Toward lentiviral vectors for antiangiogenic ocular gene therapy

por Askou, Anne Louise, Jakobsen, Thomas Stax, Corydon, Thomas J.
Publicado 2023

Local Adenoviral Delivery of Vascular Endothelial Growth Factor C Induces Lymphangiogenesis in the Conjunctiva in Rabbits

por Rasic, Dusan, Wirenfeldt, Martin, Askou, Anne Louise, Corydon, Thomas J., Telinius, Niklas
Publicado 2023

Subretinal Saline Protects the Neuroretina From Thermic Damage During Laser Induction of Experimental Choroidal Neovascularization in Pigs

por Hansen, Silja, Askou, Anne Louise, la Cour, Morten, Corydon, Thomas J., Bek, Toke
Publicado 2021

Associations between the Complement System and Choroidal Neovascularization in Wet Age-Related Macular Degeneration

por Jensen, Emilie Grarup, Jakobsen, Thomas Stax, Thiel, Steffen, Askou, Anne Louise, Corydon, Thomas J.
Publicado 2020

Targeted Knockout of the Vegfa Gene in the Retina by Subretinal Injection of RNP Complexes Containing Cas9 Protein and Modified sgRNAs

por Holmgaard, Andreas Braae, Askou, Anne Louise, Jensen, Emilie Grarup, Alsing, Sidsel, Bak, Rasmus O., Mikkelsen, Jacob Giehm, Corydon, Thomas J.
Publicado 2021

Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina

por Jakobsen, Thomas Stax, Østergaard, Jakob Appel, Kjolby, Mads, Birch, Elisa Lund, Bek, Toke, Nykjaer, Anders, Corydon, Thomas J., Askou, Anne Louise
Publicado 2023

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

por Askou, Anne Louise, Alsing, Sidsel, Benckendorff, Josephine N.E., Holmgaard, Andreas, Mikkelsen, Jacob Giehm, Aagaard, Lars, Bek, Toke, Corydon, Thomas J.
Publicado 2019

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells

por Holmgaard, Andreas, Askou, Anne Louise, Benckendorff, Josephine Natalia Esther, Thomsen, Emil Aagaard, Cai, Yujia, Bek, Toke, Mikkelsen, Jacob Giehm, Corydon, Thomas J.
Publicado 2017

Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

por Askou, Anne Louise, Aagaard, Lars, Kostic, Corinne, Arsenijevic, Yvan, Hollensen, Anne Kruse, Bek, Toke, Jensen, Thomas Gryesten, Mikkelsen, Jacob Giehm, Corydon, Thomas Juhl
Publicado 2015

25 years of maturation: A systematic review of RNAi in the clinic

por Corydon, Ida Juhl, Fabian-Jessing, Bjørn Kristensen, Jakobsen, Thomas Stax, Jørgensen, Asbjørn Cortnum, Jensen, Emilie Grarup, Askou, Anne Louise, Aagaard, Lars, Corydon, Thomas Juhl
Publicado 2023

VEGFA-targeting miR-agshRNAs combine efficacy with specificity and safety for retinal gene therapy

por Alsing, Sidsel, Doktor, Thomas Koed, Askou, Anne Louise, Jensen, Emilie Grarup, Ahmadov, Ulvi, Kristensen, Lasse Sommer, Andresen, Brage Storstein, Aagaard, Lars, Corydon, Thomas J.
Publicado 2022

Animal Models of Choroidal Neovascularization: A Systematic Review

por Fabian-Jessing, Bjørn K., Jakobsen, Thomas Stax, Jensen, Emilie Grarup, Alsing, Sidsel, Hansen, Silja, Aagaard, Lars, Askou, Anne Louise, Bek, Toke, Corydon, Thomas J.
Publicado 2022

Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein

por Dalsgaard, Trine, Cecchi, Claudia R., Askou, Anne Louise, Bak, Rasmus O., Andersen, Pernille O., Hougaard, David, Jensen, Thomas G., Dagnæs-Hansen, Frederik, Mikkelsen, Jacob Giehm, Corydon, Thomas J., Aagaard, Lars
Publicado 2018

Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of CRISPR/Cas ribonucleoprotein complexes supporting base editing, prime editing and in vivo gene modification

por Haldrup, Jakob, Andersen, Sofie, Labial, Alexander Rafael LaVilla, Wolff, Jonas Holst, Frandsen, Frederik Plum, Skov, Thomas Wisbech, Rovsing, Anne Bruun, Nielsen, Ian, Jakobsen, Thomas Stax, Askou, Anne Louise, Thomsen, Martin K, Corydon, Thomas J, Thomsen, Emil Aagaard, Mikkelsen, Jacob Giehm
Publicado 2023