Sialomucin CD43 Plays a Deleterious Role in the Development of Experimental Heart Failure Induced by Pressure Overload by Modulating Cardiac Inflammation and Fibrosis

por Kaur, Kuljeet, Velázquez, Francisco E., Anastasiou, Marina, Ngwenyama, Njabulo, Smolgovsky, Sasha, Aronovitz, Mark, Alcaide, Pilar
Publicado 2021

MicroRNA-Offset RNA Alters Gene Expression and Cell Proliferation

por Zhao, Jin, Schnitzler, Gavin R., Iyer, Lakshmanan K., Aronovitz, Mark J., Baur, Wendy E., Karas, Richard H.
Publicado 2016

Smooth muscle cell specific deletion of the PKGIα target RGS2 induces vascular dysfunction and hypertension

por Thoonen, Robrecht, Zhang, Haihua, Abe, Yuichi, Nickerson, Heather, Aronovitz, Mark, Chambon, Pierre, Karas, Richard H, Mendelsohn, Michael E
Publicado 2011

Mixed linage kinase 3 functions as a cGMP-dependent protein kinase I alpha substrate and regulates blood pressure and cardiac remodeling in vivo

por Calamaras, Timothy, Baumgartner, Robert, Wang, Guang-rong, Davis, Roger, Aronovitz, Mark, Kass, David, Karas, R, Blanton, Robert M
Publicado 2015

Protein kinase G I alpha activates an anti-remodeling signaling pathway in the heart via an interaction with the MAPKKK mixed lineage kinase 3

por Blanton, Robert M, Takimoto, Eiki, Lane, Angela, Aronovitz, Mark J, Karas, Richard H, Kass, David A, Mendelsohn, Michael E
Publicado 2011

Identification of protein kinase G I alpha interacting proteins as potential targets to prevent cardiac remodeling

por Blanton, Robert, Lane, Angela, Aronovitz, Mark, Wang, Guang-Rong, Thoonen, Robrecht, Davis, Roger, Mendelsohn, Michael, Kass, David, Karas, Richard
Publicado 2013

Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation

por Salvador, Ane M., Moss, M. Elizabeth, Aronovitz, Mark, Mueller, Kathleen B., Blanton, Robert M., Jaffe, Iris Z., Alcaide, Pilar
Publicado 2017

Short-Term Administration of Serelaxin Produces Predominantly Vascular Benefits in the Angiotensin II/L-NAME Chronic Heart Failure Model

por McCarthy, Joseph C., Aronovitz, Mark, DuPont, Jennifer J., Calamaras, Timothy D., Jaffe, Iris Z., Blanton, Robert M.
Publicado 2017

Th1 effector T cells selectively orchestrate cardiac fibrosis in nonischemic heart failure

por Nevers, Tania, Salvador, Ane M., Velazquez, Francisco, Ngwenyama, Njabulo, Carrillo-Salinas, Francisco J., Aronovitz, Mark, Blanton, Robert M., Alcaide, Pilar
Publicado 2017

Protein Kinase G Iα Inhibits Pressure Overload–Induced Cardiac Remodeling and Is Required for the Cardioprotective Effect of Sildenafil In Vivo

por Blanton, Robert M., Takimoto, Eiki, Lane, Angela M., Aronovitz, Mark, Piotrowski, Robert, Karas, Richard H., Kass, David A., Mendelsohn, Michael E.
Publicado 2012

Gut dysbiosis induced by cardiac pressure overload enhances adverse cardiac remodeling in a T cell-dependent manner

por Carrillo-Salinas, Francisco J, Anastasiou, Marina, Ngwenyama, Njabulo, Kaur, Kuljeet, Tai, Albert, Smolgovsky, Sasha A., Jetton, David, Aronovitz, Mark, Alcaide, Pilar
Publicado 2020

Deficiency of the Transcriptional Regulator p8 Results in Increased Autophagy and Apoptosis, and Causes Impaired Heart Function

por Kong, Derek K., Georgescu, Serban P., Cano, Carla, Aronovitz, Mark J., Iovanna, Juan Lucio, Patten, Richard D., Kyriakis, John M., Goruppi, Sandro
Publicado 2010

Targeted disruption of glycogen synthase kinase-3β in cardiomyocytes attenuates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice

por Zhang, Yali, Welzig, Charles M., Haburcak, Marian, Wang, Bo, Aronovitz, Mark, Blanton, Robert M., Park, Ho-Jin, Force, Thomas, Noujaim, Sami, Galper, Jonas B.
Publicado 2019

Intercellular Adhesion Molecule 1 Regulates Left Ventricular Leukocyte Infiltration, Cardiac Remodeling, and Function in Pressure Overload–Induced Heart Failure

por Salvador, Ane M., Nevers, Tania, Velázquez, Francisco, Aronovitz, Mark, Wang, Bonnie, Abadía Molina, Ana, Jaffe, Iris Z., Karas, Richard H., Blanton, Robert M., Alcaide, Pilar
Publicado 2016

Distinct Phenotypes Induced by Three Degrees of Transverse Aortic Constriction in Mice

por Richards, Daniel A., Aronovitz, Mark J., Calamaras, Timothy D., Tam, Kelly, Martin, Gregory L., Liu, Peiwen, Bowditch, Heather K., Zhang, Phyllis, Huggins, Gordon S., Blanton, Robert M.
Publicado 2019

Biventricular Remodeling in Murine Models of Right Ventricular Pressure Overload

por Kapur, Navin K., Paruchuri, Vikram, Aronovitz, Mark J., Qiao, Xiaoying, Mackey, Emily E., Daly, Gerard H., Ughreja, Kishan, Levine, Jonathan, Blanton, Robert, Hill, Nicholas S., Karas, Richard H.
Publicado 2013

Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A

por Ueda, Kazutaka, Takimoto, Eiki, Lu, Qing, Liu, Pangyen, Fukuma, Nobuaki, Adachi, Yusuke, Suzuki, Ryo, Chou, Shengpu, Baur, Wendy, Aronovitz, Mark J., Greenberg, Andrew S., Komuro, Issei, Karas, Richard H.
Publicado 2018

Direct Regulation of Blood Pressure by Smooth Muscle Cell Mineralocorticoid Receptors

por McCurley, Amy, Pires, Paulo W., Bender, Shawn B., Aronovitz, Mark, Zhao, Michelle J., Metzger, Daniel, Chambon, Pierre, Hill, Michael A., Dorrance, Anne M., Mendelsohn, Michael E., Jaffe, Iris Z.
Publicado 2012

Glycogen Synthase Kinase-3β Inhibition Ameliorates Cardiac Parasympathetic Dysfunction in Type 1 Diabetic Akita Mice

por Zhang, Yali, Welzig, Charles M., Picard, Kristen L., Du, Chuang, Wang, Bo, Pan, Jen Q., Kyriakis, John M., Aronovitz, Mark J., Claycomb, William C., Blanton, Robert M., Park, Ho-Jin, Galper, Jonas B.
Publicado 2014

Reducing Endoglin Activity Limits Calcineurin and TRPC‐6 Expression and Improves Survival in a Mouse Model of Right Ventricular Pressure Overload

por Kapur, Navin K., Qiao, Xiaoying, Paruchuri, Vikram, Mackey, Emily E., Daly, Gerard H., Ughreja, Keshan, Morine, Kevin J., Levine, Jonathan, Aronovitz, Mark J., Hill, Nicholas S., Jaffe, Iris Z., Letarte, Michelle, Karas, Richard H.
Publicado 2014