Hsp70 inhibition induces myeloma cell death via the intracellular accumulation of immunoglobulin and the generation of proteotoxic stress()

por Zhang, Lei, Fok, Jacqueline J.L., Mirabella, Fabio, Aronson, Lauren I., Fryer, Rosemary A., Workman, Paul, Morgan, Gareth J., Davies, Faith E.
Publicado 2013

The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway

por Smith, Emma M., Zhang, Lei, Walker, Brian A., Davenport, Emma L., Aronson, Lauren I., Krige, David, Hooftman, Leon, Drummond, Alan H., Morgan, Gareth J., Davies, Faith E.
Publicado 2013

A Novel Functional Role for MMSET in RNA Processing Based on the Link Between the REIIBP Isoform and Its Interaction with the SMN Complex

por Mirabella, Fabio, Murison, Alexander, Aronson, Lauren I., Wardell, Christopher P., Thompson, Andrew J., Hanrahan, Sarah J., Fok, Jacqueline H. L., Pawlyn, Charlotte, Kaiser, Martin F., Walker, Brian A., Davies, Faith E., Morgan, Gareth J.
Publicado 2014

SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance

por Llorca-Cardenosa, Marta J., Aronson, Lauren I., Krastev, Dragomir B., Nieminuszczy, Jadwiga, Alexander, John, Song, Feifei, Dylewska, Malgorzata, Broderick, Ronan, Brough, Rachel, Zimmermann, Astrid, Zenke, Frank T., Gurel, Bora, Riisnaes, Ruth, Ferreira, Ana, Roumeliotis, Theodoros, Choudhary, Jyoti, Pettitt, Stephen J., de Bono, Johann, Cervantes, Andres, Haider, Syed, Niedzwiedz, Wojciech, Lord, Christopher J., Chong, Irene Y.
Publicado 2022