Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies

por Gros, Christina, Chauvigné, Laura, Poulet, Anaïs, Menon, Yoann, Ausseil, Frédéric, Dufau, Isabelle, Arimondo, Paola B.
Publicado 2013

Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

por Dufau, Isabelle, Frongia, Céline, Sicard, Flavie, Dedieu, Laure, Cordelier, Pierre, Ausseil, Frédéric, Ducommun, Bernard, Valette, Annie
Publicado 2012

Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells

por Gregoire, Jean-Marc, Fleury, Laurence, Salazar-Cardozo, Clara, Alby, Frédéric, Masson, Véronique, Arimondo, Paola Barbara, Ausseil, Frédéric
Publicado 2016

New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors

por Gros, Christina, Fleury, Laurence, Nahoum, Virginie, Faux, Céline, Valente, Sergio, Labella, Donatella, Cantagrel, Frédéric, Rilova, Elodie, Bouhlel, Mohamed Amine, David-Cordonnier, Marie-Hélène, Dufau, Isabelle, Ausseil, Frédéric, Mai, Antonello, Mourey, Lionel, Lacroix, Laurent, Arimondo, Paola B.
Publicado 2015

Design, Synthesis and Biological Evaluation of 4-Amino-N-(4-aminophenyl)benzamide Analogues of Quinoline-Based SGI-1027 as Inhibitors of DNA Methylation

por Rilova, Elodie, Erdmann, Alexandre, Gros, Christina, Masson, Véronique, Aussagues, Yannick, Poughon-Cassabois, Valérie, Rajavelu, Arumugam, Jeltsch, Albert, Menon, Yoann, Novosad, Natacha, Gregoire, Jean-Marc, Vispé, Stéphane, Schambel, Philippe, Ausseil, Fréderic, Sautel, François, Arimondo, Paola B, Cantagrel, Frédéric
Publicado 2014

Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity

por Rotili, Dante, Tarantino, Domenico, Marrocco, Biagina, Gros, Christina, Masson, Véronique, Poughon, Valérie, Ausseil, Fréderic, Chang, Yanqi, Labella, Donatella, Cosconati, Sandro, Di Maro, Salvatore, Novellino, Ettore, Schnekenburger, Michael, Grandjenette, Cindy, Bouvy, Celine, Diederich, Marc, Cheng, Xiaodong, Arimondo, Paola B., Mai, Antonello
Publicado 2014

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

por Zwergel, Clemens, Schnekenburger, Michael, Sarno, Federica, Battistelli, Cecilia, Manara, Maria Cristina, Stazi, Giulia, Mazzone, Roberta, Fioravanti, Rossella, Gros, Christina, Ausseil, Frédéric, Florean, Cristina, Nebbioso, Angela, Strippoli, Raffaele, Ushijima, Toshikazu, Scotlandi, Katia, Tripodi, Marco, Arimondo, Paola B., Altucci, Lucia, Diederich, Marc, Mai, Antonello, Valente, Sergio
Publicado 2019

Correction: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

por Zwergel, Clemens, Schnekenburger, Michael, Sarno, Federica, Battistelli, Cecilia, Manara, Maria Cristina, Stazi, Giulia, Mazzone, Roberta, Fioravanti, Rossella, Gros, Christina, Ausseil, Frédéric, Florean, Cristina, Nebbioso, Angela, Strippoli, Raffaele, Ushijima, Toshikazu, Scotlandi, Katia, Tripodi, Marco, Arimondo, Paola B., Altucci, Lucia, Diederich, Marc, Mai, Antonello, Valente, Sergio
Publicado 2022