HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity

por van der Lienden, Martijn J. C., Aten, Jan, Boot, Rolf G., van Eijk, Marco, Aerts, Johannes M. F. G., Kuo, Chi‐Lin
Publicado 2022

Connective tissue growth factor is correlated with peritoneal lymphangiogenesis

por Kinashi, Hiroshi, Toda, Naohiro, Sun, Ting, Nguyen, Tri Q., Suzuki, Yasuhiro, Katsuno, Takayuki, Yokoi, Hideki, Aten, Jan, Mizuno, Masashi, Maruyama, Shoichi, Yanagita, Motoko, Goldschmeding, Roel, Ito, Yasuhiko
Publicado 2019

Renal involvement in a patient with the chronic visceral subtype of acid sphingomyelinase deficiency resembles Fabry disease

por Eskes, Eline C. B., van der Lienden, Martijn J. C., Roelofs, Joris J. T. H., Vogt, Liffert, Aerts, Johannes M. F. G., Aten, Jan, Hollak, Carla E. M.
Publicado 2021

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

por Gaspar, Paulo, Kallemeijn, Wouter W., Strijland, Anneke, Scheij, Saskia, Van Eijk, Marco, Aten, Jan, Overkleeft, Herman S., Balreira, Andrea, Zunke, Friederike, Schwake, Michael, Sá Miranda, Clara, Aerts, Johannes M. F. G.
Publicado 2014

Roles of glomerular endothelial hyaluronan in the development of proteinuria

por Asai, Akimasa, Hatayama, Naoyuki, Kamiya, Keisuke, Yamauchi, Mai, Kinashi, Hiroshi, Yamaguchi, Makoto, Katsuno, Takayuki, Nobata, Hironobu, Watanabe, Kazushi, Wakatsuki, Akihiko, Aten, Jan, Maruyama, Shoichi, Ishimoto, Takuji, Hirai, Shuichi, Naito, Munekazu, Ito, Yasuhiko
Publicado 2021

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

por Marques, André R. A., Gabriel, Tanit L., Aten, Jan, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Claessen, Nike, Alfonso, Pilar, Irún, Pilar, Giraldo, Pilar, Aerts, Johannes M. F. G., van Eijk, Marco
Publicado 2016

Distinct osmoregulatory responses to sodium loading in patients with altered glycosaminoglycan structure: a randomized cross-over trial

por Wenstedt, Eliane F. E., Oppelaar, Jetta J., Besseling, Stijn, Rorije, Nienke M. G., Olde Engberink, Rik H. G., Oosterhof, Arie, van Kuppevelt, Toin H., van den Born, Bert-Jan H., Aten, Jan, Vogt, Liffert
Publicado 2021

Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism

por Lombardo, Elisa, van Roomen, Cindy P. A. A., van Puijvelde, Gijs H., Ottenhoff, Roelof, van Eijk, Marco, Aten, Jan, Kuiper, Johan, Overkleeft, Herman S., Groen, Albert K., Verhoeven, Arthur J., Aerts, Johannes M. F. G., Bietrix, Florence
Publicado 2012

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

por van der Lienden, Martijn J. C., Aten, Jan, Marques, André R. A., Waas, Ingeborg S. E., Larsen, Per W. B., Claessen, Nike, van der Wel, Nicole N., Ottenhoff, Roelof, van Eijk, Marco, Aerts, Johannes M. F. G.
Publicado 2021

Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation

por van Eijk, Marco, Aten, Jan, Bijl, Nora, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Dubbelhuis, Peter F., Seeman, Ingar, Ghauharali-van der Vlugt, Karen, Overkleeft, Hermen S., Arbeeny, Cynthia, Groen, Albert K., Aerts, Johannes M. F. G.
Publicado 2009

Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction

por Gerritsen, Karin G. F., Leeuwis, Jan Willem, Koeners, Maarten P., Bakker, Stephan J. L., van Oeveren, Willem, Aten, Jan, Tarnow, Lise, Rossing, Peter, Wetzels, Jack F. M., Joles, Jaap A., Kok, Robbert Jan, Goldschmeding, Roel, Nguyen, Tri Q.
Publicado 2015

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity

por Tol, Marc J., Ottenhoff, Roelof, van Eijk, Marco, Zelcer, Noam, Aten, Jan, Houten, Sander M., Geerts, Dirk, van Roomen, Cindy, Bierlaagh, Marlou C., Scheij, Saskia, Hoeksema, Marten A., Aerts, Johannes M., Bogan, Jonathan S., Dorn, Gerald W., Argmann, Carmen A., Verhoeven, Arthur J.
Publicado 2016

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice

por Marques, André R. A., Aten, Jan, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Herrera Moro, Daniela, Claessen, Nike, Vinueza Veloz, María Fernanda, Zhou, Kuikui, Lin, Zhanmin, Mirzaian, Mina, Boot, Rolf G., De Zeeuw, Chris I., Overkleeft, Herman S., Yildiz, Yildiz, Aerts, Johannes M. F. G.
Publicado 2015

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

por Herrera Moro Chao, Daniela, Kallemeijn, Wouter W., Marques, Andre R. A., Orre, Marie, Ottenhoff, Roelof, van Roomen, Cindy, Foppen, Ewout, Renner, Maria C., Moeton, Martina, van Eijk, Marco, Boot, Rolf G., Kamphuis, Willem, Hol, Elly M., Aten, Jan, Overkleeft, Hermen S., Kalsbeek, Andries, Aerts, Johannes M. F. G.
Publicado 2015

Epicardial and endothelial cell activation concurs with extracellular matrix remodeling in atrial fibrillation

por van den Berg, Nicoline W. E., Kawasaki, Makiri, Fabrizi, Benedetta, Nariswari, Fransisca A., Verduijn, Arianne C., Neefs, Jolien, Wesselink, Robin, Al‐Shama, Rushd F. M., van der Wal, Allard C., de Boer, Onno J., Aten, Jan, Driessen, Antoine H. G., Jongejan, Aldo, de Groot, Joris R.
Publicado 2021