CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia

por Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S., Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W.
Publicado 2023

Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemia

por Schneider, Pauline, Crump, Nicholas T., Arentsen-Peters, Susan T.C.J.M., Smith, Alastair L., Hagelaar, Rico, Adriaanse, Fabienne R.S., Bos, Romy S., de Jong, Anja, Nierkens, Stefan, Koopmans, Bianca, Milne, Thomas A., Pieters, Rob, Stam, Ronald W.
Publicado 2023

Harnessing Gene Expression Profiles for the Identification of Ex Vivo Drug Response Genes in Pediatric Acute Myeloid Leukemia

por Cucchi, David G.J., Bachas, Costa, van den Heuvel-Eibrink, Marry M., Arentsen-Peters, Susan T.C.J.M., Kwidama, Zinia J., Schuurhuis, Gerrit J., Assaraf, Yehuda G., de Haas, Valérie, Kaspers, Gertjan J.L., Cloos, Jacqueline
Publicado 2020

High-Throughput Drug Library Screening in Primary KMT2A-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling

por Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Pinhanҫos, Sandra Mimoso, Koopmans, Bianca, Dolman, M. Emmy M., Jones, Luke, Garrido Castro, Patricia, Schneider, Pauline, Kerstjens, Mark, Molenaar, Jan J., Pieters, Rob, Zwaan, Christian Michel, Stam, Ronald W.
Publicado 2022

High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia

por Wander, Priscilla, Arentsen-Peters, Susan T.C.J.M., Pinhanҫos, Sandra S., Koopmans, Bianca, Dolman, M.Emmy M., Ariese, Rijndert, Bos, Frank L., Castro, Patricia Garrido, Jones, Luke, Schneider, Pauline, Navarro, Miriam Guillen, Molenaar, Jan J., Rios, Anne C., Zwaan, C. Michel, Stam, Ronald W.
Publicado 2021