SNP Selection in Genome-Wide and Candidate Gene Studies via Penalized Logistic Regression

por Ayers, Kristin L, Cordell, Heather J
Publicado 2010

Identification of Grouped Rare and Common Variants via Penalized Logistic Regression

por Ayers, Kristin L, Cordell, Heather J
Publicado 2013

Analysis of Genetic Analysis Workshop 18 data with gene-based penalized regression

por Ayers, Kristin L, Cordell, Heather J
Publicado 2014

Penalized-regression-based multimarker genotype analysis of Genetic Analysis Workshop 17 data

por Ayers, Kristin L, Mamasoula, Chrysovalanto, Cordell, Heather J
Publicado 2011

Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles

por Conley, Jason M., Sun, Hongmao, Ayers, Kristin L., Zhu, Hu, Chen, Rong, Shen, Min, Hall, Matthew D., Ren, Hongxia
Publicado 2021

A loss of function variant in CASP7 protects against Alzheimer’s disease in homozygous APOE ε4 allele carriers

por Ayers, Kristin L., Mirshahi, Uyenlinh L., Wardeh, Amr H., Murray, Michael F., Hao, Ke, Glicksberg, Benjamin S., Li, Shuyu, Carey, David J., Chen, Rong
Publicado 2016

Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis

por Darlay, Rebecca, Ayers, Kristin L., Mells, George F., Hall, Lynsey S., Liu, Jimmy Z., Almarri, Mohamed A., Alexander, Graeme J., Jones, David E., Sandford, Richard N., Anderson, Carl A., Cordell, Heather J.
Publicado 2018

A composite biomarker of neutrophil-lymphocyte ratio and hemoglobin level correlates with clinical response to PD-1 and PD-L1 inhibitors in advanced non-small cell lung cancers

por Ayers, Kristin L., Ma, Meng, Debussche, Gaspard, Corrigan, David, McCafferty, Jonathan, Lee, Kyeryoung, Newman, Scott, Zhou, Xiang, Hirsch, Fred R., Mack, Philip C., Liu, Jane J., Schadt, Eric E., Chen, Rong, Li, Shuyu D.
Publicado 2021

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks

por Glicksberg, Benjamin S., Li, Li, Badgeley, Marcus A., Shameer, Khader, Kosoy, Roman, Beckmann, Noam D., Pho, Nam, Hakenberg, Jörg, Ma, Meng, Ayers, Kristin L., Hoffman, Gabriel E., Dan Li, Shuyu, Schadt, Eric E., Patel, Chirag J., Chen, Rong, Dudley, Joel T.
Publicado 2016

Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma

por Mack, Philip C, Klein, Michael I, Ayers, Kristin L, Zhou, Xiang, Guin, Sunny, Fink, Marc, Rossi, Michael, AI-Kateb, Hussam, O’Connell, Timmy, Hantash, Feras M, Oh, William K, Newman, Scott, Schadt, Eric E, Chen, Rong, Hirsch, Fred R
Publicado 2022

Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment

por Ayers, Kristin L, Glicksberg, Benjamin S, Garfield, Alastair S, Longerich, Simonne, White, Joseph A, Yang, Pengwei, Du, Lei, Chittenden, Thomas W, Gulcher, Jeffery R, Roy, Sophie, Fiedorek, Fred, Gottesdiener, Keith, Cohen, Sarah, North, Kari E, Schadt, Eric E, Li, Shuyu D, Chen, Rong, Van der Ploeg, Lex H T
Publicado 2018

Analysis of Real‐World Data to Investigate the Impact of Race and Ethnicity on Response to Programmed Cell Death‐1 and Programmed Cell Death‐Ligand 1 Inhibitors in Advanced Non‐Sma...

por Ayers, Kristin L., Mullaney, Tommy, Zhou, Xiang, Liu, Jane J., Lee, Kyeryoung, Ma, Meng, Jones, Scott, Li, Li, Redfern, Arielle, Jappe, Whitney, Liu, Zongzhi, Goldsweig, Howard, Yadav, Kamlesh K., Hahner, Nicholas, Dietz, Matthew, Zimmerman, Michelle, Prentice, Tony, Newman, Scott, Veluswamy, Rajwanth, Wisnivesky, Juan, Hirsch, Fred R., Oh, William K., Li, Shuyu D., Schadt, Eric E., Chen, Rong
Publicado 2021

Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

por Glicksberg, Benjamin S., Amadori, Letizia, Akers, Nicholas K., Sukhavasi, Katyayani, Franzén, Oscar, Li, Li, Belbin, Gillian M., Ayers, Kristin L., Shameer, Khader, Badgeley, Marcus A., Johnson, Kipp W., Readhead, Ben, Darrow, Bruce J., Kenny, Eimear E., Betsholtz, Christer, Ermel, Raili, Skogsberg, Josefin, Ruusalepp, Arno, Schadt, Eric E., Dudley, Joel T., Ren, Hongxia, Kovacic, Jason C., Giannarelli, Chiara, Li, Shuyu D., Björkegren, Johan L. M., Chen, Rong
Publicado 2019

Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot

por Cordell, Heather J., Töpf, Ana, Mamasoula, Chrysovalanto, Postma, Alex V., Bentham, Jamie, Zelenika, Diana, Heath, Simon, Blue, Gillian, Cosgrove, Catherine, Granados Riveron, Javier, Darlay, Rebecca, Soemedi, Rachel, Wilson, Ian J., Ayers, Kristin L., Rahman, Thahira J., Hall, Darroch, Mulder, Barbara J.M., Zwinderman, Aelko H., van Engelen, Klaartje, Brook, J. David, Setchfield, Kerry, Bu'Lock, Frances A., Thornborough, Chris, O'Sullivan, John, Stuart, A. Graham, Parsons, Jonathan, Bhattacharya, Shoumo, Winlaw, David, Mital, Seema, Gewillig, Marc, Breckpot, Jeroen, Devriendt, Koen, Moorman, Antoon F.M., Rauch, Anita, Lathrop, G. Mark, Keavney, Bernard D., Goodship, Judith A.
Publicado 2013

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

por Deelen, Joris, Beekman, Marian, Uh, Hae-Won, Broer, Linda, Ayers, Kristin L., Tan, Qihua, Kamatani, Yoichiro, Bennet, Anna M., Tamm, Riin, Trompet, Stella, Guðbjartsson, Daníel F., Flachsbart, Friederike, Rose, Giuseppina, Viktorin, Alexander, Fischer, Krista, Nygaard, Marianne, Cordell, Heather J., Crocco, Paolina, van den Akker, Erik B., Böhringer, Stefan, Helmer, Quinta, Nelson, Christopher P., Saunders, Gary I., Alver, Maris, Andersen-Ranberg, Karen, Breen, Marie E., van der Breggen, Ruud, Caliebe, Amke, Capri, Miriam, Cevenini, Elisa, Collerton, Joanna C., Dato, Serena, Davies, Karen, Ford, Ian, Gampe, Jutta, Garagnani, Paolo, de Geus, Eco J.C., Harrow, Jennifer, van Heemst, Diana, Heijmans, Bastiaan T., Heinsen, Femke-Anouska, Hottenga, Jouke-Jan, Hofman, Albert, Jeune, Bernard, Jonsson, Palmi V., Lathrop, Mark, Lechner, Doris, Martin-Ruiz, Carmen, Mcnerlan, Susan E., Mihailov, Evelin, Montesanto, Alberto, Mooijaart, Simon P., Murphy, Anne, Nohr, Ellen A., Paternoster, Lavinia, Postmus, Iris, Rivadeneira, Fernando, Ross, Owen A., Salvioli, Stefano, Sattar, Naveed, Schreiber, Stefan, Stefánsson, Hreinn, Stott, David J., Tiemeier, Henning, Uitterlinden, André G., Westendorp, Rudi G.J., Willemsen, Gonneke, Samani, Nilesh J., Galan, Pilar, Sørensen, Thorkild I.A., Boomsma, Dorret I., Jukema, J. Wouter, Rea, Irene Maeve, Passarino, Giuseppe, de Craen, Anton J.M., Christensen, Kaare, Nebel, Almut, Stefánsson, Kári, Metspalu, Andres, Magnusson, Patrik, Blanché, Hélène, Christiansen, Lene, Kirkwood, Thomas B.L., van Duijn, Cornelia M., Franceschi, Claudio, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline
Publicado 2014

A meta-analysis of genome-wide association studies identifies multiple longevity genes

por Deelen, Joris, Evans, Daniel S., Arking, Dan E., Tesi, Niccolò, Nygaard, Marianne, Liu, Xiaomin, Wojczynski, Mary K., Biggs, Mary L., van der Spek, Ashley, Atzmon, Gil, Ware, Erin B., Sarnowski, Chloé, Smith, Albert V., Seppälä, Ilkka, Cordell, Heather J., Dose, Janina, Amin, Najaf, Arnold, Alice M., Ayers, Kristin L., Barzilai, Nir, Becker, Elizabeth J., Beekman, Marian, Blanché, Hélène, Christensen, Kaare, Christiansen, Lene, Collerton, Joanna C., Cubaynes, Sarah, Cummings, Steven R., Davies, Karen, Debrabant, Birgit, Deleuze, Jean-François, Duncan, Rachel, Faul, Jessica D., Franceschi, Claudio, Galan, Pilar, Gudnason, Vilmundur, Harris, Tamara B., Huisman, Martijn, Hurme, Mikko A., Jagger, Carol, Jansen, Iris, Jylhä, Marja, Kähönen, Mika, Karasik, David, Kardia, Sharon L. R., Kingston, Andrew, Kirkwood, Thomas B. L., Launer, Lenore J., Lehtimäki, Terho, Lieb, Wolfgang, Lyytikäinen, Leo-Pekka, Martin-Ruiz, Carmen, Min, Junxia, Nebel, Almut, Newman, Anne B., Nie, Chao, Nohr, Ellen A., Orwoll, Eric S., Perls, Thomas T., Province, Michael A., Psaty, Bruce M., Raitakari, Olli T., Reinders, Marcel J. T., Robine, Jean-Marie, Rotter, Jerome I., Sebastiani, Paola, Smith, Jennifer, Sørensen, Thorkild I. A., Taylor, Kent D., Uitterlinden, André G., van der Flier, Wiesje, van der Lee, Sven J., van Duijn, Cornelia M., van Heemst, Diana, Vaupel, James W., Weir, David, Ye, Kenny, Zeng, Yi, Zheng, Wanlin, Holstege, Henne, Kiel, Douglas P., Lunetta, Kathryn L., Slagboom, P. Eline, Murabito, Joanne M.
Publicado 2019

Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes

por Deelen, Joris, Evans, Daniel S., Arking, Dan E., Tesi, Niccolò, Nygaard, Marianne, Liu, Xiaomin, Wojczynski, Mary K., Biggs, Mary L., van der Spek, Ashley, Atzmon, Gil, Ware, Erin B., Sarnowski, Chloé, Smith, Albert V., Seppälä, Ilkka, Cordell, Heather J., Dose, Janina, Amin, Najaf, Arnold, Alice M., Ayers, Kristin L., Barzilai, Nir, Becker, Elizabeth J., Beekman, Marian, Blanché, Hélène, Christensen, Kaare, Christiansen, Lene, Collerton, Joanna C., Cubaynes, Sarah, Cummings, Steven R., Davies, Karen, Debrabant, Birgit, Deleuze, Jean-François, Duncan, Rachel, Faul, Jessica D., Franceschi, Claudio, Galan, Pilar, Gudnason, Vilmundur, Harris, Tamara B., Huisman, Martijn, Hurme, Mikko A., Jagger, Carol, Jansen, Iris, Jylhä, Marja, Kähönen, Mika, Karasik, David, Kardia, Sharon L. R., Kingston, Andrew, Kirkwood, Thomas B. L., Launer, Lenore J., Lehtimäki, Terho, Lieb, Wolfgang, Lyytikäinen, Leo-Pekka, Martin-Ruiz, Carmen, Min, Junxia, Nebel, Almut, Newman, Anne B., Nie, Chao, Nohr, Ellen A., Orwoll, Eric S., Perls, Thomas T., Province, Michael A., Psaty, Bruce M., Raitakari, Olli T., Reinders, Marcel J. T., Robine, Jean-Marie, Rotter, Jerome I., Sebastiani, Paola, Smith, Jennifer, Sørensen, Thorkild I. A., Taylor, Kent D., Uitterlinden, André G., van der Flier, Wiesje, van der Lee, Sven J., van Duijn, Cornelia M., van Heemst, Diana, Vaupel, James W., Weir, David, Ye, Kenny, Zeng, Yi, Zheng, Wanlin, Holstege, Henne, Kiel, Douglas P., Lunetta, Kathryn L., Slagboom, P. Eline, Murabito, Joanne M.
Publicado 2021