Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

por Stockton, Rebecca A., Shenkar, Robert, Awad, Issam A., Ginsberg, Mark H.
Publicado 2010

Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation

por Wei, Shu, Li, Ye, Polster, Sean P., Weber, Christopher R., Awad, Issam A., Shen, Le
Publicado 2020

Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations

por Li, Wenqing, Tran, Virginia, Shaked, Iftach, Xue, Belinda, Moore, Thomas, Lightle, Rhonda, Kleinfeld, David, Awad, Issam A, Ginsberg, Mark H
Publicado 2021

Single-nucleus DNA sequencing reveals hidden somatic loss-of-heterozygosity in Cerebral Cavernous Malformations

por Ressler, Andrew K., Snellings, Daniel A., Girard, Romuald, Gallione, Carol J., Lightle, Rhonda, Allen, Andrew S., Awad, Issam A., Marchuk, Douglas A.
Publicado 2023

COVID-19 in a Hemorrhagic Neurovascular Disease, Cerebral Cavernous Malformation

por Shkoukani, Abdallah, Srinath, Abhinav, Stadnik, Agnieszka, Girard, Romuald, Shenkar, Robert, Sheline, Adrienne, Dahlem, Kristen, Lee, Cornelia, Flemming, Kelly, Awad, Issam A.
Publicado 2021

Case Report: Management of Traumatic Carotid-Cavernous Fistulas in the Acute Setting of Penetrating Brain Injury

por Loggini, Andrea, Kass-Hout, Tareq, Awad, Issam A., El Ammar, Faten, Kramer, Christopher L., Goldenberg, Fernando D., Lazaridis, Christos, Mansour, Ali
Publicado 2022

CSF and serum inflammatory response and association with outcomes in spontaneous intracerebral hemorrhage with intraventricular extension: an analysis of the CLEAR-III Trial

por Gusdon, Aaron M., Thompson, Carol B., Quirk, Kendel, Mayasi, Yunis M., Avadhani, Radhika, Awad, Issam A., Hanley, Daniel F., Ziai, Wendy C.
Publicado 2021

Inflammatory Mechanisms in a Neurovascular Disease: Cerebral Cavernous Malformation

por Li, Ying, Srinath, Abhinav, Alcazar-Felix, Roberto J., Hage, Stephanie, Bindal, Akash, Lightle, Rhonda, Shenkar, Robert, Shi, Changbin, Girard, Romuald, Awad, Issam A.
Publicado 2023

Intracranial Pressure and Cerebral Perfusion Pressure in Large Spontaneous Intracranial Hemorrhage and Impact of Minimally Invasive Surgery

por Al-Kawaz, Mais N., Li, Yunke, Thompson, Richard E., Avadhani, Radhika, de Havenon, Adam, Gruber, Joshua, Awad, Issam, Hanley, Daniel F., Ziai, Wendy
Publicado 2021

Association Between Intraventricular Alteplase Use and Parenchymal Hematoma Volume in Patients With Spontaneous Intracerebral Hemorrhage and Intraventricular Hemorrhage

por Witsch, Jens, Roh, David J., Avadhani, Radhika, Merkler, Alexander E., Kamel, Hooman, Awad, Issam, Hanley, Daniel F., Ziai, Wendy C., Murthy, Santosh B.
Publicado 2021

Developmental venous anomalies are a genetic primer for cerebral cavernous malformations

por Snellings, Daniel A., Girard, Romuald, Lightle, Rhonda, Srinath, Abhinav, Romanos, Sharbel, Li, Ying, Chen, Chang, Ren, Aileen A., Kahn, Mark L., Awad, Issam A., Marchuk, Douglas A.
Publicado 2022

Propranolol as therapy for cerebral cavernous malformations: a cautionary note

por Shenkar, Robert, Moore, Thomas, Benavides, Christian, Lightle, Rhonda, Detter, Matthew R., Hobson, Nicholas, Girard, Romuald, DeBiasse, Dorothy, Patrucco, Mary, Gallione, Carol, Zabramski, Joseph M., Marchuk, Douglas A., Awad, Issam A.
Publicado 2022

Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations

por Lopez-Ramirez, Miguel Alejandro, Fonseca, Gregory, Zeineddine, Hussein A., Girard, Romuald, Moore, Thomas, Pham, Angela, Cao, Ying, Shenkar, Robert, de Kreuk, Bart-Jan, Lagarrigue, Frederic, Lawler, Jack, Glass, Christopher K., Awad, Issam A., Ginsberg, Mark H.
Publicado 2017

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis

por Chapman, Eric M., Lant, Benjamin, Ohashi, Yota, Yu, Bin, Schertzberg, Michael, Go, Christopher, Dogra, Deepika, Koskimäki, Janne, Girard, Romuald, Li, Yan, Fraser, Andrew G., Awad, Issam A., Abdelilah-Seyfried, Salim, Gingras, Anne-Claude, Derry, W. Brent
Publicado 2019

Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scie...

por Akers, Amy, Al-Shahi Salman, Rustam, A. Awad, Issam, Dahlem, Kristen, Flemming, Kelly, Hart, Blaine, Kim, Helen, Jusue-Torres, Ignacio, Kondziolka, Douglas, Lee, Cornelia, Morrison, Leslie, Rigamonti, Daniele, Rebeiz, Tania, Tournier-Lasserve, Elisabeth, Waggoner, Darrel, Whitehead, Kevin
Publicado 2017

Quantitative Susceptibility Mapping and Vessel Wall Imaging as Screening Tools to Detect Microbleed in Sentinel Headache

por Ishii, Daizo, Nakagawa, Daichi, Zanaty, Mario, Roa, Jorge A., Al Kasab, Sami, Shaban, Amir, Hudson, Joseph S., Osorno-Cruz, Carlos, Byer, Stefano, Allan, Lauren, Torner, James C., Awad, Issam A., Carroll, Timothy J., Samaniego, Edgar A., Hasan, David M.
Publicado 2020

Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signaling

por Zhou, Zinan, Tang, Alan T., Wong, Weng-Yew, Bamezai, Sharika, Goddard, Lauren M., Shenkar, Robert, Zhou, Su, Yang, Jisheng, Wright, Alexander C., Foley, Matthew, Arthur, J. Simon C., Whitehead, Kevin J., Awad, Issam A., Li, Dean Y., Zheng, Xiangjian, Kahn, Mark L.
Publicado 2016

Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu

por Goods, Brittany A., Askenase, Michael H., Markarian, Erica, Beatty, Hannah E., Drake, Riley S., Fleming, Ira, DeLong, Jonathan H., Philip, Naomi H., Matouk, Charles C., Awad, Issam A., Zuccarello, Mario, Hanley, Daniel F., Love, J. Christopher, Shalek, Alex K., Sansing, Lauren H.
Publicado 2021

EXCEPTIONAL AGGRESSIVENESS OF CEREBRAL CAVERNOUS MALFORMATION DISEASE ASSOCIATED WITH PDCD10 MUTATIONS

por Shenkar, Robert, Shi, Changbin, Rebeiz, Tania, Stockton, Rebecca A., McDonald, David A., Mikati, Abdul Ghani, Zhang, Lingjiao, Austin, Cecilia, Akers, Amy L., Gallione, Carol J., Rorrer, Autumn, Gunel, Murat, Min, Wang, De Souza, Jorge Marcondes, Lee, Connie, Marchuk, Douglas A., Awad, Issam A.
Publicado 2014

Phenotypic Characterization of Murine Models of Cerebral Cavernous Malformations

por Zeineddine, Hussein A., Girard, Romuald, Saadat, Laleh, Shen, Le, Lightle, Rhonda, Moore, Thomas, Cao, Ying, Hobson, Nick, Shenkar, Robert, Avner, Kenneth, Chaudager, Kiranj, Koskimäki, Janne, Polster, Sean P., Fam, Maged D., Shi, Changbin, Lopez-Ramirez, Miguel Alejandro, Tang, Alan T., Gallione, Carol, Kahn, Mark L., Ginsberg, Mark, Marchuk, Douglas A., Awad, Issam A.
Publicado 2018