Inhibitor Trapping in N-Myristoyltransferases as a Mechanism for Drug Potency

por Spassov, Danislav S., Atanasova, Mariyana, Doytchinova, Irini
Publicado 2023

Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening

por Spassov, Danislav S., Atanasova, Mariyana, Doytchinova, Irini
Publicado 2022

A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors

por Spassov, Danislav S., Atanasova, Mariyana, Doytchinova, Irini
Publicado 2023

Effects of Curcumin and Ferulic Acid on the Folding of Amyloid-β Peptide

por Salamanova, Evdokiya, Atanasova, Mariyana, Dimitrov, Ivan, Doytchinova, Irini
Publicado 2021

Cellular polyamines condense hyperphosphorylated Tau, triggering Alzheimer’s disease

por Ivanov, Stefan M., Atanasova, Mariyana, Dimitrov, Ivan, Doytchinova, Irini A.
Publicado 2020

Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study

por Doytchinova, Irini, Atanasova, Mariyana, Salamanova, Evdokiya, Ivanov, Stefan, Dimitrov, Ivan
Publicado 2020

Ex Vivo Antioxidant and Cholinesterase Inhibiting Effects of a Novel Galantamine–Curcumin Hybrid on Scopolamine-Induced Neurotoxicity in Mice

por Simeonova, Rumyana, Atanasova, Mariyana, Stavrakov, Georgi, Philipova, Irena, Doytchinova, Irini
Publicado 2022

A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders

por Simeonova, Rumyana, Zheleva, Dimitrina, Valkova, Iva, Stavrakov, Georgi, Philipova, Irena, Atanasova, Mariyana, Doytchinova, Irini
Publicado 2021

A Galantamine–Curcumin Hybrid Decreases the Cytotoxicity of Amyloid-Beta Peptide on SH-SY5Y Cells

por Mladenova, Kirilka, Stavrakov, Georgi, Philipova, Irena, Atanasova, Mariyana, Petrova, Svetla, Doumanov, Jordan, Doytchinova, Irini
Publicado 2021

Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors

por Atanasova, Mariyana, Dimitrov, Ivan, Ivanov, Stefan, Georgiev, Borislav, Berkov, Strahil, Zheleva-Dimitrova, Dimitrina, Doytchinova, Irini
Publicado 2022

Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening

por Stavrakov, Georgi, Philipova, Irena, Lukarski, Atanas, Atanasova, Mariyana, Georgiev, Borislav, Atanasova, Teodora, Konstantinov, Spiro, Doytchinova, Irini
Publicado 2021

Synthesis and DNase I Inhibitory Properties of New Squaramides

por Ruseva, Nina, Sbirkova-Dimitrova, Hristina, Atanasova, Mariyana, Marković, Ana, Šmelcerović, Žaklina, Šmelcerović, Andrija, Bakalova, Adriana, Cherneva, Emiliya
Publicado 2023

Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database

por Doytchinova, Irini, Atanasova, Mariyana, Valkova, Iva, Stavrakov, Georgi, Philipova, Irena, Zhivkova, Zvetanka, Zheleva-Dimitrova, Dimitrina, Konstantinov, Spiro, Dimitrov, Ivan
Publicado 2018

Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors

por Stavrakov, Georgi, Philipova, Irena, Lukarski, Atanas, Atanasova, Mariyana, Zheleva, Dimitrina, Zhivkova, Zvetanka D., Ivanov, Stefan, Atanasova, Teodora, Konstantinov, Spiro, Doytchinova, Irini
Publicado 2020