Leveraging Population Genomics to Enhance Preventive Cardio-Oncology

por Gaziano, Liam, Aragam, Krishna G.
Publicado 2022

“Road Map” to Improving Enrollment in Cardiac Rehabilitation: Identifying Barriers and Evaluating Alternatives

por Pirruccello, James P., Traynor, Kathleen, Aragam, Krishna G.
Publicado 2017

Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease

por Trinder, Mark, Uddin, Md Mesbah, Finneran, Phoebe, Aragam, Krishna G., Natarajan, Pradeep
Publicado 2020

Prognosis of patients with secondary mitral regurgitation and reduced ejection fraction

por Mowakeaa, Samer, Dwivedi, Aeshita, Grossman, Jason R, Parikh, Gaurav, Curillova, Zelmira, Aragam, Krishna G, Elmariah, Sammy, Kinlay, Scott, Aragam, Jayashri
Publicado 2018

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank

por Hindy, George, Åkesson, Kristina E., Melander, Olle, Aragam, Krishna G., Haas, Mary E., Nilsson, Peter M., Kadam, Umesh T., Orho‐Melander, Marju
Publicado 2019

Genetic Association of Body Mass Index With Pathologic Left Ventricular Remodeling

por Biddinger, Kiran J., Pirruccello, James P., Khurshid, Shaan, Natarajan, Pradeep, Ho, Jennifer E., Lubitz, Steven A., Ellinor, Patrick T., Aragam, Krishna G.
Publicado 2022

Does Simplicity Compromise Accuracy in ACS Risk Prediction? A Retrospective Analysis of the TIMI and GRACE Risk Scores

por Aragam, Krishna G., Tamhane, Umesh U., Kline-Rogers, Eva, Li, Jin, Fox, Keith A. A., Goodman, Shaun G., Eagle, Kim A., Gurm, Hitinder S.
Publicado 2009

Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease

por Biddinger, Kiran J., Emdin, Connor A., Haas, Mary E., Wang, Minxian, Hindy, George, Ellinor, Patrick T., Kathiresan, Sekar, Khera, Amit V., Aragam, Krishna G.
Publicado 2022

An expanded repertoire of intensity-dependent exercise-responsive plasma proteins tied to loci of human disease risk

por Guseh, J. Sawalla, Churchill, Timothy W., Yeri, Ashish, Lo, Claire, Brown, Marcel, Houstis, Nicholas E., Aragam, Krishna G., Lieberman, Daniel E., Rosenzweig, Anthony, Baggish, Aaron L.
Publicado 2020

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

por Khera, Amit V., Chaffin, Mark, Aragam, Krishna G., Haas, Mary E., Roselli, Carolina, Choi, Seung Hoan, Natarajan, Pradeep, Lander, Eric S., Lubitz, Steven A., Ellinor, Patrick T., Kathiresan, Sekar
Publicado 2018

Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease

por Fahed, Akl C., Wang, Minxian, Patel, Aniruddh P., Ajufo, Ezimamaka, Maamari, Dimitri J., Aragam, Krishna G., Brockman, Deanna G., Vosburg, Trish, Ellinor, Patrick T., Ng, Kenney, Khera, Amit V.
Publicado 2022

Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass

por Khurshid, Shaan, Lazarte, Julieta, Pirruccello, James P., Weng, Lu-Chen, Choi, Seung Hoan, Hall, Amelia W., Wang, Xin, Friedman, Samuel F., Nauffal, Victor, Biddinger, Kiran J., Aragam, Krishna G., Batra, Puneet, Ho, Jennifer E., Philippakis, Anthony A., Ellinor, Patrick T., Lubitz, Steven A.
Publicado 2023

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

por Pirruccello, James P., Bick, Alexander, Wang, Minxian, Chaffin, Mark, Friedman, Samuel, Yao, Jie, Guo, Xiuqing, Venkatesh, Bharath Ambale, Taylor, Kent D., Post, Wendy S., Rich, Stephen, Lima, Joao A. C., Rotter, Jerome I., Philippakis, Anthony, Lubitz, Steven A., Ellinor, Patrick T., Khera, Amit V., Kathiresan, Sekar, Aragam, Krishna G.
Publicado 2020

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

por Jurgens, Sean J., Choi, Seung Hoan, Morrill, Valerie N., Chaffin, Mark, Pirruccello, James P., Halford, Jennifer L., Weng, Lu-Chen, Nauffal, Victor, Roselli, Carolina, Hall, Amelia W., Oetjens, Matthew T., Lagerman, Braxton, vanMaanen, David P., Aragam, Krishna G., Lunetta, Kathryn L., Haggerty, Christopher M., Lubitz, Steven A., Ellinor, Patrick T.
Publicado 2022

A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease

por Patel, Aniruddh P., Wang, Minxian, Ruan, Yunfeng, Koyama, Satoshi, Clarke, Shoa L., Yang, Xiong, Tcheandjieu, Catherine, Agrawal, Saaket, Fahed, Akl C., Ellinor, Patrick T., Tsao, Philip S., Sun, Yan V., Cho, Kelly, Wilson, Peter W. F., Assimes, Themistocles L., van Heel, David A., Butterworth, Adam S., Aragam, Krishna G., Natarajan, Pradeep, Khera, Amit V.
Publicado 2023

Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program

por Huang, Rose D. L., Nguyen, Xuan-Mai T., Peloso, Gina M., Trinder, Mark, Posner, Daniel C., Aragam, Krishna G., Ho, Yuk-Lam, Lynch, Julie A., Damrauer, Scott M., Chang, Kyong-Mi, Tsao, Philip S., Natarajan, Pradeep, Assimes, Themistocles, Gaziano, J. Michael, Djousse, Luc, Cho, Kelly, Wilson, Peter W. F., Huffman, Jennifer E., O’Donnell, Christopher J.
Publicado 2022

Common- and rare-variant genetic architecture of heart failure across the allele frequency spectrum

por Lee, David S.M., Cardone, Katie M., Zhang, David Y., Abramowitz, Sarah, DePaolo, John S., Aragam, Krishna G., Biddinger, Kiran, Conery, Mitchell, Dilitikas, Ozan, Hoffman-Andrews, Lily, Judy, Renae L., Khan, Atlas, Kulo, Iftikhar, Puckelwartz, Megan J., Reza, Nosheen, Satterfield, Benjamin A., Singhal, Pankhuri, Arany, Zoltan P., Cappola, Thomas P., Carruth, Eric, Day, Sharlene M., Do, Ron, Haggarty, Christopher M., Joseph, Jacob, McNally, Elizabeth, Nadkarni, Girish, Owens, Anjali T., Rader, Daniel J., Ritchie, Marylyn D., Sun, Yan, Voight, Benjamin F., Levin, Michael G., Damrauer, Scott M.
Publicado 2023

Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program

por Klarin, Derek, Devineni, Poornima, Sendamarai, Anoop K., Angueira, Anthony R., Graham, Sarah E., Shen, Ying H., Levin, Michael G., Pirruccello, James P., Surakka, Ida, Karnam, Purushotham R., Roychowdhury, Tanmoy, Li, Yanming, Wang, Minxian, Aragam, Krishna G., Paruchuri, Kaavya, Zuber, Verena, Shakt, Gabrielle E., Tsao, Noah L., Judy, Renae L., Vy, Ha My T., Verma, Shefali S., Rader, Daniel J., Do, Ron, Bavaria, Joseph E., Nadkarni, Girish N., Ritchie, Marylyn D., Burgess, Stephen, Guo, Dong-chuan, Ellinor, Patrick T., LeMaire, Scott A., Milewicz, Dianna M., Willer, Cristen J., Natarajan, Pradeep, Tsao, Philip S., Pyarajan, Saiju, Damrauer, Scott M.
Publicado 2023

Biological and clinical insights from genetics of insomnia symptoms

por Lane, Jacqueline M., Jones, Samuel E., Dashti, Hassan S., Wood, Andrew R., Aragam, Krishna G., van Hees, Vincent T., Strand, Linn B., Winsvold, Bendik S., Wang, Heming, Bowden, Jack, Song, Yanwei, Patel, Krunal, Anderson, Simon G., Beaumont, Robin N., Bechtold, David A., Cade, Brian E., Haas, Mary, Kathiresan, Sekar, Little, Max A., Luik, Annemarie I., Loudon, Andrew S., Purcell, Shaun, Richmond, Rebecca C., Scheer, Frank A. J. L., Schormair, Barbara, Tyrrell, Jessica, Winkelman, John W., Winkelmann, Juliane, Hveem, Kristian, Zhao, Chen, Nielsen, Jonas B., Willer, Cristen J., Redline, Susan, Spiegelhalder, Kai, Kyle, Simon D., Ray, David W., Zwart, John-Anker, Brumpton, Ben, Frayling, Timothy M., Lawlor, Deborah A., Rutter, Martin K., Weedon, Michael N., Saxena, Richa
Publicado 2019

Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure

por Levin, Michael G., Tsao, Noah L., Singhal, Pankhuri, Liu, Chang, Vy, Ha My T., Paranjpe, Ishan, Backman, Joshua D., Bellomo, Tiffany R., Bone, William P., Biddinger, Kiran J., Hui, Qin, Dikilitas, Ozan, Satterfield, Benjamin A., Yang, Yifan, Morley, Michael P., Bradford, Yuki, Burke, Megan, Reza, Nosheen, Charest, Brian, Judy, Renae L., Puckelwartz, Megan J., Hakonarson, Hakon, Khan, Atlas, Kottyan, Leah C., Kullo, Iftikhar, Luo, Yuan, McNally, Elizabeth M., Rasmussen-Torvik, Laura J., Day, Sharlene M., Do, Ron, Phillips, Lawrence S., Ellinor, Patrick T., Nadkarni, Girish N., Ritchie, Marylyn D., Arany, Zoltan, Cappola, Thomas P., Margulies, Kenneth B., Aragam, Krishna G., Haggerty, Christopher M., Joseph, Jacob, Sun, Yan V., Voight, Benjamin F., Damrauer, Scott M.
Publicado 2022