Emerging concepts in the science of vaccine adjuvants

por Pulendran, Bali, S. Arunachalam, Prabhu, O’Hagan, Derek T.
Publicado 2021

Toll-Like Receptor 9 Activation Rescues Impaired Antibody Response in Needle-free Intradermal DNA Vaccination

por Arunachalam, Prabhu S., Mishra, Ria, Badarinath, Krithika, Selvam, Deepak, Payeli, Sravan K., Stout, Richard R., Ranga, Udaykumar
Publicado 2016

A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice

por Lee, Audrey, Scott, Madeleine K. D., Wimmers, Florian, Arunachalam, Prabhu S., Luo, Wei, Fox, Christopher B., Tomai, Mark, Khatri, Purvesh, Pulendran, Bali
Publicado 2022

The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection

por Charles, Tysheena P., Burton, Samantha L., Arunachalam, Prabhu S., Cottrell, Christopher A., Sewall, Leigh M., Bollimpelli, Venkata S., Gangadhara, Sailaja, Dey, Antu K., Ward, Andrew B., Shaw, George M., Hunter, Eric, Amara, Rama R., Pulendran, Bali, van Gils, Marit J., Derdeyn, Cynthia A.
Publicado 2021

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

por Weidenbacher, Payton A.-B., Sanyal, Mrinmoy, Friedland, Natalia, Tang, Shaogeng, Arunachalam, Prabhu S., Hu, Mengyun, Kumru, Ozan S., Morris, Mary Kate, Fontenot, Jane, Shirreff, Lisa, Do, Jonathan, Cheng, Ya-Chen, Vasudevan, Gayathri, Feinberg, Mark B., Villinger, Francois J., Hanson, Carl, Joshi, Sangeeta B., Volkin, David B., Pulendran, Bali, Kim, Peter S.
Publicado 2023

Durability of immune responses to mRNA booster vaccination against COVID-19

por Arunachalam, Prabhu S., Lai, Lilin, Samaha, Hady, Feng, Yupeng, Hu, Mengyun, Hui, Harold Sai-yin, Wali, Bushra, Ellis, Madison, Davis-Gardner, Meredith E., Huerta, Christopher, Bechnak, Kareem, Bechnak, Sarah, Lee, Matthew, Litvack, Matthew B., Losada, Cecilia, Grifoni, Alba, Sette, Alessandro, Zarnitsyna, Veronika I., Rouphael, Nadine, Suthar, Mehul S., Pulendran, Bali
Publicado 2023

Author Correction: A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

por Weidenbacher, Payton A.-B., Sanyal, Mrinmoy, Friedland, Natalia, Tang, Shaogeng, Arunachalam, Prabhu S., Hu, Mengyun, Kumru, Ozan S., Morris, Mary Kate, Fontenot, Jane, Shirreff, Lisa, Do, Jonathan, Cheng, Ya-Chen, Vasudevan, Gayathri, Feinberg, Mark B., Villinger, Francois J., Hanson, Carl, Joshi, Sangeeta B., Volkin, David B., Pulendran, Bali, Kim, Peter S.
Publicado 2023

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

por Weidenbacher, Payton A.-B., Sanyal, Mrinmoy, Friedland, Natalia, Tang, Shaogeng, Arunachalam, Prabhu S., Hu, Mengyun, Kumru, Ozan S., Morris, Mary Kate, Fontenot, Jane, Shirreff, Lisa, Do, Jonathan, Cheng, Ya-Chen, Vasudevan, Gayathri, Feinberg, Mark B., Villinger, Francois J., Hanson, Carl, Joshi, Sangeeta B., Volkin, David B., Pulendran, Bali, Kim, Peter S.
Publicado 2022

Early immune responses have long-term associations with clinical, virologic, and immunologic outcomes in patients with COVID-19

por Hu, Zicheng, van der Ploeg, Kattria, Chakraborty, Saborni, Arunachalam, Prabhu, Mori, Diego, Jacobson, Karen, Bonilla, Hector, Parsonnet, Julie, Andrews, Jason, Hedlin, Haley, de la Parte, Lauren, Dantzler, Kathleen, Ty, Maureen, Tan, Gene, Blish, Catherine, Takahashi, Saki, Rodriguez-Barraquer, Isabel, Greenhouse, Bryan, Butte, Atul, Singh, Upinder, Pulendran, Bali, Wang, Taia, Jagannathan, Prasanna
Publicado 2022

mRNA vaccination compared to infection elicits an IgG-predominant response with greater SARS-CoV-2 specificity and similar decrease in variant spike recognition

por Röltgen, Katharina, Nielsen, Sandra C. A., Arunachalam, Prabhu S., Yang, Fan, Hoh, Ramona A., Wirz, Oliver F., Lee, Alexandra S., Gao, Fei, Mallajosyula, Vamsee, Li, Chunfeng, Haraguchi, Emily, Shoura, Massa J., Wilbur, James L., Wohlstadter, Jacob N., Davis, Mark M., Pinsky, Benjamin A., Sigal, George B., Pulendran, Bali, Nadeau, Kari C., Boyd, Scott D.
Publicado 2021

Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in non...

por Pillet, Stéphane, Arunachalam, Prabhu S., Andreani, Guadalupe, Golden, Nadia, Fontenot, Jane, Aye, Pyone Pyone, Röltgen, Katharina, Lehmicke, Gabrielle, Gobeil, Philipe, Dubé, Charlotte, Trépanier, Sonia, Charland, Nathalie, D’Aoust, Marc-André, Russell-Lodrigue, Kasi, Monjure, Christopher, Blair, Robert V., Boyd, Scott D., Bohm, Rudolf P., Rappaport, Jay, Villinger, François, Landry, Nathalie, Pulendran, Bali, Ward, Brian J.
Publicado 2022

Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses

por Sievers, Benjamin L., Chakraborty, Saborni, Xue, Yong, Gelbart, Terri, Gonzalez, Joseph C., Cassidy, Arianna G., Golan, Yarden, Prahl, Mary, Gaw, Stephanie L., Arunachalam, Prabhu S., Blish, Catherine A., Boyd, Scott D., Davis, Mark M., Jagannathan, Prasanna, Nadeau, Kari C., Pulendran, Bali, Singh, Upinder, Scheuermann, Richard H., Frieman, Matthew B., Vashee, Sanjay, Wang, Taia T., Tan, Gene S.
Publicado 2022

Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine

por Li, Chunfeng, Lee, Audrey, Grigoryan, Lilit, Arunachalam, Prabhu S., Scott, Madeleine K. D., Trisal, Meera, Wimmers, Florian, Sanyal, Mrinmoy, Weidenbacher, Payton A., Feng, Yupeng, Adamska, Julia Z., Valore, Erika, Wang, Yanli, Verma, Rohit, Reis, Noah, Dunham, Diane, O’Hara, Ruth, Park, Helen, Luo, Wei, Gitlin, Alexander D., Kim, Peter, Khatri, Purvesh, Nadeau, Kari C., Pulendran, Bali
Publicado 2022

Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multi-omics study

por Hu, Zicheng, van der Ploeg, Kattria, Chakraborty, Saborni, Arunachalam, Prabhu S, Mori, Diego AM, Jacobson, Karen B, Bonilla, Hector, Parsonnet, Julie, Andrews, Jason R, Holubar, Marisa, Subramanian, Aruna, Khosla, Chaitan, Maldonado, Yvonne, Hedlin, Haley, de la Parte, Lauren, Press, Kathleen, Ty, Maureen, Tan, Gene S, Blish, Catherine, Takahashi, Saki, Rodriguez-Barraquer, Isabel, Greenhouse, Bryan, Butte, Atul J, Singh, Upinder, Pulendran, Bali, Wang, Taia T, Jagannathan, Prasanna
Publicado 2022

Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8(+) T cell responses post SARS-CoV-2 infection

por Gao, Fei, Mallajoysula, Vamsee, Arunachalam, Prabhu S., van der Ploeg, Kattria, Manohar, Monali, Röltgen, Katharina, Yang, Fan, Wirz, Oliver, Hoh, Ramona, Haraguchi, Emily, Lee, Ji-Yeun, Willis, Richard, Ramachandiran, Vasanthi, Li, Jiefu, Kathuria, Karan Raj, Li, Chunfeng, Lee, Alexandra S., Shah, Mihir M., Sindher, Sayantani B., Gonzalez, Joseph, Altman, John D., Wang, Taia T., Boyd, Scott D., Pulendran, Bali, Jagannathan, Prasanna, Nadeau, Kari C., Davis, Mark.M.
Publicado 2023

Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice

por Grigoryan, Lilit, Lee, Audrey, Walls, Alexandra C., Lai, Lilin, Franco, Benjamin, Arunachalam, Prabhu S., Feng, Yupeng, Luo, Wei, Vanderheiden, Abigail, Floyd, Katharine, Wrenn, Samuel, Pettie, Deleah, Miranda, Marcos C., Kepl, Elizabeth, Ravichandran, Rashmi, Sydeman, Claire, Brunette, Natalie, Murphy, Michael, Fiala, Brooke, Carter, Lauren, Coffman, Robert L., Novack, David, Kleanthous, Harry, O’Hagan, Derek T., van der Most, Robbert, McLellan, Jason S., Suthar, Mehul, Veesler, David, King, Neil P., Pulendran, Bali
Publicado 2022

Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice

por Walls, Alexandra C., VanBlargan, Laura A., Wu, Kai, Choi, Angela, Navarro, Mary Jane, Lee, Diana, Avena, Laura, Berrueta, Daniela Montes, Pham, Minh N., Elbashir, Sayda, Kraft, John C., Miranda, Marcos C., Kepl, Elizabeth, Johnson, Max, Blackstone, Alyssa, Sprouse, Kaitlin, Fiala, Brooke, O’Connor, Megan A., Brunette, Natalie, Arunachalam, Prabhu S., Shirreff, Lisa, Rogers, Kenneth, Carter, Lauren, Fuller, Deborah H., Villinger, Francois, Pulendran, Bali, Diamond, Michael S., Edwards, Darin K., King, Neil P., Veesler, David
Publicado 2022

Systems biological assessment of human immunity to BNT162b2 mRNA vaccination

por Arunachalam, Prabhu S., Scott, Madeleine K. D., Hagan, Thomas, Li, Chunfeng, Feng, Yupeng, Wimmers, Florian, Grigoryan, Lilit, Trisal, Meera, Edara, Venkata Viswanadh, Lai, Lilin, Chang, Sarah Esther, Feng, Allan, Dhingra, Shaurya, Shah, Mihir, Lee, Allie Skye, Chinthrajah, Sharon, Sindher, Tina, Mallajosyula, Vamsee, Gao, Fei, Sigal, Natalia, Kowli, Sangeeta, Gupta, Sheena, Pellegrini, Kathryn, Tharp, Gregory, Maysel-Auslender, Sofia, Bosinger, Steven, Maecker, Holden T., Boyd, Scott D., Davis, Mark M., Utz, Paul J., Suthar, Mehul S., Khatri, Purvesh, Nadeau, Kari C., Pulendran, Bali
Publicado 2021

Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life

por Wimmers, Florian, Burrell, Allison R., Feng, Yupeng, Zheng, Hong, Arunachalam, Prabhu S., Hu, Mengyun, Spranger, Sara, Nyhoff, Lindsay, Joshi, Devyani, Trisal, Meera, Awasthi, Mayanka, Bellusci, Lorenza, Ashraf, Usama, Kowli, Sangeeta, Konvinse, Katherine C., Yang, Emily, Blanco, Michael, Pellegrini, Kathryn, Tharp, Gregory, Hagan, Thomas, Chinthrajah, R. Sharon, Grifoni, Alba, Sette, Alessandro, Nadeau, Kari C., Haslam, David B., Bosinger, Steven E., Wrammert, Jens, Maecker, Holden T., Utz, Paul J., Wang, Taia T., Khurana, Surender, Khatri, Purvesh, Staat, Mary A., Pulendran, Bali
Publicado 2023

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

por Arunachalam, Prabhu S., Wimmers, Florian, Mok, Chris Ka Pun, Perera, Ranawaka A. P. M., Scott, Madeleine, Hagan, Thomas, Sigal, Natalia, Feng, Yupeng, Bristow, Laurel, Tak-Yin Tsang, Owen, Wagh, Dhananjay, Coller, John, Pellegrini, Kathryn L., Kazmin, Dmitri, Alaaeddine, Ghina, Leung, Wai Shing, Chan, Jacky Man Chun, Chik, Thomas Shiu Hong, Choi, Chris Yau Chung, Huerta, Christopher, Paine McCullough, Michele, Lv, Huibin, Anderson, Evan, Edupuganti, Srilatha, Upadhyay, Amit A., Bosinger, Steve E., Maecker, Holden Terry, Khatri, Purvesh, Rouphael, Nadine, Peiris, Malik, Pulendran, Bali
Publicado 2020