Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation

por Dong, Cheng, Zhang, Heng, Xu, Chao, Arrowsmith, Cheryl H., Min, Jinrong
Publicado 2014

Biophysical characterization of recombinant proteins: A key to higher structural genomics success

por Vedadi, Masoud, Arrowsmith, Cheryl H., Allali-Hassani, Abdellah, Senisterra, Guillermo, Wasney, Gregory A.
Publicado 2010

A global assessment of cancer genomic alterations in epigenetic mechanisms

por Shah, Muhammad A, Denton, Emily L, Arrowsmith, Cheryl H, Lupien, Mathieu, Schapira, Matthieu
Publicado 2014

Targeting human SET1/MLL family of proteins

por Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Publicado 2017

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition

por Halabelian, Levon, Ravichandran, Mani, Li, Yanjun, Zeng, Hong, Rao, Anjana, Aravind, L., Arrowsmith, Cheryl H
Publicado 2019

The SMX DNA Repair Tri-nuclease

por Wyatt, Haley D.M., Laister, Rob C., Martin, Stephen R., Arrowsmith, Cheryl H., West, Stephen C.
Publicado 2017

The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme

por Bhandari, Vaibhav, Reichheld, Sean E., Houliston, Scott, Lemak, Alexander, Arrowsmith, Cheryl H., Sharpe, Simon, Houry, Walid A.
Publicado 2023

The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface

por Guegueniat, Julia, Halabelian, Levon, Zeng, Hong, Dong, Aiping, Li, Yanjun, Wu, Hong, Arrowsmith, Cheryl H, Kothe, Ute
Publicado 2021

Solution NMR Structure of Hypothetical Protein CV_2116 Encoded by a Viral Prophage Element in Chromobacterium violaceum

por Yang, Yunhuang, Ramelot, Theresa A., Cort, John R., Garcia, Maite, Yee, Adelinda, Arrowsmith, Cheryl H., Kennedy, Michael A.
Publicado 2012

Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei

por MacDonald, Kate M., Nicholson-Puthenveedu, Shirony, Tageldein, Maha M., Khasnis, Sarika, Arrowsmith, Cheryl H., Harding, Shane M.
Publicado 2023

Solution NMR Structure and Histone Binding of the PHD Domain of Human MLL5

por Lemak, Alexander, Yee, Adelinda, Wu, Hong, Yap, Damian, Zeng, Hong, Dombrovski, Ludmila, Houliston, Scott, Aparicio, Samuel, Arrowsmith, Cheryl H.
Publicado 2013

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

por Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Publicado 2016

DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models

por Kagoya, Yuki, Nakatsugawa, Munehide, Saso, Kayoko, Guo, Tingxi, Anczurowski, Mark, Wang, Chung-Hsi, Butler, Marcus O., Arrowsmith, Cheryl H., Hirano, Naoto
Publicado 2018

Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini

por Ouyang, Hui, Ali, Yousuf O., Ravichandran, Mani, Dong, Aiping, Qiu, Wei, MacKenzie, Farrell, Dhe-Paganon, Sirano, Arrowsmith, Cheryl H., Zhai, R. Grace
Publicado 2012

Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation

por Kim, Tae-Eun, Tsuboyama, Kotaro, Houliston, Scott, Martell, Cydney M., Phoumyvong, Claire M., Lemak, Alexander, Haddox, Hugh K., Arrowsmith, Cheryl H., Rocklin, Gabriel J.
Publicado 2022

Recognition and Specificity Determinants of the Human Cbx Chromodomains

por Kaustov, Lilia, Ouyang, Hui, Amaya, Maria, Lemak, Alexander, Nady, Nataliya, Duan, Shili, Wasney, Gregory A., Li, Zhihong, Vedadi, Masoud, Schapira, Matthieu, Min, Jinrong, Arrowsmith, Cheryl H.
Publicado 2011

Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding

por Andresen, Cecilia, Helander, Sara, Lemak, Alexander, Farès, Christophe, Csizmok, Veronika, Carlsson, Jonas, Penn, Linda Z., Forman-Kay, Julie D., Arrowsmith, Cheryl H., Lundström, Patrik, Sunnerhagen, Maria
Publicado 2012

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

por Wu, Hong, Zeng, Hong, Dong, Aiping, Li, Fengling, He, Hao, Senisterra, Guillermo, Seitova, Alma, Duan, Shili, Brown, Peter J., Vedadi, Masoud, Arrowsmith, Cheryl H., Schapira, Matthieu
Publicado 2013

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment

por Criqui, Mélanie, Qamra, Aditi, Chu, Tsz Wai, Sharma, Monika, Tsao, Julissa, Henry, Danielle A, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H, Winegarden, Neil, Lupien, Mathieu, Harrington, Lea
Publicado 2020

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

por Szewczyk, Magdalena M., Luciani, Genna M., Vu, Victoria, Murison, Alex, Dilworth, David, Barghout, Samir H., Lupien, Mathieu, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia
Publicado 2022