The Development of Novel Therapies for the Treatment of Acute Myeloid Leukemia (AML)

por Assouline, Sarit, Cocolakis, Eftihia, Borden, Katherine L. B.
Publicado 2012

Phase 1 study of the MDM2 antagonist RO6839921 in patients with acute myeloid leukemia

por Uy, Geoffrey L., Assouline, Sarit, Young, Anne-Marie, Blotner, Steven, Higgins, Brian, Chen, Lin-Chi, Yee, Karen
Publicado 2020

Phenotypical differences and thrombosis rates in secondary erythrocytosis versus polycythemia vera

por Nguyen, Eliane, Harnois, Michaël, Busque, Lambert, Sirhan, Shireen, Assouline, Sarit, Chamaki, Ines, Olney, Harold, Mollica, Luigina, Szuber, Natasha
Publicado 2021

Real-World Treatment Patterns and Clinical Outcomes in Canadian Patients with AML Unfit for First-Line Intensive Chemotherapy

por Sanford, David, Desjardins, Pierre, Leber, Brian, Paulson, Kristjan, Assouline, Sarit, Lembo, Paola M. C., Fournier, Pierre-André, Leitch, Heather A.
Publicado 2022

Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway

por Pera, Benet, Krumsiek, Jan, Assouline, Sarit E., Marullo, Rossella, Patel, Jayeshkumar, Phillip, Jude M., Román, Lidia, Mann, Koren K., Cerchietti, Leandro
Publicado 2018

CT-based radiomics model with machine learning for predicting primary treatment failure in diffuse large B-cell Lymphoma

por Santiago, Raoul, Ortiz Jimenez, Johanna, Forghani, Reza, Muthukrishnan, Nikesh, Del Corpo, Olivier, Karthigesu, Shairabi, Haider, Muhammad Yahya, Reinhold, Caroline, Assouline, Sarit
Publicado 2021

Cross-intolerance with bosutinib after prior tyrosine kinase inhibitors for Philadelphia chromosome-positive leukemia: long-term analysis of a phase I/II study

por Cortes, Jorge E., Lipton, Jeff H., Kota, Vamsi, Castagnetti, Fausto, Assouline, Sarit, Brümmendorf, Tim H., Leip, Eric, Viqueira, Andrea, Gambacorti-Passerini, Carlo
Publicado 2023

An Open-label, Phase II Trial of Entospletinib (GS-9973), a Selective Spleen Tyrosine Kinase Inhibitor, in Diffuse Large B-cell Lymphoma

por Burke, John M., Shustov, Andrei, Essell, James, Patel-Donnelly, Dipti, Yang, Jay, Chen, Robert, Ye, Wei, Shi, Wen, Assouline, Sarit, Sharman, Jeff
Publicado 2018

Caution in using second generation tyrosine kinase inhibitor, especially for first line therapy of chronic myeloid leukemia

por Gambacorti‐Passerini, Carlo, Nicolini, Franck Emmanuel, Larson, Richard A., Aroldi, Andrea, Fontana, Diletta, Piazza, Rocco, le Coutre, Philipp, Antolini, Laura, Assouline, Sarit
Publicado 2022

Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized...

por Assouline, Sarit, Gasiorek, Jadwiga, Bergeron, Julie, Lambert, Caroline, Culjkovic-Kraljacic, Biljana, Cocolakis, Eftihia, Zakaria, Chadi, Szlachtycz, David, Yee, Karen, Borden, Katherine L.B.
Publicado 2023

Systemic cancer therapy: achievements and challenges that lie ahead

por Palumbo, Michael O., Kavan, Petr, Miller, Wilson H., Panasci, Lawrence, Assouline, Sarit, Johnson, Nathalie, Cohen, Victor, Patenaude, Francois, Pollak, Michael, Jagoe, R. Thomas, Batist, Gerald
Publicado 2013

B-cell cytopenia and time to last B-cell-depleting therapy predict response to SARS-COV-2 vaccines in patients with lymphoproliferative disorders

por Tanguay, Mégane, Boutin, Marianne, Laumaea, Annemarie, Salaciak, Matthew, Mendoza, Alma, Cassis, Chantal, Ajjamada, Lissa, Assouline, Sarit, Patenaude, François, Clark, Michael Webster, Finzi, Andrés, Johnson, Nathalie A.
Publicado 2022

Telomerase Contributes to Fludarabine Resistance in Primary Human Leukemic Lymphocytes

por Shawi, May, Chu, Tsz Wai, Martinez-Marignac, Veronica, Yu, Y., Gryaznov, Sergei M., Johnston, James B., Lees-Miller, Susan P., Assouline, Sarit E., Autexier, Chantal, Aloyz, Raquel
Publicado 2013

The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

por Zahreddine, Hiba Ahmad, Culjkovic-Kraljacic, Biljana, Emond, Audrey, Pettersson, Filippa, Midura, Ronald, Lauer, Mark, Del Rincon, Sonia, Cali, Valbona, Assouline, Sarit, Miller, Wilson H, Hascall, Vincent, Borden, Katherine LB
Publicado 2017

An open‐label phase 2 trial of entospletinib in indolent non‐Hodgkin lymphoma and mantle cell lymphoma

por Andorsky, David J., Kolibaba, Kathryn S., Assouline, Sarit, Forero‐Torres, Andres, Jones, Vicky, Klein, Leonard M., Patel‐Donnelly, Dipti, Smith, Mitchell, Ye, Wei, Shi, Wen, Yasenchak, Christopher A., Sharman, Jeff P.
Publicado 2018

Mutated RAS-associating proteins and ERK activation in relapse/refractory diffuse large B cell lymphoma

por Benoit, Alexandre, Bou-Petit, Elisabeth, Chou, Hsiang, Lu, Melissa, Guilbert, Cynthia, Luo, Vincent Mingyi, Assouline, Sarit, Morin, Ryan D., Dmitrienko, Svetlana, Estrada-Tejedor, Roger, Johnson, Nathalie A., Mann, Koren K.
Publicado 2022

Monitoring Response and Resistance to the Novel Arsenical Darinaparsin in an AML Patient

por Nielsen, Torsten H., Johnson, Nathalie, Garnier, Nicolas, Kwan, Stanley, Yao, Lu, Cocolakis, Eftihia, Hébert, Josée, Morgan, Robert A., Paquet, Éric, Callahan, Kevin P., Jordan, Craig T., Assouline, Sarit, Miller, Wilson H., Mann, Koren K.
Publicado 2013

A Phase I dose‐escalation study of DCLL9718S, an antibody‐drug conjugate targeting C‐type lectin‐like molecule‐1 (CLL‐1) in patients with acute myeloid leukemia

por Daver, Naval, Salhotra, Amandeep, Brandwein, Joseph M., Podoltsev, Nikolai A., Pollyea, Daniel A., Jurcic, Joseph G., Assouline, Sarit, Yee, Karen, Li, Mengsong, Pourmohamad, Tony, Samineni, Divya, Sumiyoshi, Teiko, Vaze, Anjali, Dere, Randall C., Ma, Connie, Cooper, James
Publicado 2021

Polatuzumab vedotin plus bendamustine and rituximab in relapsed/refractory DLBCL: survival update and new extension cohort data

por Sehn, Laurie H., Hertzberg, Mark, Opat, Stephen, Herrera, Alex F., Assouline, Sarit, Flowers, Christopher R., Kim, Tae Min, McMillan, Andrew, Ozcan, Muhit, Safar, Violaine, Salles, Gilles, Ku, Grace, Hirata, Jamie, Chang, Yi Meng, Musick, Lisa, Matasar, Matthew J.
Publicado 2022

Polatuzumab Vedotin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma

por Sehn, Laurie H., Herrera, Alex F., Flowers, Christopher R., Kamdar, Manali K., McMillan, Andrew, Hertzberg, Mark, Assouline, Sarit, Kim, Tae Min, Kim, Won Seog, Ozcan, Muhit, Hirata, Jamie, Penuel, Elicia, Paulson, Joseph N., Cheng, Ji, Ku, Grace, Matasar, Matthew J.
Publicado 2020