Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy

por Jackson, Graham S., Linehan, Jacqueline, Brandner, Sebastian, Asante, Emmanuel A., Wadsworth, Jonathan D. F., Collinge, John
Publicado 2022

The origin of the prion agent of kuru: molecular and biological strain typing

por Wadsworth, Jonathan D.F., Joiner, Susan, Linehan, Jacqueline M., Asante, Emmanuel A., Brandner, Sebastian, Collinge, John
Publicado 2008

Protective Effect of Val(129)-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease

por Fernández-Borges, Natalia, Espinosa, Juan Carlos, Marín-Moreno, Alba, Aguilar-Calvo, Patricia, Asante, Emmanuel A., Kitamoto, Tetsuyuki, Mohri, Shirou, Andréoletti, Olivier, Torres, Juan María
Publicado 2017

Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein

por Joiner, Susan, Asante, Emmanuel A., Linehan, Jacqueline M., Brock, Lara, Brandner, Sebastian, Bellworthy, Susan J., Simmons, Marion M., Hope, James, Collinge, John, Wadsworth, Jonathan D.F.
Publicado 2018

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins

por Asante, Emmanuel A., Gowland, Ian, Grimshaw, Andrew, Linehan, Jacqueline M., Smidak, Michelle, Houghton, Richard, Osiguwa, Olufunmilayo, Tomlinson, Andrew, Joiner, Susan, Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2009

Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein

por Asante, Emmanuel A., Linehan, Jacqueline M., Smidak, Michelle, Tomlinson, Andrew, Grimshaw, Andrew, Jeelani, Asif, Jakubcova, Tatiana, Hamdan, Shyma, Powell, Caroline, Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2013

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

por Sandberg, Malin K., Al-Doujaily, Huda, Sigurdson, Christina J., Glatzel, Markus, O'Malley, Catherine, Powell, Caroline, Asante, Emmanuel A., Linehan, Jacqueline M., Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2010

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS

por Asante, Emmanuel A., Grimshaw, Andrew, Smidak, Michelle, Jakubcova, Tatiana, Tomlinson, Andrew, Jeelani, Asif, Hamdan, Shyma, Powell, Caroline, Joiner, Susan, Linehan, Jacqueline M., Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2015

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

por Asante, Emmanuel A., Linehan, Jacqueline M., Tomlinson, Andrew, Jakubcova, Tatiana, Hamdan, Shyma, Grimshaw, Andrew, Smidak, Michelle, Jeelani, Asif, Nihat, Akin, Mead, Simon, Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2020

Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein

por Wadsworth, Jonathan D.F., Joiner, Susan, Linehan, Jacqueline M., Balkema-Buschmann, Anne, Spiropoulos, John, Simmons, Marion M., Griffiths, Peter C., Groschup, Martin H., Hope, James, Brandner, Sebastian, Asante, Emmanuel A., Collinge, John
Publicado 2013

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology

por Clayton, Emma L., Mizielinska, Sarah, Edgar, James R., Nielsen, Troels Tolstrup, Marshall, Sarah, Norona, Frances E., Robbins, Miranda, Damirji, Hana, Holm, Ida E., Johannsen, Peter, Nielsen, Jørgen E., Asante, Emmanuel A., Collinge, John, Isaacs, Adrian M.
Publicado 2015

A naturally occurring variant of the human prion protein completely prevents prion disease

por Asante, Emmanuel A., Smidak, Michelle, Grimshaw, Andrew, Houghton, Richard, Tomlinson, Andrew, Jeelani, Asif, Jakubcova, Tatiana, Hamdan, Shyma, Richard-Londt, Angela, Linehan, Jacqueline M., Brandner, Sebastian, Alpers, Michael, Whitfield, Jerome, Mead, Simon, Wadsworth, Jonathan D.F., Collinge, John
Publicado 2015

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

por Freir, Darragh B., Nicoll, Andrew J., Klyubin, Igor, Panico, Silvia, Mc Donald, Jessica M., Risse, Emmanuel, Asante, Emmanuel A., Farrow, Mark A., Sessions, Richard B., Saibil, Helen R., Clarke, Anthony R., Rowan, Michael J., Walsh, Dominic M., Collinge, John
Publicado 2011

Humanized Transgenic Mice Are Resistant to Chronic Wasting Disease Prions From Norwegian Reindeer and Moose( )

por Wadsworth, Jonathan D F, Joiner, Susan, Linehan, Jacqueline M, Jack, Kezia, Al-Doujaily, Huda, Costa, Helena, Ingold, Thea, Taema, Maged, Zhang, Fuquan, Sandberg, Malin K, Brandner, Sebastian, Tran, Linh, Vikøren, Turid, Våge, Jørn, Madslien, Knut, Ytrehus, Bjørnar, Benestad, Sylvie L, Asante, Emmanuel A, Collinge, John
Publicado 2021