Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

por Hodeib, Melissa, Ogrodzinski, Martin P., Vergnes, Laurent, Reue, Karen, Karlan, Beth Y., Lunt, Sophia Y., Aspuria, Paul-Joseph P.
Publicado 2017

Sphingosine kinase 1 is required for TGF-β mediated fibroblast-to-myofibroblast differentiation in ovarian cancer

por Beach, Jessica A., Aspuria, Paul-Joseph P., Cheon, Dong-Joo, Lawrenson, Kate, Agadjanian, Hasmik, Walsh, Christine S., Karlan, Beth Y., Orsulic, Sandra
Publicado 2015

Glucose deprivation elicits phenotypic plasticity via ZEB1-mediated expression of NNMT

por Kanska, Justyna, Aspuria, Paul-Joseph P., Taylor-Harding, Barbie, Spurka, Lindsay, Funari, Vincent, Orsulic, Sandra, Karlan, Beth Y., Wiedemeyer, W. Ruprecht
Publicado 2017

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism

por Aspuria, Paul-Joseph P, Lunt, Sophia Y, Väremo, Leif, Vergnes, Laurent, Gozo, Maricel, Beach, Jessica A, Salumbides, Brenda, Reue, Karen, Wiedemeyer, W Ruprecht, Nielsen, Jens, Karlan, Beth Y, Orsulic, Sandra
Publicado 2014