The dual face of NAMPT: Intracellular/extracellular protein and diagnostic/therapeutic target in cancer

por Audrito, Valentina
Publicado 2020

NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation

por Audrito, Valentina, Messana, Vincenzo Gianluca, Deaglio, Silvia
Publicado 2020

The Extracellular NADome Modulates Immune Responses

por Audrito, Valentina, Messana, Vincenzo Gianluca, Brandimarte, Lorenzo, Deaglio, Silvia
Publicado 2021

Metabolic Interplay between the Immune System and Melanoma Cells: Therapeutic Implications

por Indini, Alice, Grossi, Francesco, Mandalà, Mario, Taverna, Daniela, Audrito, Valentina
Publicado 2021

NAD/NAMPT and mTOR Pathways in Melanoma: Drivers of Drug Resistance and Prospective Therapeutic Targets

por Indini, Alice, Fiorilla, Irene, Ponzone, Luca, Calautti, Enzo, Audrito, Valentina
Publicado 2022

NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer

por Audrito, Valentina, Managò, Antonella, Gaudino, Federica, Sorci, Leonardo, Messana, Vincenzo Gianluca, Raffaelli, Nadia, Deaglio, Silvia
Publicado 2019

Chronic Inflammation, Oxidative Stress and Metabolic Plasticity: Three Players Driving the Pro-Tumorigenic Microenvironment in Malignant Mesothelioma

por Fiorilla, Irene, Martinotti, Simona, Todesco, Alberto Maria, Bonsignore, Gregorio, Cavaletto, Maria, Patrone, Mauro, Ranzato, Elia, Audrito, Valentina
Publicado 2023

A Selective ALDH1A3 Inhibitor Impairs Mesothelioma 3-D Multicellular Spheroid Growth and Neutrophil Recruitment

por Boumya, Sara, Fallarini, Silvia, Siragusa, Sonia, Petrarolo, Giovanni, Aprile, Silvio, Audrito, Valentina, La Motta, Concettina, Garavaglia, Silvia, Moro, Laura, Pinton, Giulia
Publicado 2023

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4

por Gasparrini, Massimiliano, Mazzola, Francesca, Cuccioloni, Massimiliano, Sorci, Leonardo, Audrito, Valentina, Zamporlini, Federica, Fortunato, Carlo, Amici, Adolfo, Cianci, Michele, Deaglio, Silvia, Angeletti, Mauro, Raffaelli, Nadia
Publicado 2022

NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

por Audrito, Valentina, Messana, Vincenzo Gianluca, Moiso, Enrico, Vitale, Nicoletta, Arruga, Francesca, Brandimarte, Lorenzo, Gaudino, Federica, Pellegrino, Elisa, Vaisitti, Tiziana, Riganti, Chiara, Piva, Roberto, Deaglio, Silvia
Publicado 2020

Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia

por Fiorcari, Stefania, Maffei, Rossana, Audrito, Valentina, Martinelli, Silvia, Hacken, Elisa ten, Zucchini, Patrizia, Grisendi, Giulia, Potenza, Leonardo, Luppi, Mario, Burger, Jan A., Deaglio, Silvia, Marasca, Roberto
Publicado 2016

Targeting Mitochondria by SS-31 Ameliorates the Whole Body Energy Status in Cancer- and Chemotherapy-Induced Cachexia

por Ballarò, Riccardo, Lopalco, Patrizia, Audrito, Valentina, Beltrà, Marc, Pin, Fabrizio, Angelini, Roberto, Costelli, Paola, Corcelli, Angela, Bonetto, Andrea, Szeto, Hazel H., O’Connell, Thomas M., Penna, Fabio
Publicado 2021

miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression

por Quirico, Lorena, Orso, Francesca, Cucinelli, Stefania, Paradzik, Mladen, Natalini, Dora, Centonze, Giorgia, Dalmasso, Alberto, La Vecchia, Sofia, Coco, Martina, Audrito, Valentina, Riganti, Chiara, Defilippi, Paola, Taverna, Daniela
Publicado 2022

Tumors carrying BRAF-mutations over-express NAMPT that is genetically amplified and possesses oncogenic properties

por Audrito, Valentina, Moiso, Enrico, Ugolini, Filippo, Messana, Vincenzo Gianluca, Brandimarte, Lorenzo, Manfredonia, Ilaria, Bianchi, Simonetta, De Logu, Francesco, Nassini, Romina, Szumera-Ciećkiewicz, Anna, Taverna, Daniela, Massi, Daniela, Deaglio, Silvia
Publicado 2022

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma

por Audrito, Valentina, Managò, Antonella, Zamporlini, Federica, Rulli, Eliana, Gaudino, Federica, Madonna, Gabriele, D'Atri, Stefania, Antonini Cappellini, Gian Carlo, Ascierto, Paolo Antonio, Massi, Daniela, Raffaelli, Nadia, Mandalà, Mario, Deaglio, Silvia
Publicado 2018

Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer

por Lorenzato, Annalisa, Magrì, Alessandro, Matafora, Vittoria, Audrito, Valentina, Arcella, Pamela, Lazzari, Luca, Montone, Monica, Lamba, Simona, Deaglio, Silvia, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Bachi, Angela, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina
Publicado 2020

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p

por Audrito, Valentina, Serra, Sara, Stingi, Aureliano, Orso, Francesca, Gaudino, Federica, Bologna, Cinzia, Neri, Francesco, Garaffo, Giulia, Nassini, Romina, Baroni, Gianna, Rulli, Eliana, Massi, Daniela, Oliviero, Salvatore, Piva, Roberto, Taverna, Daniela, Mandalà, Mario, Deaglio, Silvia
Publicado 2017

Antagonists of growth hormone-releasing hormone (GHRH) inhibit the growth of human malignant pleural mesothelioma

por Villanova, Tania, Gesmundo, Iacopo, Audrito, Valentina, Vitale, Nicoletta, Silvagno, Francesca, Musuraca, Chiara, Righi, Luisella, Libener, Roberta, Riganti, Chiara, Bironzo, Paolo, Deaglio, Silvia, Papotti, Mauro, Cai, Renzhi, Sha, Wei, Ghigo, Ezio, Schally, Andrew V., Granata, Riccarda
Publicado 2019

Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation

por Managò, Antonella, Audrito, Valentina, Mazzola, Francesca, Sorci, Leonardo, Gaudino, Federica, Gizzi, Katiuscia, Vitale, Nicoletta, Incarnato, Danny, Minazzato, Gabriele, Ianniello, Alice, Varriale, Antonio, D’Auria, Sabato, Mengozzi, Giulio, Politano, Gianfranco, Oliviero, Salvatore, Raffaelli, Nadia, Deaglio, Silvia
Publicado 2019

Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death

por Salaro, Erica, Rambaldi, Alessia, Falzoni, Simonetta, Amoroso, Francesca Saveria, Franceschini, Alessia, Sarti, Alba Clara, Bonora, Massimo, Cavazzini, Francesco, Rigolin, Gian Matteo, Ciccone, Maria, Audrito, Valentina, Deaglio, Silvia, Pelegrin, Pablo, Pinton, Paolo, Cuneo, Antonio, Di Virgilio, Francesco
Publicado 2016