Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia

por Aulin, Linda B. S., Kleijburg, Anne, Moerland, Matthijs, van Hasselt, J. G. Coen
Publicado 2022

Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism

por Liu, Feiyan, Aulin, Linda B. S., Manson, Martijn L., Krekels, Elke H. J., van Hasselt, J. G. Coen
Publicado 2023

Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution

por Liakopoulos, Apostolos, Aulin, Linda B. S., Buffoni, Matteo, Fragkiskou, Efthymia, Coen van Hasselt, J. G., Rozen, Daniel E.
Publicado 2022

Design principles of collateral sensitivity-based dosing strategies

por Aulin, Linda B. S., Liakopoulos, Apostolos, van der Graaf, Piet H., Rozen, Daniel E., van Hasselt, J. G. Coen
Publicado 2021

Evaluating the prevalence of Hepatitis E virus infection in a large cohort of European blood donors, 2015–2018

por Healy, Katie, Freij, Urban, Ellerstad, Marie, Aulin, Linda B. S., Brückle, Lena, Hillmering, Helen, Chen, Margaret Sällberg, Gustafsson, Rasmus
Publicado 2022

Prevalence of Parvovirus B19 Viremia Among German Blood Donations and the Relationship to ABO and Rhesus Blood Group Antigens

por Healy, Katie, Aulin, Linda B S, Freij, Urban, Ellerstad, Marie, Brückle, Lena, Hillmering, Helen, Svae, Tor-Einar, Broliden, Kristina, Gustafsson, Rasmus
Publicado 2022

Biomarker‐Guided Individualization of Antibiotic Therapy

por Aulin, Linda B.S., de Lange, Dylan W., Saleh, Mohammed A.A., van der Graaf, Piet H., Völler, Swantje, van Hasselt, J.G. Coen
Publicado 2021

Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations

por Liu, Feiyan, Aulin, Linda B. S., Guo, Tingjie, Krekels, Elke H. J., Moerland, Matthijs, van der Graaf, Piet H., van Hasselt, Johan G. C.
Publicado 2022

Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review

por Démaris, Alix, Widigson, Ella S. K., Ilvemark, Johan F. K. F., Steenholdt, Casper, Seidelin, Jakob B., Huisinga, Wilhelm, Michelet, Robin, Aulin, Linda B. S., Kloft, Charlotte
Publicado 2022

Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans

por Aulin, Linda B. S., Valitalo, Pyry A., Rizk, Matthew L., Visser, Sandra A. G., Rao, Gauri, van der Graaf, Piet H., van Hasselt, J. G. Coen
Publicado 2018

A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis

por Liu, Feiyan, Aulin, Linda B. S., Kossen, Sebastiaan S. A., Cathalina, Julius, Bremmer, Marlotte, Foks, Amanda C., van der Graaf, Piet H., Moerland, Matthijs, van Hasselt, Johan G. C.
Publicado 2022

Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations

por Aulin, Linda B. S., Tandar, Sebastian T., van Zijp, Torben, van Ballegooie, Etienne, van der Graaf, Piet H., Saleh, Mohammed A. A., Välitalo, Pyry, van Hasselt, J. G. Coen
Publicado 2022

Barriers to global pharmacometrics: educational challenges and opportunities across the globe

por Michelet, Robin, Aulin, Linda B. S., Borghardt, Jens M., Costa, Teresa Dalla, Denti, Paolo, Ibarra, Manuel, Ma, Guangda, Meibohm, Bernd, Pillai, Goonaseelan (Colin), Schmidt, Stephan, Hennig, Stefanie, Kloft, Charlotte
Publicado 2023