Insulin-signalling dysregulation and inflammation is programmed trans-generationally in a female rat model of poor maternal nutrition

por Tarry-Adkins, Jane L., Aiken, Catherine E., Ashmore, Thomas J., Ozanne, Susan E.
Publicado 2018

Maternal Metformin Intervention during Obese Glucose-Intolerant Pregnancy Affects Adiposity in Young Adult Mouse Offspring in a Sex-Specific Manner

por Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Aiken, Catherine E., Fernandez-Twinn, Denise S., Ozanne, Susan E.
Publicado 2021

A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats

por Tarry-Adkins, Jane L., Aiken, Catherine E., Ashmore, Thomas J., Fernandez-Twinn, Denise S., Chen, Jian-Hua, Ozanne, Susan E.
Publicado 2019

Maternal but not fetoplacental health can be improved by metformin in a murine diet-induced model of maternal obesity and glucose intolerance

por Hufnagel, Antonia, Fernandez-Twinn, Denise S, Blackmore, Heather L, Ashmore, Thomas J, Heaton, Robert A, Jenkins, Benjamin, Koulman, Albert, Hargreaves, Iain P, Aiken, Catherine E, Ozanne, Susan E
Publicado 2022

Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring

por Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Pantaleão, Lucas C., Pellegrini Pisani, Luciana, Dearden, Laura, Tadross, John A., Aiken, Catherine E., Fernandez-Twinn, Denise S., Ozanne, Susan E.
Publicado 2022

Chronic fetal hypoxia disrupts the peri‐conceptual environment in next‐generation adult female rats

por Aiken, Catherine E., Tarry‐Adkins, Jane L., Spiroski, Ana‐Mishel, Nuzzo, Anna M., Ashmore, Thomas J., Rolfo, Alessandro, Sutherland, Megan J., Camm, Emily J., Giussani, Dino A., Ozanne, Susan E.
Publicado 2019

Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats

por Aiken, Catherine E., Tarry-Adkins, Jane L., Spiroski, Ana-Mishel, Nuzzo, Anna M., Ashmore, Thomas J., Rolfo, Alessandro, Sutherland, Megan J., Camm, Emily J., Giussani, Dino A., Ozanne, Susan E.
Publicado 2019

Impact of maternal obesity on placental transcriptome and morphology associated with fetal growth restriction in mice

por de Barros Mucci, Daniela, Kusinski, Laura C., Wilsmore, Phoebe, Loche, Elena, Pantaleão, Lucas C., Ashmore, Thomas J., Blackmore, Heather L., Fernandez-Twinn, Denise S., Carmo, Maria das Graças T. do, Ozanne, Susan E.
Publicado 2020

Mitochondria antioxidant protection against cardiovascular dysfunction programmed by early-onset gestational hypoxia

por Spiroski, Ana-Mishel, Niu, Youguo, Nicholas, Lisa M., Austin-Williams, Shani, Camm, Emily J., Sutherland, Megan R., Ashmore, Thomas J., Skeffington, Katie. L., Logan, Angela, Ozanne, Susan E., Murphy, Michael P., Giussani, Dino A.
Publicado 2021

Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet

por Loche, Elena, Blackmore, Heather L, Carpenter, Asha A, Beeson, Jessica H, Pinnock, Adele, Ashmore, Thomas J, Aiken, Catherine E, de Almeida-Faria, Juliana, Schoonejans, Josca M, Giussani, Dino A, Fernandez-Twinn, Denise S, Ozanne, Susan E
Publicado 2018

Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy

por Niu, Youguo, Kane, Andrew D., Lusby, Ciara M., Allison, Beth J., Chua, Yi Yi, Kaandorp, Joepe J., Nevin-Dolan, Rhiannon, Ashmore, Thomas J., Blackmore, Heather L., Derks, Jan B., Ozanne, Susan E., Giussani, Dino A.
Publicado 2018

Maternal obesity during pregnancy leads to adipose tissue ER stress in mice via miR-126-mediated reduction in Lunapark

por de Almeida-Faria, Juliana, Duque-Guimarães, Daniella E., Ong, Thomas P., Pantaleão, Lucas C., Carpenter, Asha A., Loche, Elena, Kusinski, Laura C., Ashmore, Thomas J., Antrobus, Robin, Bushell, Martin, Fernandez-Twinn, Denise S., Ozanne, Susan E.
Publicado 2021

Effects of maternal diet-induced obesity on metabolic disorders and age-associated miRNA expression in the liver of male mouse offspring

por Mennitti, Laís Vales, Carpenter, Asha A. M., Loche, Elena, Pantaleão, Lucas C., Fernandez-Twinn, Denise S., Schoonejans, Josca M., Blackmore, Heather L., Ashmore, Thomas J., Pisani, Luciana Pellegrini, Tadross, John A., Hargreaves, Iain, Ozanne, Susan E.
Publicado 2021

Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model

por Nuzzo, Anna M., Camm, Emily J., Sferruzzi-Perri, Amanda N., Ashmore, Thomas J., Yung, Hong-wa, Cindrova-Davies, Tereza, Spiroski, Ana-Mishel, Sutherland, Megan R., Logan, Angela, Austin-Williams, Shani, Burton, Graham J., Rolfo, Alessandro, Todros, Tullia, Murphy, Michael P., Giussani, Dino A.
Publicado 2018

Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system

por Teulings, Noor E. W. D., Garrud, Tessa A. C., Niu, Youguo, Skeffington, Katie L., Beck, Christian, Itani, Nozomi, Conlon, Fiona G., Botting, Kimberley J., Nicholas, Lisa M., Ashmore, Thomas J., Blackmore, Heather L., Tong, Wen, Camm, Emily J., Derks, Jan B., Logan, Angela, Murphy, Michael P., Ozanne, Susan E., Giussani, Dino A.
Publicado 2020