Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis

por Lachén-Montes, Mercedes, Mendizuri, Naroa, Ausin, Karina, Andrés-Benito, Pol, Ferrer, Isidro, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2020

Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease

por Ferrer, Isidro, Andrés‐Benito, Pol, Ausín, Karina, Pamplona, Reinald, del Rio, José Antonio, Fernández‐Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2021

Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer’s Disease Mouse Model

por Palomino-Alonso, Maialen, Lachén-Montes, Mercedes, González-Morales, Andrea, Ausín, Karina, Pérez-Mediavilla, Alberto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2017

Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression

por Lachén-Montes, Mercedes, González-Morales, Andrea, Zelaya, María Victoria, Pérez-Valderrama, Estela, Ausín, Karina, Ferrer, Isidro, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2017

Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

por Iridoy, Marina Oaia, Zubiri, Irene, Zelaya, María Victoria, Martinez, Leyre, Ausín, Karina, Lachen-Montes, Mercedes, Santamaría, Enrique, Fernandez-Irigoyen, Joaquín, Jericó, Ivonne
Publicado 2018

Dysregulated Brain Protein Phosphorylation Linked to Increased Human Tau Expression in the hTau Transgenic Mouse Model

por Ferrer, Isidro, Andrés-Benito, Pol, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2022

Metabolic dyshomeostasis induced by SARS-CoV-2 structural proteins reveals immunological insights into viral olfactory interactions

por Lachén-Montes, Mercedes, Mendizuri, Naroa, Ausín, Karina, Echaide, Miriam, Blanco, Ester, Chocarro, Luisa, de Toro, María, Escors, David, Fernández-Irigoyen, Joaquín, Kochan, Grazyna, Santamaría, Enrique
Publicado 2022

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease

por Lachen-Montes, Mercedes, González-Morales, Andrea, Palomino, Maialen, Ausin, Karina, Gómez-Ochoa, Marta, Zelaya, María Victoria, Ferrer, Isidro, Pérez-Mediavilla, Alberto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Publicado 2019

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy

por Ferrer, Isidro, Andrés-Benito, Pol, Zelaya, Maria Victoria, Aguirre, Maria Elena Erro, Carmona, Margarita, Ausín, Karina, Lachén-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, del Rio, José Antonio
Publicado 2020

Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse

por Andrés-Benito, Pol, Flores, África, Busquet-Areny, Sara, Carmona, Margarita, Ausín, Karina, Cartas-Cejudo, Paz, Lachén-Montes, Mercedes, Del Rio, José Antonio, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Ferrer, Isidro
Publicado 2023

Cannabis Use Induces Distinctive Proteomic Alterations in Olfactory Neuroepithelial Cells of Schizophrenia Patients

por Barrera-Conde, Marta, Ausin, Karina, Lachén-Montes, Mercedes, Fernández-Irigoyen, Joaquín, Galindo, Liliana, Cuenca-Royo, Aida, Fernández-Avilés, Cristina, Pérez, Víctor, de la Torre, Rafael, Santamaría, Enrique, Robledo, Patricia
Publicado 2021

Absence of Nuclear p16 Is a Diagnostic and Independent Prognostic Biomarker in Squamous Cell Carcinoma of the Cervix

por Mendaza, Saioa, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Zudaire, Tamara, Guarch, Rosa, Guerrero-Setas, David, Vidal, August, Santos-Salas, José, Matias-Guiu, Xavier, Ausín, Karina, Díaz de Cerio, María José, Martín-Sánchez, Esperanza
Publicado 2020

Brain IGF-I regulates LTP, spatial memory, and sexual dimorphic behavior

por Herrero-Labrador, Raquel, Fernández-Irigoyen, Joaquín, Vecino, Rebeca, González-Arias, Candela, Ausín, Karina, Crespo, Inmaculada, Fernández Acosta, Francisco J, Nieto-Estévez, Vanesa, Román, M José, Perea, Gertrudis, Torres-Alemán, Ignacio, Santamaría, Enrique, Vicario, Carlos
Publicado 2023

Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition

por Arasanz, Hugo, Hernández, Carlos, Bocanegra, Ana, Chocarro, Luisa, Zuazo, Miren, Gato, Maria, Ausin, Karina, Santamaría, Enrique, Fernández-Irigoyen, Joaquín, Fernandez, Gonzalo, Santamaria, Eva, Rodríguez, Carlos, Blanco-Luquin, Idoia, Vera, Ruth, Escors, David, Kochan, Grazyna
Publicado 2020

Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix

por Mendaza, Saioa, Fernández-Irigoyen, Joaquín, Santamaría, Enrique, Arozarena, Imanol, Guerrero-Setas, David, Zudaire, Tamara, Guarch, Rosa, Vidal, August, Salas, José-Santos, Matias-Guiu, Xavier, Ausín, Karina, Gil, Carmen, Hernández-Alcoceba, Rubén, Martín-Sánchez, Esperanza
Publicado 2021

Mass Spectrometry-Based Proteomic Profiling of Thrombotic Material Obtained by Endovascular Thrombectomy in Patients with Ischemic Stroke

por Muñoz, Roberto, Santamaría, Enrique, Rubio, Idoya, Ausín, Karina, Ostolaza, Aiora, Labarga, Alberto, Roldán, Miren, Zandio, Beatriz, Mayor, Sergio, Bermejo, Rebeca, Mendigaña, Mónica, Herrera, María, Aymerich, Nuria, Olier, Jorge, Gállego, Jaime, Mendioroz, Maite, Fernández-Irigoyen, Joaquín
Publicado 2018

Circulating Low Density Neutrophils Are Associated with Resistance to First Line Anti-PD1/PDL1 Immunotherapy in Non-Small Cell Lung Cancer

por Arasanz, Hugo, Bocanegra, Ana Isabel, Morilla, Idoia, Fernández-Irigoyen, Joaquín, Martínez-Aguillo, Maite, Teijeira, Lucía, Garnica, Maider, Blanco, Ester, Chocarro, Luisa, Ausin, Karina, Zuazo, Miren, Fernández-Hinojal, Gonzalo, Echaide, Miriam, Fernández-Rubio, Leticia, Piñeiro-Hermida, Sergio, Ramos, Pablo, Mezquita, Laura, Escors, David, Vera, Ruth, Kochan, Grazyna
Publicado 2022

A Proteomic Atlas of Lineage and Cancer-Polarized Expression Modules in Myeloid Cells Modeling Immunosuppressive Tumor-Infiltrating Subsets

por Blanco, Ester, Ibañez-Vea, Maria, Hernandez, Carlos, Drici, Lylia, Martínez de Morentin, Xabier, Gato, Maria, Ausin, Karina, Bocanegra, Ana, Zuazo, Miren, Chocarro, Luisa, Arasanz, Hugo, Fernandez-Hinojal, Gonzalo, Fernandez-Irigoyen, Joaquin, Smerdou, Cristian, Garnica, Maider, Echaide, Miriam, Fernandez, Leticia, Morente, Pilar, Ramos-Castellanos, Pablo, Llopiz, Diana, Santamaria, Enrique, Larsen, Martin R., Escors, David, Kochan, Grazyna
Publicado 2021