RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice

por Delbridge, Alex R.D., Pang, Swee Heng Milon, Vandenberg, Cassandra J., Grabow, Stephanie, Aubrey, Brandon J., Tai, Lin, Herold, Marco J., Strasser, Andreas
Publicado 2016

The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL

por Delbridge, Alex RD, Aubrey, Brandon J, Hyland, Craig, Bernardini, Jonathan P, Di Rago, Ladina, Garnier, Jean-Marc, Lessene, Guillaume, Strasser, Andreas, Alexander, Warren S, Grabow, Stephanie
Publicado 2017

Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development

por Aubrey, Brandon J., Janic, Ana, Chen, Yunshun, Chang, Catherine, Lieschke, Elizabeth C., Diepstraten, Sarah T., Kueh, Andrew J., Bernardini, Jonathan P., Dewson, Grant, O'Reilly, Lorraine A., Whitehead, Lachlan, Voss, Anne K., Smyth, Gordon K., Strasser, Andreas, Kelly, Gemma L.
Publicado 2018

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

por Kelly, Gemma L., Grabow, Stephanie, Glaser, Stefan P., Fitzsimmons, Leah, Aubrey, Brandon J., Okamoto, Toru, Valente, Liz J., Robati, Mikara, Tai, Lin, Fairlie, W. Douglas, Lee, Erinna F., Lindstrom, Mikael S., Wiman, Klas G., Huang, David C.S., Bouillet, Philippe, Rowe, Martin, Rickinson, Alan B., Herold, Marco J., Strasser, Andreas
Publicado 2014

IKAROS and MENIN Coordinate Therapeutically Actionable Leukaemogenic Gene Expression in MLL-r Acute Myeloid Leukaemia

por Aubrey, Brandon J., Cutler, Jevon A., Bourgeois, Wallace, Donovan, Katherine A., Gu, Shengqing, Hatton, Charlie, Perlee, Sarah, Perner, Florian, Rahnamoun, Homa, Theall, Alexandra C. P., Henrich, Jill A., Zhu, Qian, Nowak, Radosław P., Kim, Young Joon, Parvin, Salma, Cremer, Anjali, Olsen, Sarah Naomi, Eleuteri, Nicholas A., Pikman, Yana, McGeehan, Gerard M., Stegmaier, Kimberly, Letai, Anthony, Fischer, Eric S., Liu, X. Shirley, Armstrong, Scott A.
Publicado 2022