Rewiring of the Transcription Factor Network in Acute Myeloid Leukemia

por Assi, Salam A, Bonifer, Constanze, Cockerill, Peter N
Publicado 2019

Presaging Critical Residues in Protein interfaces-Web Server (PCRPi-W): A Web Server to Chart Hot Spots in Protein Interfaces

por Segura Mora, Joan, Assi, Salam A., Fernandez-Fuentes, Narcis
Publicado 2010

LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage

por Stanulović, Vesna S., Cauchy, Pierre, Assi, Salam A., Hoogenkamp, Maarten
Publicado 2017

PCRPi: Presaging Critical Residues in Protein interfaces, a new computational tool to chart hot spots in protein interfaces

por Assi, Salam A., Tanaka, Tomoyuki, Rabbitts, Terence H., Fernandez-Fuentes, Narcis
Publicado 2010

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

por Regha, Kakkad, Assi, Salam A., Tsoulaki, Olga, Gilmour, Jane, Lacaud, Georges, Bonifer, Constanze
Publicado 2015

The Co-operation of RUNX1 with LDB1, CDK9 and BRD4 Drives Transcription Factor Complex Relocation During Haematopoietic Specification

por Gilmour, Jane, Assi, Salam A., Noailles, Laura, Lichtinger, Monika, Obier, Nadine, Bonifer, Constanze
Publicado 2018

Wellington-bootstrap: differential DNase-seq footprinting identifies cell-type determining transcription factors

por Piper, Jason, Assi, Salam A., Cauchy, Pierre, Ladroue, Christophe, Cockerill, Peter N., Bonifer, Constanze, Ott, Sascha
Publicado 2015

Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma

por Edginton-White, Benjamin, Cauchy, Pierre, Assi, Salam A., Hartmann, Sylvia, Riggs, Arthur G., Mathas, Stephan, Cockerill, Peter N., Bonifer, Constanze
Publicado 2018

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

por Gilmour, Jane, Assi, Salam A., Jaegle, Ulrike, Kulu, Divine, van de Werken, Harmen, Clarke, Deborah, Westhead, David R., Philipsen, Sjaak, Bonifer, Constanze
Publicado 2014

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

por Ptasinska, Anetta, Pickin, Anna, Assi, Salam A., Chin, Paulynn Suyin, Ames, Luke, Avellino, Roberto, Gröschel, Stephan, Delwel, Ruud, Cockerill, Peter N., Osborne, Cameron S., Bonifer, Constanze
Publicado 2019

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

por Ptasinska, Anetta, Pickin, Anna, Assi, Salam A., Chin, Paulynn Suyin, Ames, Luke, Avellino, Roberto, Gröschel, Stefan, Delwel, Ruud, Cockerill, Peter N., Osborne, Cameron S., Bonifer, Constanze
Publicado 2019

Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate

por Obier, Nadine, Cauchy, Pierre, Assi, Salam A., Gilmour, Jane, Lie-A-Ling, Michael, Lichtinger, Monika, Hoogenkamp, Maarten, Noailles, Laura, Cockerill, Peter N., Lacaud, Georges, Kouskoff, Valerie, Bonifer, Constanze
Publicado 2016

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

por Adamo, Assunta, Chin, Paulynn, Keane, Peter, Assi, Salam A., Potluri, Sandeep, Kellaway, Sophie G., Coleman, Daniel, Ames, Luke, Ptasinska, Anetta, Delwel, H. Ruud, Cockerill, Peter N., Bonifer, Constanze
Publicado 2022

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML

por Loke, Justin, Assi, Salam A., Imperato, Maria Rosaria, Ptasinska, Anetta, Cauchy, Pierre, Grabovska, Yura, Soria, Natalia Martinez, Raghavan, Manoj, Delwel, H. Ruud, Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze
Publicado 2017

The hematopoietic master regulator RUNX1 reshapes the epigenetic landscape at the onset of hematopoiesis

por Lichtinger, Monika, Obier, Nadine, Ingram, Richard, Hannah, Rebecca, Hoogenkamp, Maarten, Vijayabaskar, MS, Wu, Mengchu, Assi, Salam A, Tenen, Daniel G, Westhead, David R, Kouskoff, Valerie, Lacaud, Georges, Göttgens, Berthold, Bonifer, Constanze
Publicado 2013

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

por Coleman, Daniel J.L., Keane, Peter, Luque-Martin, Rosario, Chin, Paulynn S, Blair, Helen, Ames, Luke, Kellaway, Sophie G., Griffin, James, Holmes, Elizabeth, Potluri, Sandeep, Assi, Salam A., Bushweller, John, Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze
Publicado 2023

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis

por Lichtinger, Monika, Ingram, Richard, Hannah, Rebecca, Müller, Dorothee, Clarke, Deborah, Assi, Salam A, Lie-A-Ling, Michael, Noailles, Laura, Vijayabaskar, M S, Wu, Mengchu, Tenen, Daniel G, Westhead, David R, Kouskoff, Valerie, Lacaud, Georges, Göttgens, Berthold, Bonifer, Constanze
Publicado 2012

RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia

por Grinev, Vasily V., Barneh, Farnaz, Ilyushonak, Ilya M., Nakjang, Sirintra, Smink, Job, van Oort, Anita, Clough, Richard, Seyani, Michael, McNeill, Hesta, Reza, Mojgan, Martinez-Soria, Natalia, Assi, Salam A., Ramanouskaya, Tatsiana V., Bonifer, Constanze, Heidenreich, Olaf
Publicado 2021

Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets

por Vijayabaskar, M. S., Goode, Debbie K., Obier, Nadine, Lichtinger, Monika, Emmett, Amber M. L., Abidin, Fatin N. Zainul, Shar, Nisar, Hannah, Rebecca, Assi, Salam A., Lie-A-Ling, Michael, Gottgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Bonifer, Constanze, Westhead, David R.
Publicado 2019

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

por Ptasinska, Anetta, Assi, Salam A., Martinez-Soria, Natalia, Imperato, Maria Rosaria, Piper, Jason, Cauchy, Pierre, Pickin, Anna, James, Sally R., Hoogenkamp, Maarten, Williamson, Dan, Wu, Mengchu, Tenen, Daniel G., Ott, Sascha, Westhead, David R., Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze
Publicado 2014