Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

por Curion, Fabiola, Handel, Adam E, Attar, Moustafa, Gallone, Giuseppe, Bowden, Rory, Cader, M. Zameel, Clark, Michael B
Publicado 2020

Comparative transcriptomics between species attributes reactogenicity pathways induced by the capsular group B meningococcal vaccine, 4CMenB, to the membrane-bound endotoxin of its...

por Sheerin, Dylan, O’Connor, Daniel, Dold, Christina, Clutterbuck, Elizabeth, Attar, Moustafa, Rollier, Christine S., Sadarangani, Manish, Pollard, Andrew J.
Publicado 2019

Improved workflows for high throughput library preparation using the transposome-based nextera system

por Lamble, Sarah, Batty, Elizabeth, Attar, Moustafa, Buck, David, Bowden, Rory, Lunter, Gerton, Crook, Derrick, El-Fahmawi, Bassam, Piazza, Paolo
Publicado 2013

RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus

por Jansen, Kathrin, Shikama-Dorn, Noriko, Attar, Moustafa, Maio, Stefano, Lopopolo, Maria, Buck, David, Holländer, Georg A., Sansom, Stephen N.
Publicado 2021

A practical solution for preserving single cells for RNA sequencing

por Attar, Moustafa, Sharma, Eshita, Li, Shuqiang, Bryer, Claire, Cubitt, Laura, Broxholme, John, Lockstone, Helen, Kinchen, James, Simmons, Alison, Piazza, Paolo, Buck, David, Livak, Kenneth J., Bowden, Rory
Publicado 2018

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

por Zec, Kristina, Schonfeldova, Barbora, Ai, Zhichao, Van Grinsven, Erinke, Pirgova, Gabriela, Eames, Hayley L., Berthold, Dorothée L., Attar, Moustafa, Compeer, Ewoud B., Arnon, Tal I., Udalova, Irina A.
Publicado 2023

Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis

por Yazicioglu, Yavuz F., Marin, Eros, Sandhu, Ciaran, Galiani, Silvia, Raza, Iwan G. A., Ali, Mohammad, Kronsteiner, Barbara, Compeer, Ewoud B., Attar, Moustafa, Dunachie, Susanna J., Dustin, Michael L., Clarke, Alexander J.
Publicado 2023

Dual RNA sequencing reveals dendritic cell reprogramming in response to typhoidal Salmonella invasion

por Aulicino, Anna, Antanaviciute, Agne, Frost, Joe, Sousa Geros, Ana, Mellado, Esther, Attar, Moustafa, Jagielowicz, Marta, Hublitz, Philip, Sinz, Julia, Preciado-Llanes, Lorena, Napolitani, Giorgio, Bowden, Rory, Koohy, Hashem, Drakesmith, Hal, Simmons, Alison
Publicado 2022

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

por Lang, Charmaine, Campbell, Kieran R., Ryan, Brent J., Carling, Phillippa, Attar, Moustafa, Vowles, Jane, Perestenko, Olga V., Bowden, Rory, Baig, Fahd, Kasten, Meike, Hu, Michele T., Cowley, Sally A., Webber, Caleb, Wade-Martins, Richard
Publicado 2019

IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance and diversity of intra-tumoral stem-like T cells

por Mazet, Julie M., Mahale, Jagdish N., Tong, Orion, Watson, Robert A., Lechuga‐Vieco, Ana Victoria, Pirgova, Gabriela, Lau, Vivian W. C., Attar, Moustafa, Koneva, Lada A., Sansom, Stephen N., Fairfax, Benjamin P., Gérard, Audrey
Publicado 2023

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons

por Zambon, Federico, Cherubini, Marta, Fernandes, Hugo J R, Lang, Charmaine, Ryan, Brent J, Volpato, Viola, Bengoa-Vergniory, Nora, Vingill, Siv, Attar, Moustafa, Booth, Heather D E, Haenseler, Walther, Vowles, Jane, Bowden, Rory, Webber, Caleb, Cowley, Sally A, Wade-Martins, Richard
Publicado 2019

Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites

por MacLean, Andrew J., Richmond, Niamh, Koneva, Lada, Attar, Moustafa, Medina, Cesar A.P., Thornton, Emily E., Gomes, Ariane Cruz, El-Turabi, Aadil, Bachmann, Martin F., Rijal, Pramila, Tan, Tiong Kit, Townsend, Alain, Sansom, Stephen N., Bannard, Oliver, Arnon, Tal I.
Publicado 2022

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease

por Kinchen, James, Chen, Hannah H., Parikh, Kaushal, Antanaviciute, Agne, Jagielowicz, Marta, Fawkner-Corbett, David, Ashley, Neil, Cubitt, Laura, Mellado-Gomez, Esther, Attar, Moustafa, Sharma, Eshita, Wills, Quin, Bowden, Rory, Richter, Felix C., Ahern, David, Puri, Kamal D., Henault, Jill, Gervais, Francois, Koohy, Hashem, Simmons, Alison
Publicado 2018

A Modified RNA-Seq Approach for Whole Genome Sequencing of RNA Viruses from Faecal and Blood Samples

por Batty, Elizabeth M., Wong, T. H. Nicholas, Trebes, Amy, Argoud, Karène, Attar, Moustafa, Buck, David, Ip, Camilla L. C., Golubchik, Tanya, Cule, Madeleine, Bowden, Rory, Manganis, Charis, Klenerman, Paul, Barnes, Eleanor, Walker, A. Sarah, Wyllie, David H., Wilson, Daniel J., Dingle, Kate E., Peto, Tim E. A., Crook, Derrick W., Piazza, Paolo
Publicado 2013

Distinct fibroblast subsets drive inflammation and damage in arthritis

por Croft, Adam P, Campos, Joana, Jansen, Kathrin, Turner, Jason D, Marshall, Jennifer, Attar, Moustafa, Savary, Loriane, Wehmeyer, Corinna, Naylor, Amy J., Kemble, Samuel, Begum, Jenefa, Duerholz, Kerstin, Perlman, Harris, Barone, Francesca, McGettrick, Helen M, Fearon, Douglas T, Wei, Kevin, Raychaudhuri, Soumya, Korsunsky, Ilya, Brenner, Michael B, Coles, Mark, Sansom, Stephen N, Filer, Andrew, Buckley, Christopher D
Publicado 2019

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

por Céspedes, Pablo F., Jainarayanan, Ashwin, Fernández-Messina, Lola, Valvo, Salvatore, Saliba, David G., Kurz, Elke, Kvalvaag, Audun, Chen, Lina, Ganskow, Charity, Colin-York, Huw, Fritzsche, Marco, Peng, Yanchun, Dong, Tao, Johnson, Errin, Siller-Farfán, Jesús A., Dushek, Omer, Sezgin, Erdinc, Peacock, Ben, Law, Alice, Aubert, Dimitri, Engledow, Simon, Attar, Moustafa, Hester, Svenja, Fischer, Roman, Sánchez-Madrid, Francisco, Dustin, Michael L.
Publicado 2022

IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

por Friedrich, Matthias, Pohin, Mathilde, Jackson, Matthew A., Korsunsky, Ilya, Bullers, Samuel J., Rue-Albrecht, Kevin, Christoforidou, Zoe, Sathananthan, Dharshan, Thomas, Tom, Ravindran, Rahul, Tandon, Ruchi, Peres, Raphael Sanches, Sharpe, Hannah, Wei, Kevin, Watts, Gerald F. M., Mann, Elizabeth H., Geremia, Alessandra, Attar, Moustafa, McCuaig, Sarah, Thomas, Lloyd, Collantes, Elena, Uhlig, Holm H., Sansom, Stephen N., Easton, Alistair, Raychaudhuri, Soumya, Travis, Simon P., Powrie, Fiona M.
Publicado 2021

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

por Volpato, Viola, Smith, James, Sandor, Cynthia, Ried, Janina S., Baud, Anna, Handel, Adam, Newey, Sarah E., Wessely, Frank, Attar, Moustafa, Whiteley, Emma, Chintawar, Satyan, Verheyen, An, Barta, Thomas, Lako, Majlinda, Armstrong, Lyle, Muschet, Caroline, Artati, Anna, Cusulin, Carlo, Christensen, Klaus, Patsch, Christoph, Sharma, Eshita, Nicod, Jerome, Brownjohn, Philip, Stubbs, Victoria, Heywood, Wendy E., Gissen, Paul, De Filippis, Roberta, Janssen, Katharina, Reinhardt, Peter, Adamski, Jerzy, Royaux, Ines, Peeters, Pieter J., Terstappen, Georg C., Graf, Martin, Livesey, Frederick J., Akerman, Colin J., Mills, Kevin, Bowden, Rory, Nicholson, George, Webber, Caleb, Cader, M. Zameel, Lakics, Viktor
Publicado 2018

An immunodominant NP(105–113)-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

por Peng, Yanchun, Felce, Suet Ling, Dong, Danning, Penkava, Frank, Mentzer, Alexander J., Yao, Xuan, Liu, Guihai, Yin, Zixi, Chen, Ji-Li, Lu, Yongxu, Wellington, Dannielle, Wing, Peter A. C., Dominey-Foy, Delaney C. C., Jin, Chen, Wang, Wenbo, Hamid, Megat Abd, Fernandes, Ricardo A., Wang, Beibei, Fries, Anastasia, Zhuang, Xiaodong, Ashley, Neil, Rostron, Timothy, Waugh, Craig, Sopp, Paul, Hublitz, Philip, Beveridge, Ryan, Tan, Tiong Kit, Dold, Christina, Kwok, Andrew J., Rich-Griffin, Charlotte, Dejnirattisa, Wanwisa, Liu, Chang, Kurupati, Prathiba, Nassiri, Isar, Watson, Robert A., Tong, Orion, Taylor, Chelsea A., Kumar Sharma, Piyush, Sun, Bo, Curion, Fabiola, Revale, Santiago, Garner, Lucy C., Jansen, Kathrin, Ferreira, Ricardo C., Attar, Moustafa, Fry, Jeremy W., Russell, Rebecca A., Stauss, Hans J., James, William, Townsend, Alain, Ho, Ling-Pei, Klenerman, Paul, Mongkolsapaya, Juthathip, Screaton, Gavin R., Dendrou, Calliope, Sansom, Stephen N., Bashford-Rogers, Rachael, Chain, Benny, Smith, Geoffrey L., McKeating, Jane A., Fairfax, Benjamin P., Bowness, Paul, McMichael, Andrew J., Ogg, Graham, Knight, Julian C., Dong, Tao
Publicado 2021

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

por Taylor, Jenny C, Martin, Hilary C, Lise, Stefano, Broxholme, John, Cazier, Jean-Baptiste, Rimmer, Andy, Kanapin, Alexander, Lunter, Gerton, Fiddy, Simon, Allan, Chris, Aricescu, A. Radu, Attar, Moustafa, Babbs, Christian, Becq, Jennifer, Beeson, David, Bento, Celeste, Bignell, Patricia, Blair, Edward, Buckle, Veronica J, Bull, Katherine, Cais, Ondrej, Cario, Holger, Chapel, Helen, Copley, Richard R, Cornall, Richard, Craft, Jude, Dahan, Karin, Davenport, Emma E, Dendrou, Calliope, Devuyst, Olivier, Fenwick, Aimée L, Flint, Jonathan, Fugger, Lars, Gilbert, Rodney D, Goriely, Anne, Green, Angie, Greger, Ingo H., Grocock, Russell, Gruszczyk, Anja V, Hastings, Robert, Hatton, Edouard, Higgs, Doug, Hill, Adrian, Holmes, Chris, Howard, Malcolm, Hughes, Linda, Humburg, Peter, Johnson, David, Karpe, Fredrik, Kingsbury, Zoya, Kini, Usha, Knight, Julian C, Krohn, Jonathan, Lamble, Sarah, Langman, Craig, Lonie, Lorne, Luck, Joshua, McCarthy, Davis, McGowan, Simon J, McMullin, Mary Frances, Miller, Kerry A, Murray, Lisa, Németh, Andrea H, Nesbit, M Andrew, Nutt, David, Ormondroyd, Elizabeth, Oturai, Annette Bang, Pagnamenta, Alistair, Patel, Smita Y, Percy, Melanie, Petousi, Nayia, Piazza, Paolo, Piret, Sian E, Polanco-Echeverry, Guadalupe, Popitsch, Niko, Powrie, Fiona, Pugh, Chris, Quek, Lynn, Robbins, Peter A, Robson, Kathryn, Russo, Alexandra, Sahgal, Natasha, van Schouwenburg, Pauline A, Schuh, Anna, Silverman, Earl, Simmons, Alison, Sørensen, Per Soelberg, Sweeney, Elizabeth, Taylor, John, Thakker, Rajesh V, Tomlinson, Ian, Trebes, Amy, Twigg, Stephen RF, Uhlig, Holm H, Vyas, Paresh, Vyse, Tim, Wall, Steven A, Watkins, Hugh, Whyte, Michael P, Witty, Lorna, Wright, Ben, Yau, Chris, Buck, David, Humphray, Sean, Ratcliffe, Peter J, Bell, John I, Wilkie, Andrew OM, Bentley, David, Donnelly, Peter, McVean, Gilean
Publicado 2015