682. In Vivo Pharmacodynamics of VNRX-7145 in the Neutropenic Murine Thigh Infection Model When Administered in Combination with Humanized Exposures of Twice Daily Ceftibuten (CTB)...

por Avery, Lindsay M, Abdelraouf, Kamilia, Nicolau, David P
Publicado 2019

685. An In Vitro Investigation of WCK 5222 (Cefepime/Zidebactam) and Currently Available Combination Antibiotic Regimens Against Enterobacteriaceae That Co-express Serine-β-Lactama...

por Avery, Lindsay M, Mullane, Elias M, Nicolau, David P
Publicado 2019

725. WCK 5222 (Cefepime/Zidebactam): An In Vitro Assessment of Activity Compared with Current Dual-Antibiotic Options Against Multidrug-Resistant Pseudomonas aeruginosa

por Mullane, Elias M, Avery, Lindsay M, Nicolau, David P
Publicado 2019

1336. Assessment of the In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) Against Carbapenems-Resistant Acinetobacter baumannii (CR-ACBN) in the Neutropenic Murine Thigh Infection...

por Abuhussain, Safa Almarzoky, Avery, Lindsay, Abdelraouf, Kamilia, Nicolau, David P
Publicado 2018

1263. Assessment of Cefepime (FEP)-Taniborbactam (TAN) Human Exposures to Suppress the Emergence of Resistance among Serine (SBL)- and Metallo-β-Lactamase (MBL)-Producing Gram-Nega...

por Avery, Lindsay M, Vernacchio, Salvador, McLaughlin, Lisa, Xerri, Luigi, Moeck, Greg, Pevear, Daniel
Publicado 2020

Linear pharmacokinetic parameters for monoclonal antibodies are similar within a species and across different pharmacological targets: A comparison between human, cynomolgus monkey...

por Betts, Alison, Keunecke, Anne, van Steeg, Tamara J., van der Graaf, Piet H., Avery, Lindsay B., Jones, Hannah, Berkhout, Jan
Publicado 2018

Changes in complementarity-determining regions significantly alter IgG binding to the neonatal Fc receptor (FcRn) and pharmacokinetics

por Piche-Nicholas, Nicole M., Avery, Lindsay B., King, Amy C., Kavosi, Mania, Wang, Mengmeng, O'Hara, Denise M., Tchistiakova, Lioudmila, Katragadda, Madan
Publicado 2017

A Physiologically‐Based Pharmacokinetic Model for the Prediction of Monoclonal Antibody Pharmacokinetics From In Vitro Data

por Jones, Hannah M., Zhang, Zhiwei, Jasper, Paul, Luo, Haobin, Avery, Lindsay B., King, Lindsay E., Neubert, Hendrik, Barton, Hugh A., Betts, Alison M., Webster, Robert
Publicado 2019

Neuroprotective maraviroc monotherapy in simian immunodeficiency virus-infected macaques: reduced replicating and latent SIV in the brain

por Kelly, Kathleen M., Beck, Sarah E., Pate, Kelly A. Metcalf, Queen, Suzanne E., Dorsey, Jamie L., Adams, Robert J., Avery, Lindsay B., Hubbard, Walter, Tarwater, Patrick M., Mankowski, Joseph L.
Publicado 2013

1643. Pharmacodynamics (PD) of Daptomycin (DAP) in Combination Therapy for Enterococcal Bloodstream Infection (BSI)

por Avery, Lindsay, Kuti, Joseph L, Weisser, Maja, Egli, Adrian, Rybak, Michael J, Zasowski, Evan J, Arias, Cesar, Contreras, German, Chong, Pearlie, Aitken, Samuel L, DiPippo, Adam J, Wang, Jann-Tay, Britt, Nicholas S, Nicolau, David P
Publicado 2018

A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1

por Prusevich, Polina, Kalin, Jay H., Ming, Shonoi A., Basso, Manuela, Givens, Jeffrey, Li, Xin, Hu, Jianfei, Taylor, Martin S., Cieniewicz, Anne M., Hsiao, Po-Yuan, Huang, Rong, Roberson, Heather, Adejola, Nkosi, Avery, Lindsay B., Casero, Robert A., Taverna, Sean D., Qian, Jiang, Tackett, Alan J., Ratan, Rajiv R., McDonald, Oliver G., Feinberg, Andrew P., Cole, Philip A.
Publicado 2014