Rare variant association studies: considerations, challenges and opportunities

por Auer, Paul L, Lettre, Guillaume
Publicado 2015

Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci

por Rosse, Stephanie A, Auer, Paul L, Carlson, Christopher S
Publicado 2014

Regeneration Rosetta: An Interactive Web Application To Explore Regeneration-Associated Gene Expression and Chromatin Accessibility

por Rau, Andrea, Dhara, Sumona P., Udvadia, Ava J., Auer, Paul L.
Publicado 2019

Comparison of multiple imputation and other methods for the analysis of imputed genotypes

por Auer, Paul L., Wang, Gao, Li, Guangyou, DeWan, Andrew T., Leal, Suzanne M.
Publicado 2023

Individualized multi-omic pathway deviation scores using multiple factor analysis

por Rau, Andrea, Manansala, Regina, Flister, Michael J, Rui, Hallgeir, Jaffrézic, Florence, Laloë, Denis, Auer, Paul L
Publicado 2020

Prenatal Socioeconomic Disadvantage and Epigenetic Alterations at Birth Among Children Born to White British and Pakistani Mothers in the Born in Bradford Study

por Simanek, Amanda M., Manansala, Regina, Woo, Jennifer M.P., Meier, Helen C. S., Needham, Belinda L., Auer, Paul L.
Publicado 2022

Cellular reprogramming for successful CNS axon regeneration is driven by a temporally changing cast of transcription factors

por Dhara, Sumona P., Rau, Andrea, Flister, Michael J., Recka, Nicole M., Laiosa, Michael D., Auer, Paul L., Udvadia, Ava J.
Publicado 2019

A General Approach to Adjusting Genetic Studies for Assortative Mating

por Bilghese, Marta, Manansala, Regina, Jaishankar, Dhruva, Jala, Jonathan, Benjamin, Daniel J., Kimball, Miles, Auer, Paul L., Livermore, Michael A., Turley, Patrick
Publicado 2023

From GWAS variant to function: A study of ∼148,000 variants for blood cell traits

por Sun, Quan, Crowley, Cheynna A., Huang, Le, Wen, Jia, Chen, Jiawen, Bao, Erik L., Auer, Paul L., Lettre, Guillaume, Reiner, Alexander P., Sankaran, Vijay G., Raffield, Laura M., Li, Yun
Publicado 2021

Rare coding variants pinpoint genes that control human hematological traits

por Mousas, Abdou, Ntritsos, Georgios, Chen, Ming-Huei, Song, Ci, Huffman, Jennifer E., Tzoulaki, Ioanna, Elliott, Paul, Psaty, Bruce M., Auer, Paul L., Johnson, Andrew D., Evangelou, Evangelos, Lettre, Guillaume, Reiner, Alexander P.
Publicado 2017

Meta-Analysis of Gene Level Tests for Rare Variant Association

por Liu, Dajiang J., Peloso, Gina M., Zhan, Xiaowei, Holmen, Oddgeir L., Zawistowski, Matthew, Feng, Shuang, Nikpay, Majid, Auer, Paul L., Goel, Anuj, Zhang, He, Peters, Ulrike, Farrall, Martin, Orho-Melander, Marju, Kooperberg, Charles, McPherson, Ruth, Watkins, Hugh, Willer, Cristen J., Hveem, Kristian, Melander, Olle, Kathiresan, Sekar, Abecasis, Gonçalo R.
Publicado 2013

Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study

por Hu, Yao, Bien, Stephanie A., Nishimura, Katherine K., Haessler, Jeffrey, Hodonsky, Chani J., Baldassari, Antoine R., Highland, Heather M., Wang, Zhe, Preuss, Michael, Sitlani, Colleen M., Wojcik, Genevieve L., Tao, Ran, Graff, Mariaelisa, Huckins, Laura M., Sun, Quan, Chen, Ming-Huei, Mousas, Abdou, Auer, Paul L., Lettre, Guillaume, Kooperberg, Charles
Publicado 2021

Deleterious heteroplasmic mitochondrial mutations are associated with an increased risk of overall and cancer-specific mortality

por Hong, Yun Soo, Battle, Stephanie L., Shi, Wen, Puiu, Daniela, Pillalamarri, Vamsee, Xie, Jiaqi, Pankratz, Nathan, Lake, Nicole J., Lek, Monkol, Rotter, Jerome I., Rich, Stephen S., Kooperberg, Charles, Reiner, Alex P., Auer, Paul L., Heard-Costa, Nancy, Liu, Chunyu, Lai, Meng, Murabito, Joanne M., Levy, Daniel, Grove, Megan L., Alonso, Alvaro, Gibbs, Richard, Dugan-Perez, Shannon, Gondek, Lukasz P., Guallar, Eliseo, Arking, Dan E.
Publicado 2023

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

por Auer, Paul L., Teumer, Alexander, Schick, Ursula, O’Shaughnessy, Andrew, Lo, Ken Sin, Chami, Nathalie, Carlson, Chris, de Denus, Simon, Dubé, Marie-Pierre, Haessler, Jeff, Jackson, Rebecca D., Kooperberg, Charles, Perreault, Louis-Philippe Lemieux, Nauck, Matthias, Peters, Ulrike, Rioux, John D., Schmidt, Frank, Turcot, Valérie, Völker, Uwe, Völzke, Henry, Greinacher, Andreas, Hsu, Li, Tardif, Jean-Claude, Diaz, George A., Reiner, Alexander P., Lettre, Guillaume
Publicado 2014

TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data

por Huang, Le, Rosen, Jonathan D., Sun, Quan, Chen, Jiawen, Wheeler, Marsha M., Zhou, Ying, Min, Yuan-I, Kooperberg, Charles, Conomos, Matthew P., Stilp, Adrienne M., Rich, Stephen S., Rotter, Jerome I., Manichaikul, Ani, Loos, Ruth J.F., Kenny, Eimear E., Blackwell, Thomas W., Smith, Albert V., Jun, Goo, Sedlazeck, Fritz J., Metcalf, Ginger, Boerwinkle, Eric, Raffield, Laura M., Reiner, Alex P., Auer, Paul L., Li, Yun
Publicado 2022

Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease

por Raffield, Laura M., Ulirsch, Jacob C., Naik, Rakhi P., Lessard, Samuel, Handsaker, Robert E., Jain, Deepti, Kang, Hyun M., Pankratz, Nathan, Auer, Paul L., Bao, Erik L., Smith, Joshua D., Lange, Leslie A., Lange, Ethan M., Li, Yun, Thornton, Timothy A., Young, Bessie A., Abecasis, Goncalo R., Laurie, Cathy C., Nickerson, Deborah A., McCarroll, Steven A., Correa, Adolfo, Wilson, James G., Lettre, Guillaume, Sankaran, Vijay G., Reiner, Alex P.
Publicado 2018

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos

por Hodonsky, Chani J., Jain, Deepti, Schick, Ursula M., Morrison, Jean V., Brown, Lisa, McHugh, Caitlin P., Schurmann, Claudia, Chen, Diane D., Liu, Yong Mei, Auer, Paul L., Laurie, Cecilia A., Taylor, Kent D., Browning, Brian L., Li, Yun, Papanicolaou, George, Rotter, Jerome I., Kurita, Ryo, Nakamura, Yukio, Browning, Sharon R., Loos, Ruth J. F., North, Kari E., Laurie, Cathy C., Thornton, Timothy A., Pankratz, Nathan, Bauer, Daniel E., Sofer, Tamar, Reiner, Alex P.
Publicado 2017

Testing the role of predicted gene knockouts in human anthropometric trait variation

por Lessard, Samuel, Manning, Alisa K., Low-Kam, Cécile, Auer, Paul L., Giri, Ayush, Graff, Mariaelisa, Schurmann, Claudia, Yaghootkar, Hanieh, Luan, Jian'an, Esko, Tonu, Karaderi, Tugce, Bottinger, Erwin P., Lu, Yingchang, Carlson, Chris, Caulfield, Mark, Dubé, Marie-Pierre, Jackson, Rebecca D., Kooperberg, Charles, McKnight, Barbara, Mongrain, Ian, Peters, Ulrike, Reiner, Alex P., Rhainds, David, Sotoodehnia, Nona, Hirschhorn, Joel N., Scott, Robert A., Munroe, Patricia B., Frayling, Timothy M., Loos, Ruth J.F., North, Kari E., Edwards, Todd L., Tardif, Jean-Claude, Lindgren, Cecilia M., Lettre, Guillaume
Publicado 2016

Correction to: Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) Study

por Hu, Yao, Bien, Stephanie A., Nishimura, Katherine K., Haessler, Jeffrey, Hodonsky, Chani J., Baldassari, Antoine R., Highland, Heather M., Wang, Zhe, Preuss, Michael, Sitlani, Colleen M., Wojcik, Genevieve L., Tao, Ran, Graff, Mariaelisa, Huckins, Laura M., Sun, Quan, Chen, Ming-Huei, Mousas, Abdou, Auer, Paul L., Lettre, Guillaume, Tang, Weihong, Qi, Lihong, Thyagarajan, Bharat, Buyske, Steve, Fornage, Myriam, Hindorff, Lucia A., Li, Yun, Lin, Danyu, Reiner, Alexander P., North, Kari E., Loos, Ruth J. F., Raffield, Laura M., Peters, Ulrike, Avery, Christy L., Kooperberg, Charles
Publicado 2021

Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data

por Bien, Stephanie A., Auer, Paul L., Harrison, Tabitha A., Qu, Conghui, Connolly, Charles M., Greenside, Peyton G., Chen, Sai, Berndt, Sonja I., Bézieau, Stéphane, Kang, Hyun M., Huyghe, Jeroen, Brenner, Hermann, Casey, Graham, Chan, Andrew T., Hopper, John L., Banbury, Barbara L., Chang-Claude, Jenny, Chanock, Stephen J., Haile, Robert W., Hoffmeister, Michael, Fuchsberger, Christian, Jenkins, Mark A., Leal, Suzanne M., Lemire, Mathieu, Newcomb, Polly A., Gallinger, Steven, Potter, John D., Schoen, Robert E., Slattery, Martha L., Smith, Joshua D., Le Marchand, Loic, White, Emily, Zanke, Brent W., Abeçasis, Goncalo R., Carlson, Christopher S., Peters, Ulrike, Nickerson, Deborah A., Kundaje, Anshul, Hsu, Li
Publicado 2017