Muscarinic receptors promote castration resistant growth of prostate cancer through a FAK-YAP signaling axis

por Goto, Yusuke, Ando, Toshinori, Izumi, Hiroki, Feng, Xiaodong, Arang, Nadia, Gilardi, Mara, Wang, Zhiyong, Ando, Kazuyo, Gutkind, J. Silvio
Publicado 2020

Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry

por Arang, Nadia, Lubrano, Simone, Rigiracciolo, Damiano Cosimo, Nachmanson, Daniela, Lippman, Scott M., Mali, Prashant, Harismendy, Olivier, Gutkind, J. Silvio
Publicado 2022

Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

por Arang, Nadia, Kain, Heather S., Glennon, Elizabeth K., Bello, Thomas, Dudgeon, Denali R., Walter, Emily N. F., Gujral, Taranjit S., Kaushansky, Alexis
Publicado 2017

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1

por Ando, Toshinori, Arang, Nadia, Wang, Zhiyong, Costea, Daniela Elena, Feng, Xiaodong, Goto, Yusuke, Izumi, Hiroki, Gilardi, Mara, Ando, Kazuyo, Gutkind, J. Silvio
Publicado 2021

Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)

por Rigiracciolo, Damiano Cosimo, Nohata, Nijiro, Lappano, Rosamaria, Cirillo, Francesca, Talia, Marianna, Adame-Garcia, Sendi Rafael, Arang, Nadia, Lubrano, Simone, De Francesco, Ernestina Marianna, Belfiore, Antonino, Gutkind, J. Silvio, Maggiolini, Marcello
Publicado 2022

Liver stage malaria infection is controlled by host regulators of lipid peroxidation

por Kain, Heather S., Glennon, Elizabeth K. K., Vijayan, Kamalakannan, Arang, Nadia, Douglass, Alyse N., Fortin, Chelsea L., Zuck, Meghan, Lewis, Adam J., Whiteside, Samantha L., Dudgeon, Denali R., Johnson, Jarrod S., Aderem, Alan, Stevens, Kelly R., Kaushansky, Alexis
Publicado 2019

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

por Arang, Nadia, Lubrano, Simone, Ceribelli, Michele, Rigiracciolo, Damiano C., Saddawi-Konefka, Robert, Faraji, Farhoud, Ramirez, Sydney I., Kim, Daehwan, Tosto, Frances A., Stevenson, Erica, Zhou, Yuan, Wang, Zhiyong, Bogomolovas, Julius, Molinolo, Alfredo A., Swaney, Danielle L., Krogan, Nevan J., Yang, Jing, Coma, Silvia, Pachter, Jonathan A., Aplin, Andrew E., Alessi, Dario R., Thomas, Craig J., Gutkind, J. Silvio
Publicado 2023