Flavor of Iron at EHA2023: Novel Regulatory Mechanisms and Therapeutic Options for the Correction of Anemia

por Vinchi, Francesca, Asperti, Michela, Marques, Oriana, Nai, Antonella, Silvestri, Laura
Publicado 2023

Hepcidin antagonists for potential treatments of disorders with hepcidin excess

por Poli, Maura, Asperti, Michela, Ruzzenenti, Paola, Regoni, Maria, Arosio, Paolo
Publicado 2014

Non-Anticoagulant Heparins Are Hepcidin Antagonists for the Treatment of Anemia

por Poli, Maura, Asperti, Michela, Ruzzenenti, Paola, Naggi, Annamaria, Arosio, Paolo
Publicado 2017

S283: THE NON-ANTICOAGULANT HEPARINOID COMPOUND, SEVUPARIN, STRONGLY REDUCES HEPCIDIN EXPRESSION IN CELLS, IN MICE AND IN HEALTHY VOLUNTEERS

por Asperti, Michela, Denardo, Andrea, Gryzik, Magdalena, Persson, Kristina E. M., Westerberg, Göran, Öhd, John, Poli, Maura
Publicado 2023

High Sulfation and a High Molecular Weight Are Important for Anti-hepcidin Activity of Heparin

por Asperti, Michela, Naggi, Annamaria, Esposito, Emiliano, Ruzzenenti, Paola, Di Somma, Margherita, Gryzik, Magdalena, Arosio, Paolo, Poli, Maura
Publicado 2016

The modulation of iron metabolism affects the Rhabdomyosarcoma tumor growth in vitro and in vivo

por Asperti, Michela, Cantamessa, Luca, Gryzik, Magdalena, Bugatti, Mattia, Codenotti, Silvia, Denardo, Andrea, Vermi, William, Fanzani, Alessandro, Poli, Maura
Publicado 2023

Heparanase Overexpression Reduces Hepcidin Expression, Affects Iron Homeostasis and Alters the Response to Inflammation

por Asperti, Michela, Stuemler, Tanja, Poli, Maura, Gryzik, Magdalena, Lifshitz, Lena, Meyron-Holtz, Esther G., Vlodavsky, Israel, Arosio, Paolo
Publicado 2016

Biochemical, Biophysical and Functional Characterization of an Insoluble Iron Containing Hepcidin–Ferritin Chimeric Monomer Assembled Together with Human Ferritin H/L Chains at Dif...

por Boumaiza, Mohamed, Fhoula, Imene, Carmona, Fernando, Poli, Maura, Asperti, Michela, Gianoncelli, Alessandra, Bertuzzi, Michela, Arosio, Paolo, Marzouki, Mohamed Nejib
Publicado 2021

Sucrosomial(®) Iron Supplementation in Mice: Effects on Blood Parameters, Hepcidin, and Inflammation

por Asperti, Michela, Gryzik, Magdalena, Brilli, Elisa, Castagna, Annalisa, Corbella, Michela, Gottardo, Rossella, Girelli, Domenico, Tarantino, Germano, Arosio, Paolo, Poli, Maura
Publicado 2018

The Antitumor Didox Acts as an Iron Chelator in Hepatocellular Carcinoma Cells

por Asperti, Michela, Cantamessa, Luca, Ghidinelli, Simone, Gryzik, Magdalena, Denardo, Andrea, Giacomini, Arianna, Longhi, Giovanna, Fanzani, Alessandro, Arosio, Paolo, Poli, Maura
Publicado 2019

Iron distribution in different tissues of homozygous Mask (msk/msk) mice and the effects of oral iron treatments

por Asperti, Michela, Brilli, Elisa, Denardo, Andrea, Gryzik, Magdalena, Pagani, Francesca, Busti, Fabiana, Tarantino, Germano, Arosio, Paolo, Girelli, Domenico, Poli, Maura
Publicado 2021

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

por Poli, Maura, Anower-E-Khuda, Ferdous, Asperti, Michela, Ruzzenenti, Paola, Gryzik, Magdalena, Denardo, Andrea, Gordts, Philip L. S. M., Arosio, Paolo, Esko, Jeffrey D.
Publicado 2019

Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity

por Maccarinelli, Federica, Gammella, Elena, Asperti, Michela, Regoni, Maria, Biasiotto, Giorgio, Turco, Emilia, Altruda, Fiorella, Lonardi, Silvia, Cornaghi, Laura, Donetti, Elena, Recalcati, Stefania, Poli, Maura, Finazzi, Dario, Arosio, Paolo, Cairo, Gaetano
Publicado 2014

Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer

por Maccarinelli, Federica, Coltrini, Daniela, Mussi, Silvia, Bugatti, Mattia, Turati, Marta, Chiodelli, Paola, Giacomini, Arianna, De Cillis, Floriana, Cattane, Nadia, Cattaneo, Annamaria, Ligresti, Alessia, Asperti, Michela, Poli, Maura, Vermi, William, Presta, Marco, Ronca, Roberto
Publicado 2023

Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibito...

por Codenotti, Silvia, Zizioli, Daniela, Mignani, Luca, Rezzola, Sara, Tabellini, Giovanna, Parolini, Silvia, Giacomini, Arianna, Asperti, Michela, Poli, Maura, Mandracchia, Delia, Vezzoli, Marika, Bernardi, Simona, Russo, Domenico, Mitola, Stefania, Monti, Eugenio, Triggiani, Luca, Tomasini, Davide, Gastaldello, Stefano, Cassandri, Matteo, Rota, Rossella, Marampon, Francesco, Fanzani, Alessandro
Publicado 2022