Novel subcellular localization for α-synuclein: possible functional consequences

por Guardia-Laguarta, Cristina, Area-Gomez, Estela, Schon, Eric A., Przedborski, Serge
Publicado 2015

Ethanol Induces Extracellular Vesicle Secretion by Altering Lipid Metabolism through the Mitochondria-Associated ER Membranes and Sphingomyelinases

por Ibáñez, Francesc, Montesinos, Jorge, Area-Gomez, Estela, Guerri, Consuelo, Pascual, María
Publicado 2021

Lipidomics study of plasma from patients suggest that ALS and PLS are part of a continuum of motor neuron disorders

por Area-Gomez, Estela, Larrea, D., Yun, T., Xu, Y., Hupf, J., Zandkarimi, F., Chan, R. B., Mitsumoto, H.
Publicado 2021

A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease

por Area-Gomez, Estela, de Groof, Ad, Bonilla, Eduardo, Montesinos, Jorge, Tanji, Kurenai, Boldogh, Istvan, Pon, Liza, Schon, Eric A.
Publicado 2018

ApoE4 upregulates the activity of mitochondria‐associated ER membranes

por Tambini, Marc D, Pera, Marta, Kanter, Ellen, Yang, Hua, Guardia‐Laguarta, Cristina, Holtzman, David, Sulzer, David, Area‐Gomez, Estela, Schon, Eric A
Publicado 2015

Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD)

por Agudelo, Christina W., Kumley, Britta K., Area-Gomez, Estela, Xu, Yimeng, Dabo, Abdoulaye J., Geraghty, Patrick, Campos, Michael, Foronjy, Robert, Garcia-Arcos, Itsaso
Publicado 2020

STIM1 Deficiency Leads to Specific Down-Regulation of ITPR3 in SH-SY5Y Cells

por Pascual-Caro, Carlos, Orantos-Aguilera, Yolanda, Sanchez-Lopez, Irene, de Juan-Sanz, Jaime, Parys, Jan B., Area-Gomez, Estela, Pozo-Guisado, Eulalia, Martin-Romero, Francisco Javier
Publicado 2020

Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice

por Miranda, André Miguel, Ashok, Archana, Chan, Robin Barry, Zhou, Bowen, Xu, Yimeng, McIntire, Laura Beth, Area-Gomez, Estela, Di Paolo, Gilbert, Duff, Karen E., Oliveira, Tiago Gil, Nuriel, Tal
Publicado 2022

Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease

por Chen, Jacinda, Soni, Rajesh Kumar, Xu, Yimeng, Simoes, Sabrina, Liang, Feng-Xia, DeFreitas, Laura, Hwang, Robert, Montesinos, Jorge, Lee, Joseph H., Area-Gomez, Estela, Nandakumar, Renu, Vardarajan, Badri, Marquer, Catherine
Publicado 2023

Lipid level alteration in human and cellular models of alpha synuclein mutations

por Avisar, Hila, Guardia-Laguarta, Cristina, Surface, Matthew, Papagiannakis, Nikos, Maniati, Matina, Antonellou, Roubina, Papadimitriou, Dimitra, Koros, Christos, Athanassiadou, Aglaia, Przedborski, Serge, Lerner, Boaz, Stefanis, Leonidas, Area-Gomez, Estela, Alcalay, Roy N.
Publicado 2022

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

por Area-Gomez, Estela, del Carmen Lara Castillo, Maria, Tambini, Marc D, Guardia-Laguarta, Cristina, de Groof, Ad J C, Madra, Moneek, Ikenouchi, Junichi, Umeda, Masato, Bird, Thomas D, Sturley, Stephen L, Schon, Eric A
Publicado 2012

Alzheimer’s-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury

por Agrawal, Rishi R., Larrea, Delfina, Xu, Yimeng, Shi, Lingyan, Zirpoli, Hylde, Cummins, Leslie G., Emmanuele, Valentina, Song, Donghui, Yun, Taekyung D., Macaluso, Frank P., Min, Wei, Kernie, Steven G., Deckelbaum, Richard J., Area-Gomez, Estela
Publicado 2022

The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking

por Montesinos, Jorge, Pera, Marta, Larrea, Delfina, Guardia‐Laguarta, Cristina, Agrawal, Rishi R, Velasco, Kevin R, Yun, Taekyung D, Stavrovskaya, Irina G, Xu, Yimeng, Koo, So Yeon, Snead, Amanda M, Sproul, Andrew A, Area‐Gomez, Estela
Publicado 2020

MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

por Larrea, Delfina, Pera, Marta, Gonnelli, Adriano, Quintana–Cabrera, Rubén, Akman, H Orhan, Guardia-Laguarta, Cristina, Velasco, Kevin R, Area-Gomez, Estela, Dal Bello, Federica, De Stefani, Diego, Horvath, Rita, Shy, Michael E, Schon, Eric A, Giacomello, Marta
Publicado 2019

BACE1 and SCD1 are associated with neurodegeneration

por Bedoya-Guzmán, Ferley A., Pacheco-Herrero, Mar, Salomon-Cruz, Ivan Daniel, Barrera-Sandoval, Angela Maria, Gutierrez Vargas, Johanna Andrea, Villamil-Ortiz, Javier Gustavo, Villegas Lanau, Carlos Andres, Arias-Londoño, Julián David, Area-Gomez, Estela, Cardona Gomez, Gloria Patricia
Publicado 2023

Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression

por Sol, Joaquim, Jové, Mariona, Povedano, Monica, Sproviero, William, Domínguez, Raul, Piñol-Ripoll, Gerard, Romero-Guevara, Ricardo, Hye, Abdul, Al-Chalabi, Ammar, Torres, Pascual, Andres-Benito, Pol, Area-Gómez, Estela, Pamplona, Reinald, Ferrer, Isidro, Ayala, Victòria, Portero-Otín, Manuel
Publicado 2021

Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPD

por Fan, Li-Chao, McConn, Keith, Plataki, Maria, Kenny, Sarah, Williams, Niamh C., Kim, Kihwan, Quirke, Jennifer A., Chen, Yan, Sauler, Maor, Möbius, Matthias E., Chung, Kuei-Pin, Area Gomez, Estela, Choi, Augustine M.K., Xu, Jin-Fu, Cloonan, Suzanne M.
Publicado 2023

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

por Area-Gomez, Estela, Larrea, Delfina, Pera, Marta, Agrawal, Rishi R., Guilfoyle, David N., Pirhaji, Leila, Shannon, Kathleen, Arain, Hirra A., Ashok, Archana, Chen, Qiuying, Dillman, Allissa A., Figueroa, Helen Y., Cookson, Mark R., Gross, Steven S., Fraenkel, Ernest, Duff, Karen E., Nuriel, Tal
Publicado 2020

RINT1 deficiency disrupts lipid metabolism and underlies a complex hereditary spastic paraplegia

por Launay, Nathalie, Ruiz, Montserrat, Planas-Serra, Laura, Verdura, Edgard, Rodríguez-Palmero, Agustí, Schlüter, Agatha, Goicoechea, Leire, Guilera, Cristina, Casas, Josefina, Campelo, Felix, Jouanguy, Emmanuelle, Casanova, Jean-Laurent, Boespflug-Tanguy, Odile, Vazquez Cancela, Maria, Gutiérrez-Solana, Luis González, Casasnovas, Carlos, Area-Gomez, Estela, Pujol, Aurora
Publicado 2023

Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity

por Planas-Serra, Laura, Launay, Nathalie, Goicoechea, Leire, Heron, Bénédicte, Jou, Cristina, Juliá-Palacios, Natalia, Ruiz, Montserrat, Fourcade, Stéphane, Casasnovas, Carlos, De La Torre, Carolina, Gelot, Antoinette, Marsal, Maria, Loza-Alvarez, Pablo, García-Cazorla, Àngels, Fatemi, Ali, Ferrer, Isidre, Portero-Otin, Manel, Area-Gómez, Estela, Pujol, Aurora
Publicado 2023