Sequence-based prediction of pH-dependent protein solubility using CamSol

por Oeller, Marc, Kang, Ryan, Bell, Rosie, Ausserwöger, Hannes, Sormanni, Pietro, Vendruscolo, Michele
Publicado 2023

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

por Kar, Mrityunjoy, Vogel, Laura T., Chauhan, Gaurav, Ausserwöger, Hannes, Welsh, Timothy J., Kamath, Anjana R., Knowles, Tuomas P. J., Hyman, Anthony A., Seidel, Claus A. M., Pappu, Rohit V.
Publicado 2023

Spatially non-uniform condensates emerge from dynamically arrested phase separation

por Erkamp, Nadia A., Sneideris, Tomas, Ausserwöger, Hannes, Qian, Daoyuan, Qamar, Seema, Nixon-Abell, Jonathon, St George-Hyslop, Peter, Schmit, Jeremy D., Weitz, David A., Knowles, Tuomas P. J.
Publicado 2023

Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform

por Erkamp, Nadia A., Oeller, Marc, Sneideris, Tomas, Ausserwoger, Hannes, Levin, Aviad, Welsh, Timothy J., Qi, Runzhang, Qian, Daoyuan, Lorenzen, Nikolai, Zhu, Hongjia, Sormanni, Pietro, Vendruscolo, Michele, Knowles, Tuomas P.J.
Publicado 2023

Surface patches induce nonspecific binding and phase separation of antibodies

por Ausserwöger, Hannes, Krainer, Georg, Welsh, Timothy J., Thorsteinson, Nels, de Csilléry, Ella, Sneideris, Tomas, Schneider, Matthias M., Egebjerg, Thomas, Invernizzi, Gaetano, Herling, Therese W., Lorenzen, Nikolai, Knowles, Tuomas P. J.
Publicado 2023

Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides

por Sneideris, Tomas, Erkamp, Nadia A., Ausserwöger, Hannes, Saar, Kadi L., Welsh, Timothy J., Qian, Daoyuan, Katsuya-Gaviria, Kai, Johncock, Margaret L. L. Y., Krainer, Georg, Borodavka, Alexander, Knowles, Tuomas P. J.
Publicado 2023