Modulation of gene expression via overlapping binding sites exerted by ZNF143, Notch1 and THAP11

por Ngondo-Mbongo, Richard Patryk, Myslinski, Evelyne, Aster, Jon C., Carbon, Philippe
Publicado 2013

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia

por Choi, Sung Hee, Severson, Eric, Pear, Warren S., Liu, Xiaole S., Aster, Jon C., Blacklow, Stephen C.
Publicado 2017

A microRNA-mediated regulatory loop modulates NOTCH and MYC oncogenic signals in B and T cell malignancies

por Ortega, Manoela, Bhatnagar, Harshita, Lin, An-Ping, Wang, Long, Aster, Jon C, Sill, Heinz, Aguiar, Ricardo C T
Publicado 2014

Molecular Mechanism of PP2A/B55α Inhibition by IER5

por Cao, Ruili, Jones, Daniel TD, Pan, Li, Wang, Shumei, Rawson, Shaun, Aster, Jon C, Blacklow, Stephen C
Publicado 2023

Gene expression profiling distinguishes prefibrotic from overtly fibrotic myeloproliferative neoplasms and identifies disease subsets with distinct inflammatory signatures

por Wong, Waihay J., Baltay, Michele, Getz, Annaliese, Fuhrman, Kit, Aster, Jon C., Hasserjian, Robert P., Pozdnyakova, Olga
Publicado 2019

Shortwave-infrared meso-patterned imaging enables label-free mapping of tissue water and lipid content

por Zhao, Yanyu, Pilvar, Anahita, Tank, Anup, Peterson, Hannah, Jiang, John, Aster, Jon C., Dumas, John Paul, Pierce, Mark C., Roblyer, Darren
Publicado 2020

Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies

por Oppel, Felix, Tao, Ting, Shi, Hui, Ross, Kenneth N., Zimmerman, Mark W., He, Shuning, Tong, Guangxiang, Aster, Jon C., Look, A. Thomas
Publicado 2019

Notch Ankyrin Repeat Domain Variation Influences Leukemogenesis and Myc Transactivation

por Aster, Jon C., Bodnar, Nick, Xu, Lanwei, Karnell, Fredrick, Milholland, John M., Maillard, Ivan, Histen, Gavin, Nam, Yunsun, Blacklow, Stephen C., Pear, Warren S.
Publicado 2011

Network analysis of gene essentiality in functional genomics experiments

por Jiang, Peng, Wang, Hongfang, Li, Wei, Zang, Chongzhi, Li, Bo, Wong, Yinling J., Meyer, Cliff, Liu, Jun S., Aster, Jon C., Liu, X. Shirley
Publicado 2015

suz12 inactivation in p53- and nf1-deficient zebrafish accelerates the onset of malignant peripheral nerve sheath tumors and expands the spectrum of tumor types

por Oppel, Felix, Ki, Dong H., Zimmerman, Mark W., Ross, Kenneth N., Tao, Ting, Shi, Hui, He, Shuning, Aster, Jon C., Look, A. Thomas
Publicado 2020

A novel Monoclonal Antibody against Notch1 Targets Leukemia-associated Mutant Notch1 and Depletes Therapy Resistant Cancer Stem Cells in Solid Tumors

por Sharma, Ankur, Gadkari, Rupali A, Ramakanth, Satthenapalli V, Padmanabhan, Krishnanand, Madhumathi, Davanam S, Devi, Lakshmi, Appaji, Lingappa, Aster, Jon C, Rangarajan, Annapoorni, Dighe, Rajan R
Publicado 2015

P324: CELL PLASTICITY PREDETERMINES TREATMENT RESPONSE IN T-ALL

por Dimitrova, Valeriya, Frede, Julia, Montanaro, Anna, Potdar, Sayalee, Stuart, Hannah, Sotoudeh, Noori, Van Scoyk, Alexandria, Bhatt, Shruti, Letai, Anthony, Aster, Jon, Lohr, Jens, Knoechel, Birgit
Publicado 2023

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

por Pasqualucci, Laura, Compagno, Mara, Houldsworth, Jane, Monti, Stefano, Grunn, Adina, Nandula, Subhadra V., Aster, Jon C., Murty, Vundavally V., Shipp, Margaret A., Dalla-Favera, Riccardo
Publicado 2006

Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells

por Allman, David, Karnell, Fredrick G., Punt, Jennifer A., Bakkour, Sonia, Xu, Lanwei, Myung, Peggy, Koretzky, Gary A., Pui, John C., Aster, Jon C., Pear, Warren S.
Publicado 2001

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

por Heckl, Dirk, Kowalczyk, Monika S., Yudovich, David, Belizaire, Roger, Puram, Rishi V., McConkey, Marie E., Thielke, Anne, Aster, Jon C., Regev, Aviv, Ebert, Benjamin L.
Publicado 2014

Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset

por Padi, Sathish K.R., Luevano, Libia A., An, Ningfei, Pandey, Ritu, Singh, Neha, Song, Jin H., Aster, Jon C., Yu, Xue-Zhong, Mehrotra, Shikhar, Kraft, Andrew S.
Publicado 2017

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

por Li, Bo, Severson, Eric, Pignon, Jean-Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C., Rodig, Scott, Signoretti, Sabina, Liu, Jun S., Liu, X. Shirley
Publicado 2016

Myeloid neoplasm demonstrating a STAT5B-RARA rearrangement and genetic alterations associated with all-trans retinoic acid resistance identified by a custom next-generation sequenc...

por Kluk, Michael J., Abo, Ryan P., Brown, Ronald D., Kuo, Frank C., Dal Cin, Paola, Pozdnyakova, Olga, Morgan, Elizabeth A., Lindeman, Neal I., DeAngelo, Daniel J., Aster, Jon C.
Publicado 2015

Similar outcomes after haploidentical transplantation with post-transplant cyclophosphamide versus HLA-matched transplantation: a meta-analysis of case-control studies

por Gu, Zhenyang, Wang, Li, Yuan, Lei, Huang, Wenrong, Li, Meng, Guan, Lixun, Wang, Qingyi, Gao, Zhe, Zhao, Shasha, Luo, Lan, Wang, Feiyan, Yang, Nan, Liu, Daihong, Aster, Jon C., Gao, Chunji
Publicado 2017

Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2

por Gordon, Wendy R., Vardar-Ulu, Didem, L'Heureux, Sarah, Ashworth, Todd, Malecki, Michael J., Sanchez-Irizarry, Cheryll, McArthur, Debbie G., Histen, Gavin, Mitchell, Jennifer L., Aster, Jon C., Blacklow, Stephen C.
Publicado 2009