Targeting pre-mRNA splicing in cancers: roles, inhibitors, and therapeutic opportunities

por Araki, Shinsuke, Ohori, Momoko, Yugami, Masato
Publicado 2023

Secretory co-factors in next-generation cellular therapies for cancer

por Okuma, Atsushi, Ishida, Yoshihito, Kawara, Taketo, Hisada, Shoji, Araki, Shinsuke
Publicado 2022

Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors

por Murai, Aiko, Ebara, Shunsuke, Sasaki, Satoshi, Ohashi, Tomohiro, Miyazaki, Tohru, Nomura, Toshiyuki, Araki, Shinsuke
Publicado 2020

Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence

por Ohori, Momoko, Nakayama, Yusuke, Ogasawara-Shimizu, Mari, Toyoshiba, Hiroyoshi, Nakanishi, Atsushi, Aparicio, Samuel, Araki, Shinsuke
Publicado 2021

Inhibitors of CLK Protein Kinases Suppress Cell Growth and Induce Apoptosis by Modulating Pre-mRNA Splicing

por Araki, Shinsuke, Dairiki, Ryo, Nakayama, Yusuke, Murai, Aiko, Miyashita, Risa, Iwatani, Misa, Nomura, Toshiyuki, Nakanishi, Osamu
Publicado 2015

DNase γ Is the Effector Endonuclease for Internucleosomal DNA Fragmentation in Necrosis

por Mizuta, Ryushin, Araki, Shinsuke, Furukawa, Makoto, Furukawa, Yuki, Ebara, Syota, Shiokawa, Daisuke, Hayashi, Katsuhiko, Tanuma, Sei-ichi, Kitamura, Daisuke
Publicado 2013

Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation

por Mazloomian, Alborz, Araki, Shinsuke, Ohori, Momoko, El-Naggar, Amal M., Yap, Damian, Bashashati, Ali, Nakao, Shoichi, Sorensen, Poul H., Nakanishi, Atsushi, Shah, Sohrab, Aparicio, Samuel
Publicado 2019

CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor

por Funnell, Tyler, Tasaki, Shinya, Oloumi, Arusha, Araki, Shinsuke, Kong, Esther, Yap, Damian, Nakayama, Yusuke, Hughes, Christopher S., Cheng, S.-W. Grace, Tozaki, Hirokazu, Iwatani, Misa, Sasaki, Satoshi, Ohashi, Tomohiro, Miyazaki, Tohru, Morishita, Nao, Morishita, Daisuke, Ogasawara-Shimizu, Mari, Ohori, Momoko, Nakao, Shoichi, Karashima, Masatoshi, Sano, Masaya, Murai, Aiko, Nomura, Toshiyuki, Uchiyama, Noriko, Kawamoto, Tomohiro, Hara, Ryujiro, Nakanishi, Osamu, Shumansky, Karey, Rosner, Jamie, Wan, Adrian, McKinney, Steven, Morin, Gregg B., Nakanishi, Atsushi, Shah, Sohrab, Toyoshiba, Hiroyoshi, Aparicio, Samuel
Publicado 2017