huva: A human variation analysis framework to predict gene perturbation from population-scale multi-omics data

por Aschenbrenner, Anna C., Bonaguro, Lorenzo
Publicado 2023

Neue Krankheiten mit Bluttranskriptomik entschlüsseln

por Ulas, Thomas, Aschenbrenner, Anna C.
Publicado 2021

COVID-19 and the human innate immune system

por Schultze, Joachim L., Aschenbrenner, Anna C.
Publicado 2021

Modeling population heterogeneity from microbial communities to immune response in cells

por Pecht, Tal, Aschenbrenner, Anna C., Ulas, Thomas, Succurro, Antonella
Publicado 2019

Classes of non-conventional tetraspanins defined by alternative splicing

por Hochheimer, Nikolas, Sies, Ricarda, Aschenbrenner, Anna C., Schneider, Dirk, Lang, Thorsten
Publicado 2019

Dysregulated Functions of Lung Macrophage Populations in COPD

por Kapellos, Theodore S., Bassler, Kevin, Aschenbrenner, Anna C., Fujii, Wataru, Schultze, Joachim L.
Publicado 2018

Neutrophils in COVID-19

por Reusch, Nico, De Domenico, Elena, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Baßler, Kevin, Schultze, Joachim L., Aschenbrenner, Anna C.
Publicado 2021

Differential Gene Expression in Circulating CD14(+) Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis

por Liepelt, Anke, Hohlstein, Philipp, Gussen, Hendrik, Xue, Jia, Aschenbrenner, Anna C., Ulas, Thomas, Buendgens, Lukas, Warzecha, Klaudia T., Bartneck, Matthias, Luedde, Tom, Trautwein, Christian, Schultze, Joachim L., Koch, Alexander, Tacke, Frank
Publicado 2020

Alveolar macrophage transcriptomic profiling in COPD shows major lipid metabolism changes

por Fujii, Wataru, Kapellos, Theodore S., Baßler, Kevin, Händler, Kristian, Holsten, Lisa, Knoll, Rainer, Warnat-Herresthal, Stefanie, Oestreich, Marie, Hinkley, Emily R., Hasenauer, Jan, Pizarro, Carmen, Thiele, Christoph, Aschenbrenner, Anna C., Ulas, Thomas, Skowasch, Dirk, Schultze, Joachim L.
Publicado 2021

Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state

por Carraro, Caterina, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Horne, Arik, Oestreich, Marie, Warnat-Herresthal, Stefanie, Helbing, Tim, De Franco, Michele, Haendler, Kristian, Mukherjee, Sach, Ulas, Thomas, Gandin, Valentina, Goettlich, Richard, Aschenbrenner, Anna C, Schultze, Joachim L, Gatto, Barbara
Publicado 2022

Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs

por Langkabel, Jan, Horne, Arik, Bonaguro, Lorenzo, Holsten, Lisa, Hesse, Tatiana, Knaus, Alexej, Riedel, Yannick, Becker, Matthias, Händler, Kristian, Elmzzahi, Tarek, Bassler, Kevin, Reusch, Nico, Yeghiazarian, Leon Harootoonovtch, Pecht, Tal, Saglam, Adem, Ulas, Thomas, Aschenbrenner, Anna C., Kaiser, Franziska, Kubaczka, Caroline, Schultze, Joachim L., Schorle, Hubert
Publicado 2021

Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19

por Kooistra, Emma J., Dahm, Kilian, van Herwaarden, Antonius E., Gerretsen, Jelle, Nuesch Germano, Melanie, Mauer, Karoline, Smeets, Ruben L., van der Velde, Sjef, van den Berg, Maarten J. W., van der Hoeven, Johannes G., Aschenbrenner, Anna C., Schultze, Joachim L., Ulas, Thomas, Kox, Matthijs, Pickkers, Peter
Publicado 2023

Human variation in population-wide gene expression data predicts gene perturbation phenotype

por Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Carraro, Caterina, Sun, Laura L., Reiz, Benedikt, Gemünd, Ioanna, Saglam, Adem, Rahmouni, Souad, Georges, Michel, Arts, Peer, Hoischen, Alexander, Joosten, Leo A.B., van de Veerdonk, Frank L., Netea, Mihai G., Händler, Kristian, Mukherjee, Sach, Ulas, Thomas, Schultze, Joachim L., Aschenbrenner, Anna C.
Publicado 2022

Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq

por Carraro, Caterina, Bonaguro, Lorenzo, Srinivasa, Rachana, van Uelft, Martina, Isakzai, Victoria, Schulte-Schrepping, Jonas, Gambhir, Prerna, Elmzzahi, Tarek, Montgomery, Jessica V., Hayer, Hannah, Li, Yuanfang, Theis, Heidi, Kraut, Michael, Mahbubani, Krishnaa T., Aschenbrenner, Anna C., König, Ireen, Fava, Eugenio, Fried, Hans-Ulrich, De Domenico, Elena, Beyer, Marc, Saglam, Adem, Schultze, Joachim L.
Publicado 2023

NCX1 represents an ionic Na(+) sensing mechanism in macrophages

por Neubert, Patrick, Homann, Arne, Wendelborn, David, Bär, Anna-Lorena, Krampert, Luka, Trum, Maximilian, Schröder, Agnes, Ebner, Stefan, Weichselbaum, Andrea, Schatz, Valentin, Linz, Peter, Veelken, Roland, Schulte-Schrepping, Jonas, Aschenbrenner, Anna C., Quast, Thomas, Kurts, Christian, Geisberger, Sabrina, Kunzelmann, Karl, Hammer, Karin, Binger, Katrina J., Titze, Jens, Müller, Dominik N., Kolanus, Waldemar, Schultze, Joachim L., Wagner, Stefan, Jantsch, Jonathan
Publicado 2020

Mature neutrophils and a NF-κB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19

por Frishberg, Amit, Kooistra, Emma, Nuesch-Germano, Melanie, Pecht, Tal, Milman, Neta, Reusch, Nico, Warnat-Herresthal, Stefanie, Bruse, Niklas, Händler, Kristian, Theis, Heidi, Kraut, Michael, van Rijssen, Esther, van Cranenbroek, Bram, Koenen, Hans JPM., Heesakkers, Hidde, van den Boogaard, Mark, Zegers, Marieke, Pickkers, Peter, Becker, Matthias, Aschenbrenner, Anna C., Ulas, Thomas, Theis, Fabian J., Shen-Orr, Shai S., Schultze, Joachim L., Kox, Matthijs
Publicado 2022

Fighting Post-COVID and ME/CFS – development of curative therapies

por Scheibenbogen, Carmen, Bellmann-Strobl, Judith Theresia, Heindrich, Cornelia, Wittke, Kirsten, Stein, Elisa, Franke, Christiana, Prüss, Harald, Preßler, Hannah, Machule, Marie-Luise, Audebert, Heinrich, Finke, Carsten, Zimmermann, Hanna Gwendolyn, Sawitzki, Birgit, Meisel, Christian, Toelle, Markus, Krueger, Anne, Aschenbrenner, Anna C., Schultze, Joachim L., Beyer, Marc D., Ralser, Markus, Mülleder, Michael, Sander, Leif Erik, Konietschke, Frank, Paul, Friedemann, Stojanov, Silvia, Bruckert, Lisa, Hedderich, Dennis M., Knolle, Franziska, Riemekasten, Gabriela, Vehreschild, Maria J. G. T., Cornely, Oliver A., Behrends, Uta, Burock, Susen
Publicado 2023

Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2

por Sander, Jil, Schmidt, Susanne V., Cirovic, Branko, McGovern, Naomi, Papantonopoulou, Olympia, Hardt, Anna-Lena, Aschenbrenner, Anna C., Kreer, Christoph, Quast, Thomas, Xu, Alexander M., Schmidleithner, Lisa M., Theis, Heidi, Thi Huong, Lan Do, Sumatoh, Hermi Rizal Bin, Lauterbach, Mario A.R., Schulte-Schrepping, Jonas, Günther, Patrick, Xue, Jia, Baßler, Kevin, Ulas, Thomas, Klee, Kathrin, Katzmarski, Natalie, Herresthal, Stefanie, Krebs, Wolfgang, Martin, Bianca, Latz, Eicke, Händler, Kristian, Kraut, Michael, Kolanus, Waldemar, Beyer, Marc, Falk, Christine S., Wiegmann, Bettina, Burgdorf, Sven, Melosh, Nicholas A., Newell, Evan W., Ginhoux, Florent, Schlitzer, Andreas, Schultze, Joachim L.
Publicado 2017

Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation

por Baßler, Kevin, Fujii, Wataru, Kapellos, Theodore S., Dudkin, Erika, Reusch, Nico, Horne, Ari, Reiz, Benedikt, Luecken, Malte D., Osei-Sarpong, Collins, Warnat-Herresthal, Stefanie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Wagner, Allon, Günther, Patrick, Pizarro, Carmen, Schreiber, Tina, Knoll, Rainer, Holsten, Lisa, Kröger, Charlotte, De Domenico, Elena, Becker, Matthias, Händler, Kristian, Wohnhaas, Christian T., Baumgartner, Florian, Köhler, Meike, Theis, Heidi, Kraut, Michael, Wadsworth, Marc H., Hughes, Travis K., Ferreira, Humberto J., Hinkley, Emily, Kaltheuner, Ines H., Geyer, Matthias, Thiele, Christoph, Shalek, Alex K., Feißt, Andreas, Thomas, Daniel, Dickten, Henning, Beyer, Marc, Baum, Patrick, Yosef, Nir, Aschenbrenner, Anna C., Ulas, Thomas, Hasenauer, Jan, Theis, Fabian J., Skowasch, Dirk, Schultze, Joachim L.
Publicado 2022

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

por Krämer, Benjamin, Knoll, Rainer, Bonaguro, Lorenzo, ToVinh, Michael, Raabe, Jan, Astaburuaga-García, Rosario, Schulte-Schrepping, Jonas, Kaiser, Kim Melanie, Rieke, Gereon J., Bischoff, Jenny, Monin, Malte B., Hoffmeister, Christoph, Schlabe, Stefan, De Domenico, Elena, Reusch, Nico, Händler, Kristian, Reynolds, Gary, Blüthgen, Nils, Hack, Gudrun, Finnemann, Claudia, Nischalke, Hans D., Strassburg, Christian P., Stephenson, Emily, Su, Yapeng, Gardner, Louis, Yuan, Dan, Chen, Daniel, Goldman, Jason, Rosenstiel, Philipp, Schmidt, Susanne V., Latz, Eicke, Hrusovsky, Kevin, Ball, Andrew J., Johnson, Joe M., Koenig, Paul-Albert, Schmidt, Florian I., Haniffa, Muzlifah, Heath, James R., Kümmerer, Beate M., Keitel, Verena, Jensen, Björn, Stubbemann, Paula, Kurth, Florian, Sander, Leif E., Sawitzki, Birgit, Aschenbrenner, Anna C., Schultze, Joachim L., Nattermann, Jacob
Publicado 2021