Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology

por Arrázola, Macarena S., Court, Felipe A.
Publicado 2019

Commentary on “PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons”

por Arrázola, Macarena S., Court, Felipe A.
Publicado 2022

How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario

por Arrázola, Macarena S., Silva-Alvarez, Carmen, Inestrosa, Nibaldo C.
Publicado 2015

Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons

por Arrázola, Macarena S., Ramos-Fernández, Eva, Cisternas, Pedro, Ordenes, Daniela, Inestrosa, Nibaldo C.
Publicado 2017

Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics

por Silva-Alvarez, Carmen, Arrázola, Macarena S., Godoy, Juan A., Ordenes, Daniela, Inestrosa, Nibaldo C.
Publicado 2013

Hormetic-Like Effects of L-Homocysteine on Synaptic Structure, Function, and Aβ Aggregation

por Montecinos-Oliva, Carla, Arrázola, Macarena S., Jara, Claudia, Tapia-Rojas, Cheril, Inestrosa, Nibaldo C.
Publicado 2020

Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease

por Dinamarca, Margarita C, Sagal, Juan P, Quintanilla, Rodrigo A, Godoy, Juan A, Arrázola, Macarena S, Inestrosa, Nibaldo C
Publicado 2010

Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase

por Ramos-Fernández, Eva, Arrázola, Macarena S., Oliva, Carolina A., Arredondo, Sebastián B., Varela-Nallar, Lorena, Inestrosa, Nibaldo C.
Publicado 2021

Genetic background modulates phenotypic expressivity in OPA1 mutated mice, relevance to DOA pathogenesis

por Atamena, Djamaa, Gurram, Venu, Petsophonsakul, Petnoï, Khosrobakhsh, Farnoosh, Arrázola, Macarena S., Botella, Marlène, Wissinger, Bernd, Szelechowski, Marion, Belenguer, Pascale
Publicado 2023

Poly(ethylene imine)-chitosan carbon dots: study of its physical–chemical properties and biological in vitro performance

por Santos, Nicolás, Valenzuela, Santiago, Segura, Camilo, Osorio-Roman, Igor, Arrázola, Macarena S., Panadero-Medianero, Concepción, Santana, Paula A., Ahumada, Manuel
Publicado 2023

Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment i...

por Tapia-Rojas, Cheril, Lindsay, Carolina B., Montecinos-Oliva, Carla, Arrazola, Macarena S., Retamales, Rocio M., Bunout, Daniel, Hirsch, Sandra, Inestrosa, Nibaldo C.
Publicado 2015

The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling

por Chao de la Barca, Juan Manuel, Arrázola, Macarena S., Bocca, Cinzia, Arnauné-Pelloquin, Laetitia, Iuliano, Olga, Tcherkez, Guillaume, Lenaers, Guy, Simard, Gilles, Belenguer, Pascale, Reynier, Pascal
Publicado 2019

Mitochondrial OPA1 Deficiency Is Associated to Reversible Defects in Spatial Memory Related to Adult Neurogenesis in Mice

por Andraini, Trinovita, Moulédous, Lionel, Petsophonsakul, Petnoi, Florian, Cédrick, Gauzin, Sébastien, Botella-Daloyau, Marlène, Arrázola, Macarena, Nikolla, Kamela, Philip, Adam, Leydier, Alice, Marque, Manon, Arnauné-Pelloquin, Laetitia, Belenguer, Pascale, Rampon, Claire, Miquel, Marie-Christine
Publicado 2023

Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation

por Arrázola, Macarena S., Lira, Matías, Véliz‐Valverde, Felipe, Quiroz, Gabriel, Iqbal, Somya, Eaton, Samantha L., Lamont, Douglas J., Huerta, Hernán, Ureta, Gonzalo, Bernales, Sebastián, Cárdenas, J. César, Cerpa, Waldo, Wishart, Thomas M., Court, Felipe A.
Publicado 2023