Immunotherapies against HER2-Positive Breast Cancer

por Duro-Sánchez, Santiago, Alonso, Macarena Román, Arribas, Joaquín
Publicado 2023

Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence

por Morancho, Beatriz, Martínez-Barriocanal, Águeda, Villanueva, Josep, Arribas, Joaquín
Publicado 2015

Protocol to generate a patient derived xenograft model of acquired resistance to immunotherapy in humanized mice

por Martínez-Sabadell, Alex, Ovejero Romero, Pablo, Arribas, Joaquín, Arenas, Enrique J.
Publicado 2022

Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis

por Martín-Pérez, Rosa, Yerbes, Rosario, Mora-Molina, Rocío, Cano-González, Ana, Arribas, Joaquín, Mazzone, Massimiliano, López-Rivas, Abelardo, Palacios, Carmen
Publicado 2017

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts

por Morancho, Beatriz, Zacarías-Fluck, Mariano, Esgueva, Antonio, Bernadó-Morales, Cristina, Cosimo, Serena Di, Prat, Aleix, Cortés, Javier, Arribas, Joaquín, Rubio, Isabel T.
Publicado 2016

HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503

por Gorbatenko, Andrej, Søkilde, Rolf, Sorensen, Ester E., Newie, Inga, Persson, Helena, Morancho, Beatriz, Arribas, Joaquin, Litman, Thomas, Rovira, Carlos, Pedersen, Stine Falsig
Publicado 2019

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

por Chandarlapaty, Sarat, Scaltriti, Maurizio, Angelini, Pierdavide, Ye, Qing, Guzman, Marta, Hudis, Clifford A., Norton, Larry, Solit, David B., Arribas, Joaquin, Baselga, Jose, Rosen, Neal
Publicado 2009

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns

por Mateo, Lidia, Duran-Frigola, Miquel, Gris-Oliver, Albert, Palafox, Marta, Scaltriti, Maurizio, Razavi, Pedram, Chandarlapaty, Sarat, Arribas, Joaquin, Bellet, Meritxell, Serra, Violeta, Aloy, Patrick
Publicado 2020

Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation

por Arenas, Enrique J., Martínez-Sabadell, Alex, Rius Ruiz, Irene, Román Alonso, Macarena, Escorihuela, Marta, Luque, Antonio, Fajardo, Carlos Alberto, Gros, Alena, Klein, Christian, Arribas, Joaquín
Publicado 2021

Silencing of adaptor protein SH3BP2 reduces KIT/PDGFRA receptors expression and impairs gastrointestinal stromal tumors growth

por Serrano‐Candelas, Eva, Ainsua‐Enrich, Erola, Navinés‐Ferrer, Arnau, Rodrigues, Paulo, García‐Valverde, Alfonso, Bazzocco, Sarah, Macaya, Irati, Arribas, Joaquín, Serrano, César, Sayós, Joan, Arango, Diego, Martin, Margarita
Publicado 2018

Evaluation of triple negative breast cancer with heterogeneous immune infiltration

por Quintana, Ángela, Arenas, Enrique Javier, Bernadó, Cristina, Navarro, José Fernández, González, Jonatan, Esteve-Codina, Anna, Moliné, Teresa, Marti, Merce, Curigliano, Giuseppe, Schmid, Peter, Peg, Vicente, Arribas, Joaquín, Cortés, Javier
Publicado 2023

Epstein–Barr Virus+ B Cells in Breast Cancer Immune Response: A Case Report

por Aran, Andrea, Peg, Vicente, Rabanal, Rosa Maria, Bernadó, Cristina, Zamora, Esther, Molina, Elisa, Arribas, Yago A., Arribas, Joaquín, Pérez, José, Roura-Mir, Carme, Carrascal, Montserrat, Cortés, Javier, Martí, Mercè
Publicado 2021

GDF15 Is an Eribulin Response Biomarker also Required for Survival of DTP Breast Cancer Cells

por Bellio, Chiara, Emperador, Marta, Castellano, Pol, Gris-Oliver, Albert, Canals, Francesc, Sánchez-Pla, Alex, Zamora, Esther, Arribas, Joaquín, Saura, Cristina, Serra, Violeta, Tabernero, Josep, Littlefield, Bruce A., Villanueva, Josep
Publicado 2022

The Second Generation Antibody-Drug Conjugate SYD985 Overcomes Resistances to T-DM1

por Nadal-Serrano, Mercedes, Morancho, Beatriz, Escrivá-de-Romaní, Santiago, Bernadó Morales, Cristina, Luque, Antonio, Escorihuela, Marta, Espinosa Bravo, Martín, Peg, Vicente, Dijcks, Fred A., Dokter, Wim H.A., Cortés, Javier, Saura, Cristina, Arribas, Joaquín
Publicado 2020

Antitumor activity of the PI3K δ-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer

por Fiascarelli, Alessio, Merlino, Giuseppe, Capano, Stefania, Talucci, Simone, Bisignano, Diego, Bressan, Alessandro, Bellarosa, Daniela, Carrisi, Corrado, Paoli, Alessandro, Bigioni, Mario, Tunici, Patrizia, Irrissuto, Clelia, Salerno, Massimiliano, Arribas, Joaquin, de Stanchina, Elisa, Scaltriti, Maurizio, Binaschi, Monica
Publicado 2023

High HER2 protein levels correlate with increased survival in breast cancer patients treated with anti‐HER2 therapy

por Nuciforo, Paolo, Thyparambil, Sheeno, Aura, Claudia, Garrido-Castro, Ana, Vilaro, Marta, Peg, Vicente, Jimenez, José, Vicario, Rocio, Cecchi, Fabiola, Hoos, William, Burrows, Jon, Hembrough, Todd, Ferreres, Juan Carles, Perez-Garcia, José, Arribas, Joaquin, Cortes, Javier, Scaltriti, Maurizio
Publicado 2015

HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway

por Smith, Alison E., Ferraro, Emanuela, Safonov, Anton, Morales, Cristina Bernado, Lahuerta, Enrique J. Arenas, Li, Qing, Kulick, Amanda, Ross, Dara, Solit, David B., de Stanchina, Elisa, Reis-Filho, Jorge, Rosen, Neal, Arribas, Joaquín, Razavi, Pedram, Chandarlapaty, Sarat
Publicado 2021

Patterns of HER2 Gene Amplification and Response to Anti-HER2 Therapies

por Vicario, Rocio, Peg, Vicente, Morancho, Beatriz, Zacarias-Fluck, Mariano, Zhang, Junjie, Martínez-Barriocanal, Águeda, Navarro Jiménez, Alexandra, Aura, Claudia, Burgues, Octavio, Lluch, Ana, Cortés, Javier, Nuciforo, Paolo, Rubio, Isabel T., Marangoni, Elisabetta, Deeds, James, Boehm, Markus, Schlegel, Robert, Tabernero, Josep, Mosher, Rebecca, Arribas, Joaquín
Publicado 2015

Overview of virus and cancer relationships. Position paper

por Bouza, Emilio, Jiménez, Miguel Martín, Alemany, Laia, Arribas, Joaquín, Bañares, Rafael, Barragán, Mª Begoña, Bouza, José María Eiros, Felip, Enriqueta, Fernández-Capetillo, Oscar, Gracia, Diego, López-Vélez, Rogelio, Mollar, Juan Bautista, Muñoz, Patricia, Paz-Ares, Luis, Torné, Aureli, Tovar, Javier, Valencia, Eulalia, Palomo, Esteban
Publicado 2021

Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors

por Serrano, César, Vivancos, Ana, López-Pousa, Antonio, Matito, Judit, Mancuso, Francesco M., Valverde, Claudia, Quiroga, Sergi, Landolfi, Stefania, Castro, Sandra, Dopazo, Cristina, Sebio, Ana, Virgili, Anna C., Menso, María M., Martín-Broto, Javier, Sansó, Miriam, García-Valverde, Alfonso, Rosell, Jordi, Fletcher, Jonathan A., George, Suzanne, Carles, Joan, Arribas, Joaquín
Publicado 2020