Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells

por Bakke, Jesse, Wright, William C., Zamora, Anthony E., Oladimeji, Peter, Crawford, Jeremy Chase, Brewer, Christopher T., Autry, Robert J., Evans, William E., Thomas, Paul G., Chen, Taosheng
Publicado 2019

miR-331-3p is involved in glucocorticoid resistance reversion by rapamycin through suppression of the MAPK signaling pathway

por Lucafò, Marianna, Sicari, Daria, Chicco, Andrea, Curci, Debora, Bellazzo, Arianna, Di Silvestre, Alessia, Pegolo, Chiara, Autry, Robert, Cecchin, Erika, De Iudicibus, Sara, Collavin, Licio, Evans, William, Decorti, Giuliana, Stocco, Gabriele
Publicado 2020

Simultaneous monitoring of disease and microbe dynamics through plasma DNA sequencing in pediatric patients with acute lymphoblastic leukemia

por Barsan, Valentin, Xia, Yuntao, Klein, David, Gonzalez-Pena, Veronica, Youssef, Sarah, Inaba, Yuki, Mahmud, Ousman, Natarajan, Sivaraman, Agarwal, Vibhu, Pang, Yakun, Autry, Robert, Pui, Ching-Hon, Inaba, Hiroto, Evans, William, Gawad, Charles
Publicado 2022

Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers

por Thatikonda, Venu, Islam, S. M. Ashiqul, Autry, Robert J., Jones, Barbara C., Gröbner, Susanne N., Warsow, Gregor, Hutter, Barbara, Huebschmann, Daniel, Fröhling, Stefan, Kool, Marcel, Blattner-Johnson, Mirjam, Jones, David T. W., Alexandrov, Ludmil B., Pfister, Stefan M., Jäger, Natalie
Publicado 2023

Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia

por Bergeron, Brennan P., Diedrich, Jonathan D., Zhang, Yang, Barnett, Kelly R., Dong, Qian, Ferguson, Daniel C., Autry, Robert J., Yang, Wenjian, Hansen, Baranda S., Smith, Colton, Crews, Kristine R., Fan, Yiping, Pui, Ching-Hon, Pruett-Miller, Shondra M., Relling, Mary V., Yang, Jun J., Li, Chunliang, Evans, William E., Savic, Daniel
Publicado 2022

Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia

por Karol, Seth E., Larsen, Eric, Cheng, Cheng, Cao, Xueyuan, Yang, Wenjian, Ramsey, Laura B., Fernandez, Christian A., McCorkle, Joseph R., Paugh, Steven W., Autry, Robert J., Lopez-Lopez, Elixabet, Diouf, Barthelemy, Jeha, Sima, Pui, Ching-Hon, Raetz, Elizabeth A., Winick, Naomi J., Carroll, William L., Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi, Evans, William E., Yang, Jun J., Relling, Mary V.
Publicado 2017

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

por Diouf, Barthelemy, Wing, Claudia, Panetta, John C., Eddins, Donnie, Lin, Wenwei, Yang, Wenjian, Fan, Yiping, Pei, Deqing, Cheng, Cheng, Delaney, Shannon M., Zhang, Wei, Bonten, Erik J., Crews, Kristine R., Paugh, Steven W., Li, Lie, Freeman, Burgess B., Autry, Robert J., Beard, Jordan A., Ferguson, Daniel C., Janke, Laura J., Ness, Kirsten K., Chen, Taosheng, Zakharenko, Stanislav S., Jeha, Sima, Pui, Ching‐Hon, Relling, Mary V., Eileen Dolan, M., Evans, William E.
Publicado 2021

Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma

por Schedel, Anne, Friedrich, Ulrike Anne, Morcos, Mina N. F., Wagener, Rabea, Mehtonen, Juha, Watrin, Titus, Saitta, Claudia, Brozou, Triantafyllia, Michler, Pia, Walter, Carolin, Försti, Asta, Baksi, Arka, Menzel, Maria, Horak, Peter, Paramasivam, Nagarajan, Fazio, Grazia, Autry, Robert J, Fröhling, Stefan, Suttorp, Meinolf, Gertzen, Christoph, Gohlke, Holger, Bhatia, Sanil, Wadt, Karin, Schmiegelow, Kjeld, Dugas, Martin, Richter, Daniela, Glimm, Hanno, Heinäniemi, Merja, Jessberger, Rolf, Cazzaniga, Gianni, Borkhardt, Arndt, Hauer, Julia, Auer, Franziska
Publicado 2022

Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia

por Ferguson, Daniel C., McCorkle, J. Robert, Barnett, Kelly R., Bonten, Erik J., Bergeron, Brennan P., Bhattarai, Kashi Raj, Yang, Wenjian, Smith, Colton, Hansen, Baranda S., Bajpai, Richa, Dong, Qian, Autry, Robert J., Gocho, Yoshihiro, Diedrich, Jonathan D., Crews, Kristine R., Pruett-Miller, Shondra M., Roberts, Kathryn G., Stock, Wendy, Mullighan, Charles G., Inaba, Hiroto, Jeha, Sima, Pui, Ching-Hon, Yang, Jun J., Relling, Mary V., Evans, William E., Savic, Daniel
Publicado 2022

Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication

por Liu, Yanling, Klein, Jonathon, Bajpai, Richa, Dong, Li, Tran, Quang, Kolekar, Pandurang, Smith, Jenny L., Ries, Rhonda E., Huang, Benjamin J., Wang, Yi-Cheng, Alonzo, Todd A., Tian, Liqing, Mulder, Heather L., Shaw, Timothy I., Ma, Jing, Walsh, Michael P., Song, Guangchun, Westover, Tamara, Autry, Robert J., Gout, Alexander M., Wheeler, David A., Wan, Shibiao, Wu, Gang, Yang, Jun J., Evans, William E., Loh, Mignon, Easton, John, Zhang, Jinghui, Klco, Jeffery M., Meshinchi, Soheil, Brown, Patrick A., Pruett-Miller, Shondra M., Ma, Xiaotu
Publicado 2023

MDB-15. CLINICAL CHARACTERISTICS AND OUTCOME OF CHILDHOOD LI-FRAUMENI SYNDROME MEDULLOBLASTOMA PATIENTS

por Kolodziejczak, Anna, Guerrini-Rousseau, Lea, Planchon, Julien Masliah, Mynarek, Martin, Sill, Martin, Autry, Robert, Zhao, Eric, Hirsch, Steffen, Dufour, Christelle, Ayrault, Olivier, Waszak, Sebastian, Ramaswamy, Vijay, Pentikainen, Virve, Clifford, Steven, Schwalbe, Ed, Massimi, Luca, Snuderl, Matija, Karajannis, Matthias, White, Christine, Redmond, Shelagh, Loizos, Loizou, Jakob, Marcus, Schmid, Irene, Hauer, Julia, Blattmann, Claudia, Filippidou, Maria, Sutter, Christian, Pietsch, Torsten, Frank, Stephan, Schewe, Denis, Malkin, David, Sehested, Astrid, Wong, Tai-Tong, Carceller, Fernando, Mueller, Sabine, Taylor, Michael, Tabori, Uri, Bouffet, Eric, Kool, Marcel, Sahm, Felix, Kratz, Christian, Sturm, Dominik, Jones, David, Rutkowski, Stefan, Witt, Olaf, Bougeard, Gaëlle, Pajtler, Kristian, Pfister, Stefan, Bourdeaut, Franck, Milde, Till
Publicado 2023