Cyclic oligoadenylate signaling and regulation by ring nucleases during type III CRISPR defense

por Athukoralage, Januka S., White, Malcolm F.
Publicado 2021

Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence

por Samolygo, Aleksei, Athukoralage, Januka S, Graham, Shirley, White, Malcolm F
Publicado 2020

Control of cyclic oligoadenylate synthesis in a type III CRISPR system

por Rouillon, Christophe, Athukoralage, Januka S, Graham, Shirley, Grüschow, Sabine, White, Malcolm F
Publicado 2018

Ring nucleases deactivate Type III CRISPR ribonucleases by degrading cyclic oligoadenylate

por Athukoralage, Januka S, Rouillon, Christophe, Graham, Shirley, Grüschow, Sabine, White, Malcolm F
Publicado 2018

A Type III CRISPR Ancillary Ribonuclease Degrades Its Cyclic Oligoadenylate Activator

por Athukoralage, Januka S., Graham, Shirley, Grüschow, Sabine, Rouillon, Christophe, White, Malcolm F.
Publicado 2019

Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence

por Grüschow, Sabine, Athukoralage, Januka S, Graham, Shirley, Hoogeboom, Tess, White, Malcolm F
Publicado 2019

The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling

por Athukoralage, Januka S, Graham, Shirley, Rouillon, Christophe, Grüschow, Sabine, Czekster, Clarissa M, White, Malcolm F
Publicado 2020

Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

por Athukoralage, Januka S, McQuarrie, Stuart, Grüschow, Sabine, Graham, Shirley, Gloster, Tracey M, White, Malcolm F
Publicado 2020

A viral ring nuclease anti-CRISPR subverts type III CRISPR immunity

por Athukoralage, Januka S, McMahon, Stephen A, Zhang, Changyi, Grüschow, Sabine, Graham, Shirley, Krupovic, Mart, Whitaker, Rachel J, Gloster, Tracey M, White, Malcolm F
Publicado 2020