Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis

por Yao, Yimin, Findlay, Alison, Stolp, Jessica, Rayner, Benjamin, Ask, Kjetil, Jarolimek, Wolfgang
Publicado 2022

IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity

por El-Sayes, Nader, Walsh, Scott, Vito, Alyssa, Reihani, Amir, Ask, Kjetil, Wan, Yonghong, Mossman, Karen
Publicado 2022

The physician factor and anatomical site in 8846 consecutive mediastinal lymph node aspirations in a cross-sectional study

por Bonert, Michael, Zafar, Uzma, Ramadan, Soha, Finley, Christian, Cutz, Jean-Claude, Foster, Gary, Ask, Kjetil, Naqvi, Asghar
Publicado 2023

Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis

por Ayaub, Ehab A., Dubey, Anisha, Imani, Jewel, Botelho, Fernando, Kolb, Martin R. J., Richards, Carl D., Ask, Kjetil
Publicado 2017

Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease

por Soomro, Asfia, Trink, Jackie, O’Neil, Kian, Li, Renzhong, Naiel, Safaa, Gao, Bo, Ask, Kjetil, Krepinsky, Joan C.
Publicado 2021

4-Phenylbutyrate Inhibits Tunicamycin-Induced Acute Kidney Injury via CHOP/GADD153 Repression

por Carlisle, Rachel E., Brimble, Elise, Werner, Kaitlyn E., Cruz, Gaile L., Ask, Kjetil, Ingram, Alistair J., Dickhout, Jeffrey G.
Publicado 2014

Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD

por Mohammed-Ali, Zahraa, Cruz, Gaile L., Lu, Chao, Carlisle, Rachel E., Werner, Kaitlyn E., Ask, Kjetil, Dickhout, Jeffrey G.
Publicado 2015

Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria

por Mohammed-Ali, Zahraa, Lu, Chao, Marway, Mandeep K., Carlisle, Rachel E., Ask, Kjetil, Lukic, Dusan, Krepinsky, Joan C., Dickhout, Jeffrey G.
Publicado 2017

Oncolytic BHV-1 Is Sufficient to Induce Immunogenic Cell Death and Synergizes with Low-Dose Chemotherapy to Dampen Immunosuppressive T Regulatory Cells

por Davola, Maria Eugenia, Cormier, Olga, Vito, Alyssa, El-Sayes, Nader, Collins, Susan, Salem, Omar, Revill, Spencer, Ask, Kjetil, Wan, Yonghong, Mossman, Karen
Publicado 2023

Comparison between conventional and "clinical" assessment of experimental lung fibrosis

por Ask, Kjetil, Labiris, Renee, Farkas, Laszlo, Moeller, Antje, Froese, Aaron, Farncombe, Troy, McClelland, Grant B, Inman, Mark, Gauldie, Jack, Kolb, Martin RJ
Publicado 2008

Galectin-3 levels are elevated following nintedanib treatment

por Shochet, Gali Epstein, Pomerantz, Alon, Shitrit, David, Bardenstein-Wald, Becky, Ask, Kjetil, Surber, Mark, Rabinowicz, Noa, Levy, Yair, Benchetrit, Sydney, Edelstein, Evgeny, Zitman-Gal, Tali
Publicado 2020

Circulating fibrocytes are not disease-specific prognosticators in idiopathic pulmonary fibrosis

por Stewart, Iain D., Nanji, Henry, Figueredo, Grazziela, Fahy, William A., Maher, Toby M., Ask, Antje J., Maharaj, Shyam, Ask, Kjetil, Kolb, Martin, Jenkins, Gisli R.
Publicado 2021

Advanced detection strategies for cardiotropic virus infection in a cohort study of heart failure patients

por Hanson, Paul J., Liu-Fei, Felicia, Minato, Taylor A., Hossain, Al Rohet, Rai, Harpreet, Chen, Victoria A., Ng, Coco, Ask, Kjetil, Hirota, Jeremy A., McManus, Bruce M.
Publicado 2021

Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth

por Lhoták, Šárka, Gyulay, Gabriel, Cutz, Jean‐Claude, Al‐Hashimi, Ali, Trigatti, Bernardo L., Richards, Carl D., Igdoura, Suleiman A., Steinberg, Gregory R., Bramson, Jonathan, Ask, Kjetil, Austin, Richard C.
Publicado 2016

ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells

por Cao, Quynh T., Aguiar, Jennifer A., Tremblay, Benjamin J-M., Abbas, Nadin, Tiessen, Nicholas, Revill, Spencer, Makhdami, Nima, Ayoub, Anmar, Cox, Gerard, Ask, Kjetil, Doxey, Andrew C., Hirota, Jeremy A.
Publicado 2020

Potentiation of long-acting β(2)-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP

por Kim, Yechan, Hou, Vincent, Huff, Ryan D., Aguiar, Jennifer A., Revill, Spencer, Tiessen, Nicholas, Cao, Quynh, Miller, Matthew S., Inman, Mark D., Ask, Kjetil, Doxey, Andrew C., Hirota, Jeremy A.
Publicado 2021

Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1

por Rodt, Thomas, von Falck, Christian, Dettmer, Sabine, Halter, Roman, Maus, Regina, Ask, Kjetil, Kolb, Martin, Gauldie, Jack, Länger, Florian, Hoy, Ludwig, Welte, Tobias, Galanski, Michael, Maus, Ulrich A, Borlak, Jürgen
Publicado 2010

Cannabis smoke suppresses antiviral immune responses to influenza A in mice

por Milad, Nadia, Fantauzzi, Matthew F., McGrath, Joshua J.C., Cass, Steven P., Thayaparan, Danya, Wang, Peiyao, Afkhami, Sam, Aguiar, Jennifer A., Ask, Kjetil, Doxey, Andrew C., Stampfli, Martin R., Hirota, Jeremy A.
Publicado 2023

Expression of endocannabinoid system components in human airway epithelial cells: impact of sex and chronic respiratory disease status

por Fantauzzi, Matthew F., Aguiar, Jennifer A., Tremblay, Benjamin J.-M., Mansfield, Michael J., Yanagihara, Toyoshi, Chandiramohan, Abiram, Revill, Spencer, Ryu, Min Hyung, Carlsten, Chris, Ask, Kjetil, Stämpfli, Martin, Doxey, Andrew C., Hirota, Jeremy A.
Publicado 2020

A Robust Protocol for Decellularized Human Lung Bioink Generation Amenable to 2D and 3D Lung Cell Culture

por Dabaghi, Mohammadhossein, Saraei, Neda, Carpio, Mabel Barreiro, Nanduri, Vibudha, Ungureanu, Julia, Babi, Mouhanad, Chandiramohan, Abiram, Noble, Alexander, Revill, Spencer D., Zhang, Boyang, Ask, Kjetil, Kolb, Martin, Shargall, Yaron, Moran-Mirabal, Jose, Hirota, Jeremy Alexander
Publicado 2021