Hedgehog pathway inhibition and the race against tumor evolution

por Atwood, Scott X., Chang, Anne Lynn S., Oro, Anthony E.
Publicado 2012

Divergent Resistance Mechanisms to Immunotherapy Explain Responses in Different Skin Cancers

por Dollinger, Emmanuel, Bergman, Daniel, Zhou, Peijie, Atwood, Scott X., Nie, Qing
Publicado 2020

Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration

por Woo, Wei-Meng, Atwood, Scott X., Zhen, Hanson H., Oro, Anthony E.
Publicado 2013

Leveraging gene correlations in single cell transcriptomic data

por Silkwood, Kai, Dollinger, Emmanuel, Gervin, Josh, Atwood, Scott, Nie, Qing, Lander, Arthur D.
Publicado 2023

Gli activation by aPKC iota/lambda regulates basal cell carcinoma growth

por Atwood, Scott X., Li, Mischa, Lee, Alex, Tang, Jean Y., Oro, Anthony E.
Publicado 2013

ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1

por Bardwell, A Jane, Wu, Beibei, Sarin, Kavita Y, Waterman, Marian L, Atwood, Scott X, Bardwell, Lee
Publicado 2022

Identification of Genes Promoting Skin Youthfulness by Genome-Wide Association Study

por Chang, Anne L.S., Atzmon, Gil, Bergman, Aviv, Brugmann, Samantha, Atwood, Scott X, Chang, Howard Y, Barzilai, Nir
Publicado 2014

PI3K Promotes Basal Cell Carcinoma Growth Through Kinase-Induced p21 Degradation

por Chow, Rachel Y., Jeon, Ung Seop, Levee, Taylor M., Kaur, Gurleen, Cedeno, Daniel P., Doan, Linda T., Atwood, Scott X.
Publicado 2021

Screening cell–cell communication in spatial transcriptomics via collective optimal transport

por Cang, Zixuan, Zhao, Yanxiang, Almet, Axel A., Stabell, Adam, Ramos, Raul, Plikus, Maksim V., Atwood, Scott X., Nie, Qing
Publicado 2023

Tumor-Derived Suppressor of Fused Mutations Reveal Hedgehog Pathway Interactions

por Urman, Nicole M., Mirza, Amar, Atwood, Scott X., Whitson, Ramon J., Sarin, Kavita Y., Tang, Jean Y., Oro, Anthony E.
Publicado 2016

Rolling the genetic dice: neutral and deleterious Smoothened mutations in drug-resistant basal cell carcinoma

por Atwood, Scott X., Sarin, Kavita Y., Li, Jiang R., Yao, Catherine, Urman, Nicole M., Chang, Anne Lynn S., Tang, Jean Y., Oro, Anthony E.
Publicado 2015

Actin polymerization controls cilia-mediated signaling

por Drummond, Michael L., Li, Mischa, Tarapore, Eric, Nguyen, Tuyen T.L., Barouni, Baina J., Cruz, Shaun, Tan, Kevin C., Oro, Anthony E., Atwood, Scott X.
Publicado 2018

Single-cell transcriptomics of human-skin-equivalent organoids

por Stabell, Adam R., Lee, Grace E., Jia, Yunlong, Wong, Kirsten N., Wang, Shuxiong, Ling, Ji, Nguyen, Sandrine D., Sen, George L., Nie, Qing, Atwood, Scott X.
Publicado 2023

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

por Veniaminova, Natalia A., Jia, Yunlong, Hartigan, Adrien M., Huyge, Thomas J., Tsai, Shih-Ying, Grachtchouk, Marina, Nakagawa, Seitaro, Dlugosz, Andrzej A., Atwood, Scott X., Wong, Sunny Y.
Publicado 2023

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

por Veniaminova, Natalia A., Jia, Yunlong Y., Hartigan, Adrien M., Huyge, Thomas J., Tsai, Shih-Ying, Grachtchouk, Marina, Nakagawa, Seitaro, Dlugosz, Andrzej A., Atwood, Scott X., Wong, Sunny Y.
Publicado 2023

AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma

por Yao, Catherine D., Haensel, Daniel, Gaddam, Sadhana, Patel, Tiffany, Atwood, Scott X., Sarin, Kavita Y., Whitson, Ramon J., McKellar, Siegen, Shankar, Gautam, Aasi, Sumaira, Rieger, Kerri, Oro, Anthony E.
Publicado 2020

Single cell transcriptomics of human epidermis identifies basal stem cell transition states

por Wang, Shuxiong, Drummond, Michael L., Guerrero-Juarez, Christian F., Tarapore, Eric, MacLean, Adam L., Stabell, Adam R., Wu, Stephanie C., Gutierrez, Guadalupe, That, Bao T., Benavente, Claudia A., Nie, Qing, Atwood, Scott X.
Publicado 2020

Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment

por Guerrero-Juarez, Christian F., Lee, Gun Ho, Liu, Yingzi, Wang, Shuxiong, Karikomi, Matthew, Sha, Yutong, Chow, Rachel Y., Nguyen, Tuyen T. L., Iglesias, Venus Sosa, Aasi, Sumaira, Drummond, Michael L., Nie, Qing, Sarin, Kavita, Atwood, Scott X.
Publicado 2022

Non-canonical hedgehog pathway activation by MKL1/SRF promotes drug-resistance in basal cell carcinomas

por Whitson, Ramon J., Lee, Alex, Urman, Nicole M., Mirza, Amar, Yao, Catherine Y., Brown, Alexander S., Li, Jiang R., Shankar, Gautam, Fry, Micah A., Atwood, Scott X., Hollmig, S. Tyler, Aasi, Sumaira Z., Sarin, Kavita Y., Epstein, Ervin H., Tang, Jean Y., Oro, Anthony E.
Publicado 2018

Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition

por Tang, Yujie, Gholamin, Sharareh, Schubert, Simone, Willardson, Minde I., Lee, Alex, Bandopadhayay, Pratiti, Bergthold, Guillame, Masoud, Sabran, Nguyen, Brian, Vue, Nujsaubnusi, Balansay, Brianna, Yu, Furong, Oh, Sekyung, Woo, Pamelyn, Chen, Spenser, Ponnuswami, Anitha, Monje, Michelle, Atwood, Scott X., Whitson, Ramon J., Mitra, Siddhartha, Cheshier, Samuel H., Qi, Jun, Beroukhim, Rameen, Tang, Jean Y., Wechsler-Reya, Rob, Oro, Anthony E., Link, Brian A., Bradner, James E., Cho, Yoon-Jae
Publicado 2014