Prions, prionoids and pathogenic proteins in Alzheimer disease

por Ashe, Karen H., Aguzzi, Adriano
Publicado 2013

The molecular implications of a caspase-2-mediated site-specific tau cleavage in tauopathies

por Liu, Peng, Ashe, Karen H.
Publicado 2021

β-Amyloid oligomers in aging and Alzheimer’s disease

por Zahs, Kathleen R., Ashe, Karen H.
Publicado 2013

Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau

por Orr, Miranda E., Pitstick, Rose, Canine, Brenda, Ashe, Karen H., Carlson, George A.
Publicado 2012

A Cautionary Tale: Endogenous Biotinylated Proteins and Exogenously-Introduced Protein A Cause Antibody-Independent Artefacts in Western Blot Studies of Brain-Derived Proteins

por Grant, Marianne K. O., Shapiro, Samantha L., Ashe, Karen H., Liu, Peng, Zahs, Kathleen R.
Publicado 2019

Characterization of a Novel Mouse Model of Alzheimer’s Disease—Amyloid Pathology and Unique β-Amyloid Oligomer Profile

por Liu, Peng, Paulson, Jennifer B., Forster, Colleen L., Shapiro, Samantha L., Ashe, Karen H., Zahs, Kathleen R.
Publicado 2015

Factors other than hTau overexpression that contribute to tauopathy-like phenotype in rTg4510 mice

por Gamache, Julia, Benzow, Kellie, Forster, Colleen, Kemper, Lisa, Hlynialuk, Chris, Furrow, Eva, Ashe, Karen H., Koob, Michael D.
Publicado 2019

A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

por Smith, Benjamin R., Nelson, Kathryn M., Kemper, Lisa J., Leinonen-Wright, Kailee, Petersen, Ashley, Keene, C. Dirk, Ashe, Karen H.
Publicado 2019

Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments

por Grant, Marianne K. O., Handoko, Maureen, Rozga, Malgorzata, Brinkmalm, Gunnar, Portelius, Erik, Blennow, Kaj, Ashe, Karen H., Zahs, Kathleen R., Liu, Peng
Publicado 2019

A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington’s disease patients

por Liu, Peng, Smith, Benjamin R., Huang, Eric S., Mahesh, Abhishek, Vonsattel, Jean Paul G., Petersen, Ashley J., Gomez-Pastor, Rocio, Ashe, Karen H.
Publicado 2019

Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque transg...

por Qi, Yingjie, Klyubin, Igor, Harney, Sarah C, Hu, NengWei, Cullen, William K, Grant, Marianne K, Steffen, Julia, Wilson, Edward N, Do Carmo, Sonia, Remy, Stefan, Fuhrmann, Martin, Ashe, Karen H, Cuello, A Claudio, Rowan, Michael J
Publicado 2014

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

por Liu, Peng, Smith, Benjamin R., Montonye, Michelle L., Kemper, Lisa J., Leinonen-Wright, Kailee, Nelson, Kathryn M., Higgins, LeeAnn, Guerrero, Candace R., Markowski, Todd W., Zhao, Xiaohui, Petersen, Ashley J., Knopman, David S., Petersen, Ronald C., Ashe, Karen H.
Publicado 2020

Author Correction: A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

por Liu, Peng, Smith, Benjamin R., Montonye, Michelle L., Kemper, Lisa J., Leinonen-Wright, Kailee, Nelson, Kathryn M., Higgins, LeeAnn, Guerrero, Candace R., Markowski, Todd W., Zhao, Xiaohui, Petersen, Ashley J., Knopman, David S., Petersen, Ronald C., Ashe, Karen H.
Publicado 2020

Accumulation of pTau231 at the Postsynaptic Density in Early Alzheimer’s Disease

por Lilek, Jaclyn, Ajroud, Kaouther, Feldman, Alexander Z., Krishnamachari, Sesha, Ghourchian, Shadi, Gefen, Tamar, Spencer, Callen L., Kawles, Allegra, Mao, Qinwen, Tranovich, Jessica F., Jack, Clifford R., Mesulam, M-Marsel, Reichard, R. Ross, Zhang, Hui, Murray, Melissa E., Knopman, David, Dickson, Dennis W., Petersen, Ronald C., Smith, Benjamin, Ashe, Karen H., Mielke, Michelle M., Nelson, Kathryn M., Flanagan, Margaret E.
Publicado 2023