CureHeart wins Big Beat Challenge, a £30 million research award from the British Heart Foundation( )

por Avkiran, Metin
Publicado 2022

Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms

por Weeks, Kate L, Avkiran, Metin
Publicado 2015

Regulation by phosphodiesterase isoforms of protein kinase A-mediated attenuation of myocardial protein kinase D activation

por Haworth, Robert S., Cuello, Friederike, Avkiran, Metin
Publicado 2010

β-Adrenergic regulation of cardiac type 2A protein phosphatase through phosphorylation of regulatory subunit B56δ at S573

por Ranieri, Antonella, Kemp, Elizabeth, Burgoyne, Joseph R., Avkiran, Metin
Publicado 2018

Phosphorylation at Serines 157 and 161 Is Necessary for Preserving Cardiac Expression Level and Functions of Sarcomeric Z-Disc Protein Telethonin

por Lewis, Hannah R., Eminaga, Seda, Gautel, Mathias, Avkiran, Metin
Publicado 2021

Regulation of PP2A(C) Carboxylmethylation and Cellular Localisation by Inhibitory Class G-Protein Coupled Receptors in Cardiomyocytes

por Longman, Michael R., Ranieri, Antonella, Avkiran, Metin, Snabaitis, Andrew K.
Publicado 2014

Assessing structural and functional responses of murine hearts to acute and sustained β-adrenergic stimulation in vivo

por Puhl, Sarah-Lena, Weeks, Kate L., Ranieri, Antonella, Avkiran, Metin
Publicado 2016

Quantitative Analysis of the Cardiac Phosphoproteome in Response to Acute β-Adrenergic Receptor Stimulation In Vivo

por Güran, Alican, Ji, Yanlong, Fang, Pan, Pan, Kuan-Ting, Urlaub, Henning, Avkiran, Metin, Lenz, Christof
Publicado 2021

Proteomics Analysis of the Cardiac Myofilament Subproteome Reveals Dynamic Alterations in Phosphatase Subunit Distribution

por Yin, Xiaoke, Cuello, Friederike, Mayr, Ursula, Hao, Zhiqi, Hornshaw, Martin, Ehler, Elisabeth, Avkiran, Metin, Mayr, Manuel
Publicado 2010

Four-and-a-half LIM domains proteins are novel regulators of the protein kinase D pathway in cardiac myocytes

por Stathopoulou, Konstantina, Cuello, Friederike, Candasamy, Alexandra J., Kemp, Elizabeth M., Ehler, Elisabeth, Haworth, Robert S., Avkiran, Metin
Publicado 2014

Role of type 2A phosphatase regulatory subunit B56α in regulating cardiac responses to β-adrenergic stimulation in vivo

por Puhl, Sarah-Lena, Weeks, Kate L, Güran, Alican, Ranieri, Antonella, Boknik, Peter, Kirchhefer, Uwe, Müller, Frank U, Avkiran, Metin
Publicado 2019

β‐Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α‐PP2A‐Mediated Dephosphorylation

por Weeks, Kate L., Ranieri, Antonella, Karaś, Agnieszka, Bernardo, Bianca C., Ashcroft, Alexandra S., Molenaar, Chris, McMullen, Julie R., Avkiran, Metin
Publicado 2017

Phosphoregulation of the Titin-cap Protein Telethonin in Cardiac Myocytes

por Candasamy, Alexandra J., Haworth, Robert S., Cuello, Friederike, Ibrahim, Michael, Aravamudhan, Sriram, Krüger, Marcus, Holt, Mark R., Terracciano, Cesare M. N., Mayr, Manuel, Gautel, Mathias, Avkiran, Metin
Publicado 2014

Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca(2+) sensitivity and calpain-induced proteolysis

por Martin-Garrido, Abel, Biesiadecki, Brandon J., Salhi, Hussam E., Shaifta, Yasin, dos Remedios, Cristobal G., Ayaz-Guner, Serife, Cai, Wenxuan, Ge, Ying, Avkiran, Metin, Kentish, Jonathan C.
Publicado 2018

Increased myofilament Ca(2+) sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice

por Fraysse, Bodvaël, Weinberger, Florian, Bardswell, Sonya C., Cuello, Friederike, Vignier, Nicolas, Geertz, Birgit, Starbatty, Jutta, Krämer, Elisabeth, Coirault, Catherine, Eschenhagen, Thomas, Kentish, Jonathan C., Avkiran, Metin, Carrier, Lucie
Publicado 2012

Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy

por Hoskins, Anita C., Jacques, Adam, Bardswell, Sonya C., McKenna, William J., Tsang, Victor, dos Remedios, Cristobal G., Ehler, Elisabeth, Adams, Kim, Jalilzadeh, Shapour, Avkiran, Metin, Watkins, Hugh, Redwood, Charles, Marston, Steven B., Kentish, Jonathan C.
Publicado 2010

Inflammation leads through PGE/EP (3) signaling to HDAC5/MEF2‐dependent transcription in cardiac myocytes

por Tóth, András D, Schell, Richard, Lévay, Magdolna, Vettel, Christiane, Theis, Philipp, Haslinger, Clemens, Alban, Felix, Werhahn, Stefanie, Frischbier, Lina, Krebs‐Haupenthal, Jutta, Thomas, Dominique, Gröne, Hermann‐Josef, Avkiran, Metin, Katus, Hugo A, Wieland, Thomas, Backs, Johannes
Publicado 2018