçalo J.L., Vendruscolo, Michele
Publicado 2021

Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method

por Aprile, Francesco A., Sormanni, Pietro, Perni, Michele, Arosio, Paolo, Linse, Sara, Knowles, Tuomas P. J., Dobson, Christopher M., Vendruscolo, Michele
Publicado 2017

The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli

por Invernizzi, Gaetano, Aprile, Francesco A., Natalello, Antonino, Ghisleni, Andrea, Penco, Amanda, Relini, Annalisa, Doglia, Silvia M., Tortora, Paolo, Regonesi, Maria E.
Publicado 2012

Structure and Dynamics of the Integrin LFA-1 I-Domain in the Inactive State Underlie its Inside-Out/Outside-In Signaling and Allosteric Mechanisms

por Kukic, Predrag, Alvin Leung, Hoi Tik, Bemporad, Francesco, Aprile, Francesco A., Kumita, Janet R., De Simone, Alfonso, Camilloni, Carlo, Vendruscolo, Michele
Publicado 2015

Modulation of amyloid-β aggregation by metal complexes with a dual binding mode and their delivery across the blood–brain barrier using focused ultrasound

por Chan, Tiffany G., Ruehl, Carmen L., Morse, Sophie V., Simon, Michelle, Rakers, Viktoria, Watts, Helena, Aprile, Francesco A., Choi, James J., Vilar, Ramon
Publicado 2021

Hsp70 Oligomerization Is Mediated by an Interaction between the Interdomain Linker and the Substrate-Binding Domain

por Aprile, Francesco A., Dhulesia, Anne, Stengel, Florian, Roodveldt, Cintia, Benesch, Justin L. P., Tortora, Paolo, Robinson, Carol V., Salvatella, Xavier, Dobson, Christopher M., Cremades, Nunilo
Publicado 2013

Unveiling the Rational Development of Stimuli-Responsive Silk Fibroin-Based Ionogel Formulations

por Shmool, Talia A., Martin, Laura K., Jirkas, Andreas, Matthews, Richard P., Constantinou, Anna P., Vadukul, Devkee M., Georgiou, Theoni K., Aprile, Francesco A., Hallett, Jason P.
Publicado 2023

Cooperative Assembly of Hsp70 Subdomain Clusters

por Wright, Maya A., Aprile, Francesco A., Bellaiche, Mathias M. J., Michaels, Thomas C. T., Müller, Thomas, Arosio, Paolo, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Publicado 2018