Study protocol for a multicentre randomised controlled trial: Safety, Tolerability, efficacy and quality of life Of a human recombinant alkaline Phosphatase in patients with sepsis...

por Peters, Esther, Mehta, Ravindra L, Murray, Patrick T, Hummel, Jürgen, Joannidis, Michael, Kellum, John A, Arend, Jacques, Pickkers, Peter
Publicado 2016

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

por Peters, Esther, Heuberger, Jules A. A. C., Tiessen, Renger, van Elsas, Andrea, Masereeuw, Rosalinde, Arend, Jacques, Stevens, Jasper, Pickkers, Peter
Publicado 2016

Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant h...

por Pickkers, Peter, Angus, Derek C, Arend, Jacques, Bellomo, Rinaldo, van den Berg, Erik, Bernholz, Juliane, Bestle, Morten, Broglio, Kristine, Carlsen, Jan, Doig, Christopher J, Ferrer, Ricard, Joannidis, Michael, Francois, Bruno, Doi, Kent, Kellum, John A, Laterre, Pierre-François, Liu, Kathleen, Mehta, Ravindra L, Murray, Patrick T, Ostermann, Marlies, Pettilä, Ville, Richards, Sharon, Young, Paul, Zarbock, Alexander, Kjølbye, Anne Louise
Publicado 2023