Identification of Distant Drug Off-Targets by Direct Superposition of Binding Pocket Surfaces

por Schumann, Marcel, Armen, Roger S.
Publicado 2013

Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp1...

por Freidel, Matthew R., Armen, Roger S.
Publicado 2021

Modeling the Structure–Activity Relationship of Arbidol Derivatives and Other SARS-CoV-2 Fusion Inhibitors Targeting the S2 Segment of the Spike Protein

por Freidel, Matthew R., Armen, Roger S.
Publicado 2021

Mutation of Methionine to Asparagine but Not Leucine in Parathyroid Hormone Mimics the Loss of Biological Function upon Oxidation

por Gaur, Amit, Lipponen, Jessica, Yang, Yanmei, Armen, Roger S., Wang, Bin
Publicado 2022

Structural Implications for Selective Targeting of PARPs

por Steffen, Jamin D., Brody, Jonathan R., Armen, Roger S., Pascal, John M.
Publicado 2013

Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels

por Zhang, Miao, Pascal, John M., Schumann, Marcel, Armen, Roger S., Zhang, Ji-fang
Publicado 2012

LBMON186 Beta-agonist Profiling Reveals Novel Biased Signaling Phenotypes For The Beta 2-adrenergic Receptor With Implications In The Treatment Of Asthma

por Pascali, Francesco D, Ippolito, Michael, Wolfe, Emily, Komolov, Konstantin E, Hopfinger, Nathan, Lemenze, Douglas, Kim, Nicholas, Armen, Roger S, An, Steven S, Scott, Charles P, Benovic, Jeffrey L
Publicado 2022

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology

por Tsimberidou, Apostolia-Maria, Skliris, Antonis, Valentine, Alan, Shaw, Jamie, Hering, Ursula, Vo, Henry Hiep, Chan, Tung On, Armen, Roger S., Cottrell, Jeffrey R., Pan, Jen Q., Tsichlis, Philip N.
Publicado 2022