Prolyl Isomerase Pin1 Regulates Mouse Embryonic Fibroblast Differentiation into Adipose Cells

por Uchida, Takafumi, Furumai, Kengo, Fukuda, Tomokazu, Akiyama, Hirotada, Takezawa, Mika, Asano, Tomoichiro, Fujimori, Fumihiro, Uchida, Chiyoko
Publicado 2012

Roles of peptidyl prolyl isomerase Pin1 in viral propagation

por Kanna, Machi, Nakatsu, Yusuke, Yamamotoya, Takeshi, Encinas, Jeffrey, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Sakaguchi, Takemasa
Publicado 2022

Insulin Receptor Substrate-1 Associates with Small Nucleolar RNA Which Contributes to Ribosome Biogenesis

por Ozoe, Atsufumi, Sone, Meri, Fukushima, Toshiaki, Kataoka, Naoyuki, Chida, Kazuhiro, Asano, Tomoichiro, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Publicado 2014

Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines

por Kanna, Machi, Nakatsu, Yusuke, Yamamotoya, Takeshi, Kushiyama, Akifumi, Fujishiro, Midori, Sakoda, Hideyuki, Ono, Hiraku, Arihiro, Koji, Asano, Tomoichiro
Publicado 2023

High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice

por Shinjo, Takanori, Nakatsu, Yusuke, Iwashita, Misaki, Sano, Tomomi, Sakoda, Hideyuki, Ishihara, Hisamitsu, Kushiyama, Akifumi, Fujishiro, Midori, Nishimura, Fusanori, Asano, Tomoichiro
Publicado 2015

Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet

por Shiwa, Mami, Yoneda, Masayasu, Okubo, Hirofumi, Ohno, Haruya, Kobuke, Kazuhiro, Monzen, Yuko, Kishimoto, Rui, Nakatsu, Yusuke, Asano, Tomoichiro, Kohno, Nobuoki
Publicado 2015

Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages

por Yamazaki, Hiroki, Kushiyama, Akifumi, Sakoda, Hideyuki, Fujishiro, Midori, Yamamotoya, Takeshi, Nakatsu, Yusuke, Kikuchi, Takako, Kaneko, Sunao, Tanaka, Hirotoshi, Asano, Tomoichiro
Publicado 2018

Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications

por Okubo, Hirofumi, Kushiyama, Akifumi, Nakatsu, Yusuke, Yamamotoya, Takeshi, Matsunaga, Yasuka, Fujishiro, Midori, Sakoda, Hideyuki, Ohno, Haruya, Yoneda, Masayasu, Asano, Tomoichiro
Publicado 2018

Adipose-specific C-C motif chemokine ligand (CCL) 19 overexpression drives the mice to both insulin resistance and weight gain

por Hayashi, Masato, Iwashita, Misaki, Nishimura, Yuki, Shinjo, Takanori, Sano, Tomomi, Yamashita, Akiko, Fukuda, Takao, Sanui, Terukazu, Asano, Tomoichiro, Nishimura, Fusanori
Publicado 2021

Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target

por Yamamotoya, Takeshi, Nakatsu, Yusuke, Kanna, Machi, Hasei, Shun, Ohata, Yukino, Encinas, Jeffrey, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Sakaguchi, Takemasa
Publicado 2021

Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice

por Iwashita, Misaki, Nakatsu, Yusuke, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Fukushima, Toshiaki, Kumamoto, Sonoko, Shinjo, Takanori, Kamata, Hideaki, Nishimura, Fusanori, Asano, Tomoichiro
Publicado 2013

A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals

por Uno, Kenji, Yamada, Tetsuya, Ishigaki, Yasushi, Imai, Junta, Hasegawa, Yutaka, Sawada, Shojiro, Kaneko, Keizo, Ono, Hiraku, Asano, Tomoichiro, Oka, Yoshitomo, Katagiri, Hideki
Publicado 2015

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus

por Qiang, Shirong, Nakatsu, Yusuke, Seno, Yasuyuki, Fujishiro, Midori, Sakoda, Hideyuki, Kushiyama, Akifumi, Mori, Keiichi, Matsunaga, Yasuka, Yamamotoya, Takeshi, Kamata, Hideaki, Asano, Tomoichiro
Publicado 2015

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations

por Nakatsu, Yusuke, Matsunaga, Yasuka, Yamamotoya, Takeshi, Ueda, Koji, Inoue, Yuki, Mori, Keiichi, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Kushiyama, Akifumi, Asano, Tomoichiro
Publicado 2016

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis

por Kushiyama, Akifumi, Nakatsu, Yusuke, Matsunaga, Yasuka, Yamamotoya, Takeshi, Mori, Keiichi, Ueda, Koji, Inoue, Yuki, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Asano, Tomoichiro
Publicado 2016

Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure

por Sano, Tomomi, Sanada, Taiki, Sotomaru, Yusuke, Shinjo, Takanori, Iwashita, Misaki, Yamashita, Akiko, Fukuda, Takao, Sanui, Terukazu, Asano, Tomoichiro, Kanematsu, Takashi, Nishimura, Fusanori
Publicado 2019

Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells

por Hasei, Shun, Yamamotoya, Takeshi, Nakatsu, Yusuke, Ohata, Yukino, Itoga, Shota, Nonaka, Yuji, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Kushiyama, Akifumi, Asano, Tomoichiro
Publicado 2021

Reduced SHARPIN and LUBAC Formation May Contribute to CCl(4)- or Acetaminophen-Induced Liver Cirrhosis in Mice

por Yamamotoya, Takeshi, Nakatsu, Yusuke, Matsunaga, Yasuka, Fukushima, Toshiaki, Yamazaki, Hiroki, Kaneko, Sunao, Fujishiro, Midori, Kikuchi, Takako, Kushiyama, Akifumi, Tokunaga, Fuminori, Asano, Tomoichiro, Sakoda, Hideyuki
Publicado 2017

Anti-inflammatory effects of miRNA-146a induced in adipose and periodontal tissues

por Sanada, Taiki, Sano, Tomomi, Sotomaru, Yusuke, Alshargabi, Rehab, Yamawaki, Yosuke, Yamashita, Akiko, Matsunaga, Hiroaki, Iwashita, Misaki, Shinjo, Takanori, Kanematsu, Takashi, Asano, Tomoichiro, Nishimura, Fusanori
Publicado 2020

Pathological Role of Pin1 in the Development of DSS-Induced Colitis

por Matsunaga, Yasuka, Hasei, Shun, Yamamotoya, Takeshi, Honda, Hiroaki, Kushiyama, Akifumi, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Nakatsu, Yusuke
Publicado 2021