Targeting Chromatin Complexes in Myeloid Malignancies and Beyond: From Basic Mechanisms to Clinical Innovation

por Perner, Florian, Armstrong, Scott A.
Publicado 2020

iCanPlot: Visual Exploration of High-Throughput Omics Data Using Interactive Canvas Plotting

por Sinha, Amit U., Armstrong, Scott A.
Publicado 2012

Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention

por Uckelmann, Hannah J., Armstrong, Scott A.
Publicado 2020

eXframe: reusable framework for storage, analysis and visualization of genomics experiments

por Sinha, Amit U, Merrill, Emily, Armstrong, Scott A, Clark, Tim W, Das, Sudeshna
Publicado 2011

Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA

por Niizuma, Hidetaka, Searleman, Adam C., Takeda, Shugaku, Armstrong, Scott A., Park, Christopher Y., Cheng, Emily H., Hsieh, James J.
Publicado 2021

JMJD1C is required for the survival of acute myeloid leukemia by functioning as a coactivator for key transcription factors

por Chen, Mo, Zhu, Nan, Liu, Xiaochuan, Laurent, Benoit, Tang, Zhanyun, Eng, Rowena, Shi, Yang, Armstrong, Scott A., Roeder, Robert G.
Publicado 2015

miR-99 regulates normal and malignant hematopoietic stem cell self-renewal

por Khalaj, Mona, Woolthuis, Carolien M., Hu, Wenhuo, Durham, Benjamin H., Chu, S. Haihua, Qamar, Sarah, Armstrong, Scott A., Park, Christopher Y.
Publicado 2017

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors

por Lee, Dongjun, Sykes, Stephen M., Kalaitzidis, Demetrios, Lane, Andrew A., Kfoury, Youmna, Raaijmakers, Marc H.G.P., Wang, Ying-Hua, Armstrong, Scott A., Scadden, David T.
Publicado 2014

The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML

por Heidel, Florian H., Bullinger, Lars, Arreba-Tutusaus, Patricia, Wang, Zhu, Gaebel, Julia, Hirt, Carsten, Niederwieser, Dietger, Lane, Steven W., Döhner, Konstanze, Vasioukhin, Valera, Fischer, Thomas, Armstrong, Scott A.
Publicado 2013

Pathprinting: An integrative approach to understand the functional basis of disease

por Altschuler, Gabriel M, Hofmann, Oliver, Kalatskaya, Irina, Payne, Rebecca, Ho Sui, Shannan J, Saxena, Uma, Krivtsov, Andrei V, Armstrong, Scott A, Cai, Tianxi, Stein, Lincoln, Hide, Winston A
Publicado 2013

Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia

por Danis, Etienne, Yamauchi, Taylor, Echanique, Kristen, Zhang, Xi, Haladyna, Jessica N., Riedel, Simone S., Zhu, Nan, Xie, Huafeng, Orkin, Stuart H., Armstrong, Scott A., Bernt, Kathrin M., Neff, Tobias
Publicado 2016

Forward genetic screen of human transposase genomic rearrangements

por Henssen, Anton G., Jiang, Eileen, Zhuang, Jiali, Pinello, Luca, Socci, Nicholas D., Koche, Richard, Gonen, Mithat, Villasante, Camila M., Armstrong, Scott A., Bauer, Daniel E., Weng, Zhiping, Kentsis, Alex
Publicado 2016

Peptidomimetic blockade of MYB in acute myeloid leukemia

por Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex
Publicado 2018

Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia

por Hurtz, Christian, Chan, Lai N., Geng, Huimin, Ballabio, Erica, Xiao, Gang, Deb, Gauri, Khoury, Haytham, Chen, Chun-Wei, Armstrong, Scott A., Chen, Jianjun, Ernst, Patricia, Melnick, Ari, Milne, Thomas, Müschen, Markus
Publicado 2019

Chromatin modifying enzymes as modulators of reprogramming

por Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, Ogan. B., Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.
Publicado 2012

S125: NON-GENETIC RESISTANCE TO MENIN INHIBITION IN AML IS REVERSIBLE BY PERTURBATION OF KAT6A

por Perner, Florian, Rahnamoun, Homa, Wenge, Daniela V., Xiong, Yijun, Apazidis, Athina, Anand, Disha, Hatton, Charlie, Wen, Yanhe, Gu, Shengqing, Liu, X Shirley, Xiao, Wenbin, Cai, Sheng F., Levine, Ross L., Mcgeehan, Gerard M., Armstrong, Scott A.
Publicado 2023

Notch pathway activation targets AML-initiating cell homeostasis and differentiation

por Lobry, Camille, Ntziachristos, Panagiotis, Ndiaye-Lobry, Delphine, Oh, Philmo, Cimmino, Luisa, Zhu, Nan, Araldi, Elisa, Hu, Wenhuo, Freund, Jacquelyn, Abdel-Wahab, Omar, Ibrahim, Sherif, Skokos, Dimitris, Armstrong, Scott A., Levine, Ross L., Park, Christopher Y., Aifantis, Iannis
Publicado 2013

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

por Huang, Chun-Hao, Lujambio, Amaia, Zuber, Johannes, Tschaharganeh, Darjus F., Doran, Michael G., Evans, Michael J., Kitzing, Thomas, Zhu, Nan, de Stanchina, Elisa, Sawyers, Charles L., Armstrong, Scott A., Lewis, Jason S., Sherr, Charles J., Lowe, Scott W.
Publicado 2014

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia

por Casirati, Gabriele, Cosentino, Andrea, Mucci, Adele, Salah Mahmoud, Mohammed, Ugarte Zabala, Iratxe, Zeng, Jing, Ficarro, Scott B., Klatt, Denise, Brendel, Christian, Rambaldi, Alessandro, Ritz, Jerome, Marto, Jarrod A., Pellin, Danilo, Bauer, Daniel E., Armstrong, Scott A., Genovese, Pietro
Publicado 2023

Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement

por Yi, Joanna S., Federation, Alexander J., Qi, Jun, Dhe-Paganon, Sirano, Hadler, Michael, Xu, Xiang, St. Pierre, Roodolph, Varca, Anthony C., Wu, Lei, Marineau, Jason J., Smith, William B., Souza, Amanda, Chory, Emma J., Armstrong, Scott A., Bradner, James E.
Publicado 2014