Mutant HRAS as novel target for MEK and mTOR inhibitors

por Kiessling, Michael K., Curioni-Fontecedro, Alessandra, Samaras, Panagiotis, Atrott, Kirstin, Cosin-Roger, Jesus, Lang, Silvia, Scharl, Michael, Rogler, Gerhard
Publicado 2015

Activation of Protein Tyrosine Phosphatase Non-Receptor Type 2 by Spermidine Exerts Anti-Inflammatory Effects in Human THP-1 Monocytes and in a Mouse Model of Acute Colitis

por Morón, Belén, Spalinger, Marianne, Kasper, Stephanie, Atrott, Kirstin, Frey-Wagner, Isabelle, Fried, Michael, McCole, Declan F., Rogler, Gerhard, Scharl, Michael
Publicado 2013

Doxycycline, metronidazole and isotretinoin: Do they modify microRNA/mRNA expression profiles and function in murine T-cells?

por Becker, Eugenia, Bengs, Susan, Aluri, Sirisha, Opitz, Lennart, Atrott, Kirstin, Stanzel, Claudia, Castro, Pedro A. Ruiz, Rogler, Gerhard, Frey-Wagner, Isabelle
Publicado 2016

Titanium Dioxide Presents a Different Profile in Dextran Sodium Sulphate-Induced Experimental Colitis in Mice Lacking the IBD Risk Gene Ptpn2 in Myeloid Cells

por Conde, Javier, Schwarzfischer, Marlene, Katkeviciute, Egle, Häfliger, Janine, Niechcial, Anna, Brillant, Nathalie, Manzini, Roberto, Bäbler, Katharina, Atrott, Kirstin, Lang, Silvia, Scharl, Michael
Publicado 2021

Glycoprotein (GP)96 Is Essential for Maintaining Intestinal Epithelial Architecture by Supporting Its Self-Renewal Capacity

por Häfliger, Janine, Schwarzfischer, Marlene, Atrott, Kirstin, Stanzel, Claudia, Morsy, Yasser, Wawrzyniak, Marcin, Lang, Silvia, Valenta, Tomas, Basler, Konrad, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R.
Publicado 2022

Spermidine Ameliorates Colitis via Induction of Anti-Inflammatory Macrophages and Prevention of Intestinal Dysbiosis

por Niechcial, Anna, Schwarzfischer, Marlene, Wawrzyniak, Marcin, Atrott, Kirstin, Laimbacher, Andrea, Morsy, Yasser, Katkeviciute, Egle, Häfliger, Janine, Westermann, Patrick, Akdis, Cezmi A, Scharl, Michael, Spalinger, Marianne R
Publicado 2023

Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance

por Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Busenhart, Philipp, Gottier, Claudia, Mrdjen, Dunja, Komuczki, Juliana, Wawrzyniak, Marcin, Lang, Silvia, Atrott, Kirstin, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R.
Publicado 2020

Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N(2) in Dendritic Cells to Protect from Elevated Colitis

por Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Niechcial, Anna, Riggs, Julianne B., Wawrzyniak, Marcin, Atrott, Kirstin, van de Sande, Marnix, Lang, Silvia, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R.
Publicado 2021

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

por Ruiz, Pedro A, Morón, Belen, Becker, Helen M, Lang, Silvia, Atrott, Kirstin, Spalinger, Marianne R, Scharl, Michael, Wojtal, Kacper A, Fischbeck-Terhalle, Anne, Frey-Wagner, Isabelle, Hausmann, Martin, Kraemer, Thomas, Rogler, Gerhard
Publicado 2017

Gp96 deficiency affects TLR4 functionality and impairs ERK and p38 phosphorylation

por Cosin-Roger, Jesus, Spalinger, Marianne R., Ruiz, Pedro A., Stanzel, Claudia, Terhalle, Anne, Wolfram, Lutz, Melhem, Hassan, Atrott, Kirstin, Lang, Silvia, Frey-Wagner, Isabelle, Fried, Michael, Scharl, Michael, Hausmann, Martin, Rogler, Gerhard
Publicado 2018

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

por Cosin-Roger, Jesus, Simmen, Simona, Melhem, Hassan, Atrott, Kirstin, Frey-Wagner, Isabelle, Hausmann, Martin, de Vallière, Cheryl, Spalinger, Marianne R., Spielmann, Patrick, Wenger, Roland H., Zeitz, Jonas, Vavricka, Stephan R., Rogler, Gerhard, Ruiz, Pedro A.
Publicado 2017

Inhibition of integrin αvβ6 sparks T-cell antitumor response and enhances immune checkpoint blockade therapy in colorectal cancer

por Busenhart, Philipp, Montalban-Arques, Ana, Katkeviciute, Egle, Morsy, Yasser, Van Passen, Chiara, Hering, Larissa, Atrott, Kirstin, Lang, Silvia, Garzon, Jesus Francisco Glaus, Naschberger, Elisabeth, Hartmann, Arndt, Rogler, Gerhard, Stürzl, Michael, Spalinger, Marianne Rebecca, Scharl, Michael
Publicado 2022

Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein–Coupled Receptor OGR1 (GPR68)

por de Vallière, Cheryl, Cosin-Roger, Jesus, Simmen, Simona, Atrott, Kirstin, Melhem, Hassan, Zeitz, Jonas, Madanchi, Mehdi, Tcymbarevich, Irina, Fried, Michael, Kullak-Ublick, Gerd A., Vavricka, Stephan R., Misselwitz, Benjamin, Seuwen, Klaus, Wagner, Carsten A., Eloranta, Jyrki J., Rogler, Gerhard, Ruiz, Pedro A.
Publicado 2016

Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis

por Raselli, Tina, Hearn, Tom, Wyss, Annika, Atrott, Kirstin, Peter, Alain, Frey-Wagner, Isabelle, Spalinger, Marianne R., Maggio, Ewerton M., Sailer, Andreas W., Schmitt, Johannes, Schreiner, Philipp, Moncsek, Anja, Mertens, Joachim, Scharl, Michael, Griffiths, William J., Bueter, Marco, Geier, Andreas, Rogler, Gerhard, Wang, Yuqin, Misselwitz, Benjamin
Publicado 2019

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22

por Spalinger, Marianne R., Kasper, Stephanie, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Vavricka, Stephan R., Scharl, Sylvie, Gutte, Petrus M., Grütter, Markus G., Beer, Hans-Dietmar, Contassot, Emmanuel, Chan, Andrew C., Dai, Xuezhi, Rawlings, David J., Mair, Florian, Becher, Burkhard, Falk, Werner, Fried, Michael, Rogler, Gerhard, Scharl, Michael
Publicado 2023