FlaF Is a β-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein

por Banerjee, Ankan, Tsai, Chi-Lin, Chaudhury, Paushali, Tripp, Patrick, Arvai, Andrew S., Ishida, Justin P., Tainer, John A., Albers, Sonja-Verena
Publicado 2015

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

por Wilson, David M., Deacon, Ashley M., Duncton, Matthew A.J., Pellicena, Patricia, Georgiadis, Millie M., Yeh, Andrew P., Arvai, Andrew S., Moiani, Davide, Tainer, John A., Das, Debanu
Publicado 2020

The nucleotide‐dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor

por Chaudhury, Paushali, Neiner, Tomasz, D'Imprima, Edoardo, Banerjee, Ankan, Reindl, Sophia, Ghosh, Abhrajyoti, Arvai, Andrew S., Mills, Deryck J., van der Does, Chris, Tainer, John A., Vonck, Janet, Albers, Sonja‐Verena
Publicado 2015

RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles

por Longo, Michael A., Roy, Sunetra, Chen, Yue, Tomaszowski, Karl-Heinz, Arvai, Andrew S., Pepper, Jordan T., Boisvert, Rebecca A., Kunnimalaiyaan, Selvi, Keshvani, Caezanne, Schild, David, Bacolla, Albino, Williams, Gareth J., Tainer, John A., Schlacher, Katharina
Publicado 2023

An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation

por Nguyen, My T., Moiani, Davide, Ahmed, Zamal, Arvai, Andrew S., Namjoshi, Sarita, Shin, Dave S., Fedorov, Yuriy, Selvik, Edward J., Jones, Darin E., Pink, John, Yan, Yan, Laverty, Daniel J., Nagel, Zachary D., Tainer, John A., Gerson, Stanton L.
Publicado 2021

Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations

por Tsutakawa, Susan E., Sarker, Altaf H., Ng, Clifford, Arvai, Andrew S., Shin, David S., Shih, Brian, Jiang, Shuai, Thwin, Aye C., Tsai, Miaw-Sheue, Willcox, Alexandra, Her, Mai Zong, Trego, Kelly S., Raetz, Alan G., Rosenberg, Daniel, Bacolla, Albino, Hammel, Michal, Griffith, Jack D., Cooper, Priscilla K., Tainer, John A.
Publicado 2020

Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability

por Tsutakawa, Susan E., Thompson, Mark J., Arvai, Andrew S., Neil, Alexander J., Shaw, Steven J., Algasaier, Sana I., Kim, Jane C., Finger, L. David, Jardine, Emma, Gotham, Victoria J.B., Sarker, Altaf H., Her, Mai Z., Rashid, Fahad, Hamdan, Samir M., Mirkin, Sergei M., Grasby, Jane A., Tainer, John A.
Publicado 2017

Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability

por Tsutakawa, Susan E., Thompson, Mark J., Arvai, Andrew S., Neil, Alexander J., Shaw, Steven J., Algasaier, Sana I., Kim, Jane C., Finger, L. David, Jardine, Emma, Gotham, Victoria J. B., Sarker, Altaf H., Her, Mai Z., Rashid, Fahad, Hamdan, Samir M., Mirkin, Sergei M., Grasby, Jane A., Tainer, John A.
Publicado 2017

Alkylated DNA damage flipping bridges base and nucleotide excision repair

por Tubbs, Julie L., Latypov, Vitaly, Kanugula, Sreenivas, Butt, Amna, Melikishvili, Manana, Kraehenbuehl, Rolf, Fleck, Oliver, Marriott, Andrew, Watson, Amanda J., Verbeek, Barbara, McGown, Gail, Thorncroft, Mary, Santibanez-Koref, Mauro F., Millington, Christopher, Arvai, Andrew S., Kroeger, Matthew D., Peterson, Lisa A., Williams, David M., Fried, Michael G., Margison, Geoffrey P., Pegg, Anthony E., Tainer, John A.
Publicado 2009

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

por Garcin, Elsa D., Arvai, Andrew S., Rosenfeld, Robin J., Kroeger, Matt D., Crane, Brian R., Andersson, Gunilla, Andrews, Glen, Hamley, Peter J., Mallinder, Philip R., Nicholls, David J., St-Gallay, Stephen A., Tinker, Alan C., Gensmantel, Nigel P., Mete, Antonio, Cheshire, David R., Connolly, Stephen, Stuehr, Dennis J., Åberg, Anders, Wallace, Alan V., Tainer, John A., Getzoff, Elizabeth D.
Publicado 2008