Aβ Oligomer Toxicity-Reducing Therapy for the Prevention of Alzheimer’s Disease: Importance of the Nrf2 and PPARγ Pathways

por Araki, Wataru
Publicado 2023

Potential repurposing of oncology drugs for the treatment of Alzheimer's disease

por Araki, Wataru
Publicado 2013

EDITORIAL Meet Our Editorial Board Member

por Araki, Wataru
Publicado 2016

Reversibility of Aβ oligomer neurotoxicity

por Araki, Wataru
Publicado 2017

Protection against Amyloid-β Oligomer Neurotoxicity by Small Molecules with Antioxidative Properties: Potential for the Prevention of Alzheimer’s Disease Dementia

por Araki, Wataru, Kametani, Fuyuki
Publicado 2022

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons

por Mamada, Naomi, Tanokashira, Daisuke, Hosaka, Ai, Kametani, Fuyuki, Tamaoka, Akira, Araki, Wataru
Publicado 2015

Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant

por Motoki, Kazumi, Kume, Hideaki, Oda, Akiko, Tamaoka, Akira, Hosaka, Ai, Kametani, Fuyuki, Araki, Wataru
Publicado 2012

Chronic Cladribine Administration Increases Amyloid Beta Peptide Generation and Plaque Burden in Mice

por Hayes, Crystal D., Dey, Debleena, Palavicini, Juan Pablo, Wang, Hongjie, Araki, Wataru, Lakshmana, Madepalli K.
Publicado 2012

The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model

por Tanokashira, Daisuke, Mamada, Naomi, Yamamoto, Fumiko, Taniguchi, Kaori, Tamaoka, Akira, Lakshmana, Madepalli K., Araki, Wataru
Publicado 2017

LRP1 Downregulates the Alzheimer’s β-Secretase BACE1 by Modulating Its Intraneuronal Trafficking1,2,3

por Tanokashira, Daisuke, Motoki, Kazumi, Minegishi, Seiji, Hosaka, Ai, Mamada, Naomi, Tamaoka, Akira, Okada, Takashi, Lakshmana, Madepalli K., Araki, Wataru
Publicado 2015

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

por Amano, Akiko, Sanjo, Nobuo, Araki, Wataru, Anraku, Yasutaka, Nakakido, Makoto, Matsubara, Etsuro, Tomiyama, Takami, Nagata, Tetsuya, Tsumoto, Kouhei, Kataoka, Kazunori, Yokota, Takanori
Publicado 2023

Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders

por Araki, Wataru, Hattori, Kotaro, Kanemaru, Kazutomi, Yokoi, Yuma, Omachi, Yoshie, Takano, Harumasa, Sakata, Masuhiro, Yoshida, Sumiko, Tsukamoto, Tadashi, Murata, Miho, Saito, Yuko, Kunugi, Hiroshi, Goto, Yu-ichi, Nagaoka, Utako, Nagao, Masahiro, Komori, Takashi, Arima, Kunimasa, Ishii, Kenji, Murayama, Shigeo, Matsuda, Hiroshi, Tachimori, Hisateru, Araki, Yumiko M., Mizusawa, Hidehiro
Publicado 2017